999995 | Edelfosine

1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine


Powder

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5mg 999995P-5mg 999995P-5mg 1 x 5mg $88.00

Chloroform

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5mg 999995C-5mg 999995C-5mg 1 x 5mg 5mg/mL 1mL $88.00
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Edelfosine

Edelfosine

1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C27H58NO6P
Percent Composition
C 61.92%, H 11.16%, N 2.67%, O 18.33%, P 5.91%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
77286-66-9
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
523.726
Exact Mass
523.400
Synonyms
<p>ET-18-OCH32-O-methyl PAF C-18PC(18:0e/1:0e)</p>

Ausili A, Martinez Valera P, Torrecillas A, Gómez-Murcia V, deGodos AM, Corbalan-Garcia S, Teruel JA, Gomez-Fernandez JC. The anticancer agent edelfosine exhibits a high affinity for cholesterol and disorganizes liquid ordered membrane structures. Langmuir. 2018 Jun 20. doi: 10.1021/acs.langmuir.8b01539. [Epub ahead of print]

PubMed ID: 29924618

Castro, B.M., A. Fedorov, V. Hornillos, J. Delgado, A.U. Acuna, F. Mollinedo, and M. Prieto. (2013). Edelfosine and Miltefosine Effects on Lipid Raft Properties: Membrane Biophysics in Cell Death by Antitumor Lipids. J Phys Chem B Jul 3;117(26):7929-40. doi: 10.1021/jp401407d. Epub 2013 Jun 24.

PubMed ID: 23738749