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Current Applications of Liposome Formulations

Double-Membraned Liposomes Sculpted by Poliovirus 3AB Protein. Wang, J., J.B. Ptacek, K. Kirkegaard, and E. Bullitt. (2013). J Biol Chem [PubMed]

Label-free characterization of Peptide-lipid interactions using immobilized lipodisks. Agmo Hernandez, V., K. Reijmar, and K. Edwards. (2013). Anal Chem 85:7377-84. [PubMed]

In-Situ Transmission Electron Microscopy of Liposomes in an Aqueous Environment. Hoppe, S.M., D.Y. Sasaki, A.N. Kinghorn, and K. Hattar. (2013). Langmuir [PubMed]

Controlled Fusion of Synthetic Lipid Membrane Vesicles. Ma, M. and D. Bong. (2013). Acc Chem Res [PubMed]

In situ modification of plain liposomes with lipidated coiled coil forming peptides induces efficient membrane fusion. Versluis, F., J. Voskuhl, B. van Kolck, H.R. Zope, M. Bremmer, T. Albregtse, and A. Kros. (2013). J Am Chem Soc [PubMed]

Detection of Nanosized Ordered Domains in DOPC/DPPC and DOPC/Ch Binary Lipid Mixture Systems of Large Unilamellar Vesicles Using a TEMPO Quenching Method. Suga, K. and H. Umakoshi. (2013). Langmuir [PubMed]

Cholesterol and sphingomyelin drive ligand-independent T-cell antigen receptor nanoclustering. Molnar, E., M. Swamy, M. Holzer, K. Beck-Garcia, R. Worch, C. Thiele, G. Guigas, K. Boye, I.F. Luescher, P. Schwille, R. Schubert, and W.W. Schamel. (2012). J Biol Chem 287:42664-74. [PubMed]

Role for Phospholipid Flippase Complex of ATP8A1 and CDC50A Proteins in Cell Migration. Kato, U., H. Inadome, M. Yamamoto, K. Emoto, T. Kobayashi, and M. Umeda. (2013). J Biol Chem 288:4922-34. [PubMed]

Lipid nanobilayers to host biological nanopores for DNA translocations. Gopfrich, K., C.V. Kulkarni, O.J. Pambos, and U.F. Keyser. (2013). Langmuir 29:355-64. [PubMed]

Phospholipid flippases lem3p-dnf1p and lem3p-dnf2p are involved in the sorting of the tryptophan permease tat2p in yeast. Hachiro, T., T. Yamamoto, K. Nakano, and K. Tanaka. (2013). J Biol Chem 288:3594-608. [PubMed]

Effects of sphingomyelin headgroup size on interactions with ceramide. Artetxe, I., C. Sergelius, M. Kurita, S. Yamaguchi, S. Katsumura, J.P. Slotte, and T. Maula. (2013). Biophys J 104:604-12. [PubMed]

Nanomechanics of Lipid Encapsulated Microbubbles with Functional Coatings. Abou-Saleh, R.H., S.A. Peyman, K. Critchley, S.D. Evans, and N.H. Thomson. (2013). Langmuir [PubMed]

Nonlinear Scaling of Surface Water Diffusion with Bulk Water Viscosity of Crowded Solutions. Franck, J.M., J.A. Scott, and S. Han. (2013). J Am Chem Soc [PubMed]

Noble Gases in Pure Lipid Membranes. Sierra-Valdez, F.J. and J.C. Ruiz-Suarez. (2013). J Phys Chem B [PubMed]

Dynamic Lipid Lateral Segregation Driven by Lauryl Cyclodextrin Interactions at the Membrane Surface. Roux, M., E. Sternin, V. Bonnet, C. Fajolles, and F. Djedaini-Pilard. (2013). Langmuir [PubMed]

Effect of Headgroup on the Physicochemical Properties of Phospholipid Bilayers in Electric Fields: Size Matters. Madrid, E. and S.L. Horswell. (2013). Langmuir [PubMed]

