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5-PAHSA | 900410

5-(palmitoyloxy)octadecanoic acid

900410C

Chloroform

1 mg
$68.00
5 mg
$270.00
10 mg
$480.00

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PAHSA levels correlate highly with insulin sensitivity and are reduced in adipose tissue and serum of insulin-resistant humans. In adipocytes, PAHSAs signal through GPR120 to enhance insulin-stimulated glucose uptake. Thus, FAHFAs are endogenous lipids with the potential to treat type 2 diabetes.
 
Avanti has obtained a license from the patent holder to manufacture these products for research use.
Molecular Formula
C34H66O4
Percent Composition
C 75.78%, H 12.34%, O 11.88%
Purity
>99%
Stability
1 Years
Storage
-20°C
CAS Number
1481636-41-2
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
538.885
Exact Mass
538.496
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Notes
GIF Graphics File. 
GIF Graphics File. 
MDL Molfile. 
CDX File. 
Kolar, M.J., S.S. Kamat, W.H. Parsons, E.A. Homan, T. Maher, O.D. Peroni, I. Syed, K. Fjeld, A. Molven, B.B. Kahn, B.F. Cravatt, and A. Saghatelian. (2016). Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase. Biochemistry 55:4636-41. [PubMed]

Yore, M.M., I. Syed, P.M. Moraes-Vieira, T. Zhang, M.A. Herman, E.A. Homan, R.T. Patel, J. Lee, S. Chen, O.D. Peroni, A.S. Dhaneshwar, A. Hammarstedt, U. Smith, T.E. McGraw, A. Saghatelian, and B.B. Kahn. (2014). Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects. Cell 159:318-32. [PubMed]