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My Lipid Did Not Dissolve, What Can I Do?

Stock solutions of lipids in a biologically compatible solvent may precipitate when diluted with aqueous media. Precipitates often redissolve with sonication and/or warming. We recommend ensuring the precipitate has completely redissolved before using the solution (if possible). However, another option would be to deliver the lipid in suspension rather than as a true solution (sonicate the suspension immediately before dispensing to ensure a uniform suspension), or to deliver the lipid as a micelle or SUV.