A Photodependent Switch of Liposome Stability and Permeability. Randles, E.G. and P.R. Bergethon. (2013). Langmuir [PubMed]

Controlling and Monitoring Orientation of DNA Nanoconstructs on Lipid Surfaces. Lundberg, E.P., B. Feng, A. Saeid Mohammadi, L.M. Wilhelmsson, and B. Norden. (2012). Langmuir [PubMed]

Lipid Reassembly in Asymmetric Langmuir-Blodgett/Langmuir-Schaeffer Bilayers. Yuan, J., C. Hao, M. Chen, P. Berini, and S. Zou. (2012). Langmuir December 7, 2012. Abstract

Curvature Forces in Membrane Lipid-Protein Interactions. Brown, M.F. (2012). Biochemistry. Abstract

Lysophosphatidic acid targets vascular and oncogenic pathways via RAGE signaling. Rai, V., F. Toure, S. Chitayat, R. Pei, F. Song, Q. Li, J. Zhang, R. Rosario, R. Ramasamy, W.J. Chazin, and A.M. Schmidt. (2012). J Exp Med. Abstract

Acyl-Chain Mismatch Driven Superlattice Arrangements in DPPC/DLPC/Cholesterol Bilayers. Brian Cannon, Anthony Lewis, Pentti Somerharju, Jorma Virtanen, Juyang Huang and Kwan Hon Cheng. J. Phys. Chem. B, 2010, 114 (31), pp 10105–10113. Abstract

Critical Role of Membrane Cholesterol in Exocytosis Revealed by Single Platelet Study. Shencheng Ge, James G. White, and Christy L. Haynes. ACS Chem. Biol., 2010, 5 (9), pp 819–828. Abstract

Effect of Cholesterol Nanodomains on the Targeting of Lipid-Based Gene Delivery in Cultured Cells. Long Xu and Thomas J. Anchordoquy. Mol. Pharmaceutics, 2010, 7 (4), pp 1311–1317. Abstract

Effects of PEO−PPO−PEO Triblock Copolymers on Phospholipid Membrane Integrity under Osmotic Stress. Jia-Yu Wang, Jaemin Chin, Jeremy D. Marks and Ka Yee C. Lee. Langmuir, 2010, 26 (15), pp 12953–12961. Abstract

Equilibria of Phosphatidylcholine − Ca2+ Ions in Monolayer at the Air/Water Interface. Aneta D. Petelska, Anna Niemcunowicz-Janica, Michał Szeremeta and Zbigniew A. Figaszewski. Langmuir, 2010, 26 (16), pp 13359–13363. Abstract

Evaluation of the Specific Interactions between Glycodendrimeric Porphyrins, Free or Incorporated into Liposomes, and Concanavaline A by Fluorescence Spectroscopy, Surface Pressure, and QCM-D Measurements. A. Makky, J. P. Michel, A. Kasselouri , E. Briand, Ph. Maillard  and V. Rosilio. Langmuir, 2010, 26 (15), pp 12761–12768. Abstract

Formation of Fluid Lamellar Phase and Large Unilamellar Vesicles with Octadecyl Methyl Sulfoxide/Cholesterol Mixtures. Zhong-Kai Cui, Guillaume Bastiat and Michel Lafleur. Langmuir, 2010, 26 (15), pp 12733–12739. Abstract

Formation of Silica Precipitates on Membrane Surfaces in Two and Three Dimensions. Anja Bernecker, Joanna Ziomkowska, Svenja Heitmuller, Ralph Wieneke, Armin Geyer and Claudia Steinem. Langmuir, 2010, 26 (16), pp 13422–13428. Abstract

Interfacial Water Structure Associated with Phospholipid Membranes Studied by Phase-Sensitive Vibrational Sum Frequency Generation Spectroscopy. Xiangke Chen, Wei Hua, Zishuai Huang and Heather C. Allen. J. Am. Chem. Soc., 2010, 132 (32), pp 11336–11342. Abstract

Molecular Simulation of the DMPC-Cholesterol Phase Diagram. Frederick J.-M. de Meyer, Ayelet Benjamini, Jocelyn M. Rodgers, Yannick Misteli and Berend Smit. J. Phys. Chem. B, 2010, 114 (32), pp 10451–10461. Abstract

pH-Triggered Release from Nonphospholipid LUVs Modulated by the pKa of the Included Fatty Acid. Thida Phoeung, Pauline Aubron, Gaulthier Rydzek and Michel Lafleur. Langmuir, 2010, 26 (15), pp 12769–12776. Abstract

Protein and Small Molecule Recognition Properties of Deep Cavitands in a Supported Lipid Membrane Determined by Calcination-Enhanced SPR Spectroscopy. Ying Liu, Puhong Liao, Quan Cheng and Richard J. Hooley. J. Am. Chem. Soc., 2010, 132 (30), pp 10383-10390. Abstract

Structure and Orientation of Water at Charged Lipid Monolayer/Water Interfaces Probed by Heterodyne-Detected Vibrational Sum Frequency Generation Spectroscopy. Jahur A. Mondal, Satoshi Nihonyanagi, Shoichi Yamaguchi and Tahei Tahara. J. Am. Chem. Soc., 2010, 132 (31), pp 10656–10657. Abstract

Tailoring Lipoplex Composition to the Lipid Composition of Plasma Membrane: A Trojan Horse for Cell Entry? Cristina Marchini, Daniela Pozzi, Maura Montani, Cinzia Alfonsi, Augusto Amici, Heinz Amenitsch, Sofia Candeloro De Sanctis and Giulio Caracciolo. Langmuir, 2010, 26 (17), pp 13867–13873. Abstract

A Novel Octreotide Modified Lipid Vesicle Improved the Anticancer Efficacy of Doxorubicin in Somatostatin Receptor 2 Positive Tumor Models. Junlin Zhang, Wu Jin, Xueqing Wang, Jiancheng Wang, Xuan Zhang and Qiang Zhang. Mol. Pharmaceutics, 2010, 7 (4), pp 1159–1168. Abstract

Colchicine-Loaded Lipid Bilayer-Coated 50 nm Mesoporous Nanoparticles Efficiently Induce Microtubule Depolymerization upon Cell Uptake. Valentina Cauda, Hanna Engelke, Anna Sauer, Delphine Arcizet, Christoph Brauchle, Joachim Radler and Thomas Bein Nano Lett., 2010, 10 (7), pp 2484–2492. Abstract

Cytoplasmic Delivery of Liposomes into MCF-7 Breast Cancer Cells Mediated by Cell-Specific Phage Fusion Coat Protein. Tao Wang, Shenghong Yang, Valery A. Petrenko and Vladimir P. Torchilin. Mol. Pharmaceutics, 2010, 7 (4), pp 1149–1158. Abstract

Effect of Cholesterol and Sugar on the Penetration of Glycodendrimeric Phenylporphyrins into Biomimetic Models of Retinoblastoma Cells Membranes. A. Makky, J. P. Michel, S. Ballut, A. Kasselouri, Ph. Maillard and V. Rosilio. Langmuir, 2010, 26 (13), pp 11145–11156. Abstract

Effect of pH and Ibuprofen on the Phospholipid Bilayer Bending Modulus. Mohan Babu Boggara, Antonio Faraone and Ramanan Krishnamoorti. J. Phys. Chem. B, 2010, 114 (24), pp 8061–8066. Abstract

Environmental Effects Dominate the Folding of Oligocholates in Solution, Surfactant Micelles, and Lipid Membranes. Hongkwan Cho and Yan Zhao. J. Am. Chem. Soc., 2010, 132 (28), pp 9890–9899. Abstract

Lipid Composition Affects the Rate of Photosensitized Dissipation of Cross-Membrane Diffusion Potential on Liposomes. Shany Ytzhak, Joseph P. Wuskell, Leslie M. Loew and Benjamin Ehrenberg. J. Phys. Chem. B, 2010, 114 (31), pp 10097–10104. Abstract

Liposomal Cu-64 Labeling Method Using Bifunctional Chelators: Poly(ethylene glycol) Spacer and Chelator Effects. Jai Woong Seo, Lisa M. Mahakian, Azadeh Kheirolomoom, Hua Zhang, Claude F. Meares, Riccardo Ferdani, Carolyn J. Anderson and Katherine W. Ferrara. Bioconjugate Chem., 2010, 21 (7), pp 1206–1215. Abstract

Membrane Perturbation Activity of Cationic Phenylene Ethynylene Oligomers and Polymers: Selectivity against Model Bacterial and Mammalian Membranes. Ying Wang, Yanli Tang, Zhijun Zhou, Eunkyung Ji, Gabriel P. Lopez, Eva Y. Chi, Kirk S. Schanze and David G. Whitten. Langmuir, 2010, 26 (15), pp 12509–12514. Abstract

Normal Mode Gating Motions of a Ligand-Gated Ion Channel Persist in a Fully Hydrated Lipid Bilayer Model. Edward J. Bertaccini, James R. Trudell and Erik Lindahl. ACS Chem. Neurosci., 2010, 1 (8), pp 552–558. Abstract

Occupancy of Nonannular Lipid Binding Sites on KcsA Greatly Increases the Stability of the Tetrameric Protein. I. Triano, F. N. Barrera, M. L. Renart, M. L. Molina, G. Fern ndez-Ballester, J. A. Poveda, A. M. Fern ndez, J. A. Encinar, A. V. Ferrer-Montiel, D. Otzen and J. M. Gonz lez-Ros. Biochemistry, 2010, 49 (25), pp 5397–5404. Abstract

Controlled Release from Bilayer-Decorated Magnetoliposomes via Electromagnetic Heating. Yanjing Chen, Arijit Bose and Geoffrey D. Bothun. ACS Nano, 2010, 4 (6), pp 3215–3221. Abstract

Electrically Addressable, Biologically Relevant Surface-Supported Bilayers. Janice Lin, John Szymanski, Peter C. Searson and Kalina Hristova. Langmuir, 2010, 26 (14), pp 12054–12059. Abstract

Influence of Hydrophobic Structures on the Plasma Membrane Permeability of Lipidlike Molecules. Kenichi Niikura, Katsuyuki Nambara, Takaharu Okajima, Yasutaka Matsuo and Kuniharu Ijiro. Langmuir, 2010, 26 (12), pp 9170–9175. Abstract

Label-Free Imaging of Lipophilic Bioactive Molecules during Lipid Digestion by Multiplex Coherent Anti-Stokes Raman Scattering Microspectroscopy. James P. R. Day, Gianluca Rago, Katrin F. Domke, Krassimir P. Velikov and Mischa Bonn. J. Am. Chem. Soc., 2010, 132 (24), pp 8433–8439. Abstract

Lipid Concentration Effects on the Amyloidogenic apoC-II60−70 Peptide: A Computational Study. Nevena Todorova, Andrew Hung and Irene Yarovsky. J. Phys. Chem. B, 2010, 114 (23), pp 7974–7982. Abstract

Material Transfer in Cubosome−Emulsion Mixtures: Effect of Alkane Chain Length. Anniina Salonen, Christian Moitzi, Stefan Salentinig and Otto Glatter. Langmuir, 2010, 26 (13), pp 10670–10676. Abstract

Matrix-Enhanced Secondary Ion Mass Spectrometry (ME SIMS) Using Room Temperature Ionic Liquid Matrices. Jennifer J. D. Fitzgerald, Paul Kunnath and Amy V. Walker. Anal. Chem., 2010, 82 (11), pp 4413–4419. Abstract

Membrane Proteins Diffuse as Dynamic Complexes with Lipids. Perttu S. Niemel, Markus S. Miettinen, Luca Monticelli, Henrik Hammaren, Par Bjelkmar, Teemu Murtola, Erik Lindahl  and Ilpo Vattulainen. J. Am. Chem. Soc., 2010, 132 (22), pp 7574–7575. Abstract

Membrane-Mediated Effect on Ion Channels Induced by the Anesthetic Drug Ketamine. Hansjorg Jerabek, Georg Pabst, Michael Rappolt and Thomas Stockner. J. Am. Chem. Soc., 2010, 132 (23), pp 7990–7997. Abstract

Model Lipid Bilayer with Facile Diffusion of Lipids and Integral Membrane Proteins. Tingting Wang, Colin Ingram and James C. Weisshaar. Langmuir, 2010, 26 (13), pp 11157–11164. Abstract

Molecular Recognition at the Membrane−Water Interface: Controlling Integral Peptide Helices by Off-Membrane Nucleobase Pairing. Philipp Erik Schneggenburger, Stefan Mullar, Brigitte Worbs, Claudia Steinem and Ulf Diederichsen. J. Am. Chem. Soc., 2010, 132 (23), pp 8020–8028. Abstract

Molecular Restructuring of Water and Lipids upon the Interaction of DNA with Lipid Monolayers. R. Kramer Campen, Thuy T. M. Ngo, Maria Sovago, Jean-Marie Ruysschaert and Mischa Bonn. J. Am. Chem. Soc., 2010, 132 (23), pp 8037–8047. Abstract

Phosphatidylglucoside Forms Specific Lipid Domains on the Outer Leaflet of the Plasma Membrane. Motohide Murate, Tomohiro Hayakawa, Kumiko Ishii, Hironori Inadome, Peter Greimel, Masaki Watanabe, Yasuko Nagatsuka, Kazuki Ito, Yukishige Ito, Hiroshi Takahashi, Yoshio Hirabayashi and Toshihide Kobayashi. Biochemistry, 2010, 49 (23), pp 4732–4739. Abstract

Photocatalytic Hydrogen Evolution from Rhenium(I) Complexes to [FeFe] Hydrogenase Mimics in Aqueous SDS Micellar Systems: A Biomimetic Pathway. Hong-Yan Wang, Wen-Guang Wang, Gang Si, Feng Wang, Chen-Ho Tung and Li-Zhu Wu. Langmuir, 2010, 26 (12), pp 9766–9771. Abstract

Role of Glycolipids in Lipid Rafts: A View through Atomistic Molecular Dynamics Simulations with Galactosylceramide. Anette Hall, Tomasz Rog, Mikko Karttunen, Ilpo Vattulainen. J. Phys. Chem. B, 2010, 114 (23), pp 7797–7807. Abstract

Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types. Jeffery B. Klauda, Richard M. Venable, J. Alfredo Freites, Joseph W. O’Connor, Douglas J. Tobias, Carlos Mondragon-Ramirez, Igor Vorobyov, Alexander D. MacKerell, Jr. and Richard W. Pastor. J. Phys. Chem. B, 2010, 114 (23), pp 7830–7843. Abstract

Zirconium Ion Mediated Formation of Liposome Multilayers. Sebastian C. Burgel, Orane Guillaume-Gentil, Limin Zheng, Janos Voros and Marta Bally. Langmuir, 2010, 26 (13), pp 10995–11002. Abstract

Supported Lipid Bilayers on Mica and Silicon Oxide: Comparison of the Main Phase Transition Behavior. Heiko M. Seeger, Alessandro Di Cerbo, Andrea Alessandrini and Paolo Facci. J. Phys. Chem. B, 2010, 114 (27), pp 8926–8933. Abstract

Effect of Rhamnolipids on Pulmonary Surfactant Foam Films. R. Cohen, R. Todorov, G. Vladimirov and D. Exerowa. Langmuir, 2010, 26 (12), pp 9423–9428. Abstract

Exchange Kinetics of Protein-Functionalized Micelles and Liposomes Studied by Förster Resonance Energy Transfer. Sanne W. A. Reulen and Maarten Merkx. Bioconjugate Chem., 2010, 21 (5), pp 860–866. Abstract

Myelin Basic Protein and Myelin Protein 2 Act Synergistically to Cause Stacking of Lipid Bilayers. Swetha Suresh, Chaozhan Wang, Rahul Nanekar, Petri Kursula and J. Michael Edwardson. Biochemistry, 2010, 49 (16), pp 3456–3463. Abstract

Microfluidic Directed Self-Assembly of Liposome-Hydrogel Hybrid Nanoparticles. Jennifer S. Hong, Samuel M. Stavis, Silvia H. DePaoli Lacerda, Laurie E. Locascio, Srinivasa R. Raghavan and Michael Gaitan. Langmuir, 2010, 26 (13), pp 11581–11588. Abstract

Liposomal Formulation of Retinoids Designed for Enzyme Triggered Release. Palle J. Pedersen, Sidsel K. Adolph, Arun K. Subramanian, Ahmad Arouri, Thomas L. Andresen, Ole G. Mouritsen, Robert Madsen, Mogens W. Madsen, Gunther H. Peters and Mads H. Clausen. J. Med. Chem., 2010, 53 (9), pp 3782–3792. Abstract

Liposomes Remain Intact When Complexed with Polycationic Brushes. Alexander A. Yaroslavov, Andrei V. Sybachin, Marc Schrinner, Matthias Ballauff, Larisa Tsarkova, Ellina Kesselman, Judith Schmidt, Yeshayahu Talmon and Fredric M. Menger. J. Am. Chem. Soc., 2010, 132 (17), pp 5948–5949. Abstract

Membrane Lipids Influence Protein Complex Assembly-Disassembly. Leah Shin, Won Jin Cho, Jeremy D. Cook, Timothy L. Stemmler and Bhanu P. Jena. J. Am. Chem. Soc., 2010, 132 (16), pp 5596–5597. Abstract

PEGylated Phospholipid Membrane on Polymer Cushion and Its Interaction with Cholesterol. Yibang Zhang, Yanyan Chen and Gang Jin. Langmuir, 2010, 26 (13), pp 11140–11144. Abstract

Phase Segregation of Untethered Zwitterionic Model Lipid Bilayers Observed on Mercaptoundecanoic-Acid-Modified Gold by AFM Imaging and Force Mapping. Shell Ip, James K. Li and Gilbert C. Walker. Langmuir, 2010, 26 (13), pp 11060–11070. Abstract

pH-Dependent Distribution of Chlorin e6 Derivatives across Phospholipid Bilayers Probed by NMR Spectroscopy. Martina Vermathen, Mattia Marzorat, Peter Vermathen and Peter Bigler. Langmuir, 2010, 26 (13), pp 11085–11094. Abstract

Photodynamic Activity of Liposomal Photosensitizers via Energy Transfer from Antenna Molecules to [60]Fullerene. Atsushi Ikeda, Motofusa Akiyama, Takuya Ogawa and Tatsuo Takeya. ACS Med. Chem. Lett., 2010, 1 (3), pp 115–119. Abstract

Probing the “Charge Cluster Mechanism” in Amphipathic Helical Cationic Antimicrobial Peptides. Raquel F. Epand, W. Lee Maloy, Ayyalusamy Ramamoorthy and Richard M. Epand. Biochemistry, 2010, 49 (19), pp 4076–4084. Abstract

Rheological Properties of a Two Phase Lipid Monolayer at the Air/Water Interface: Effect of the Composition of the Mixture. N. Wilke, F. Vega Mercado and B. Maggio. Langmuir, 2010, 26 (13), pp 11050–11059. Abstract

Solvent-Exposed Tails as Prestalk Transition States for Membrane Fusion at Low Hydration. Yuliya G. Smirnova, Siewert-Jan Marrink, Reinhard Lipowsky and Volker Knecht. J. Am. Chem. Soc., 2010, 132 (19), pp 6710–6718. Abstract