900409 | 9-PAHSA

9-(palmitoyloxy)octadecanoic acid


Chloroform

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1mg 900409C-1mg 900409C-1mg 1 x 1mg 1mg/mL 1mL $74.55
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9-PAHSA

9-PAHSA

9-(palmitoyloxy)octadecanoic acid

PAHSA levels correlate highly with insulin sensitivity and are reduced in adipose tissue and serum of insulin-resistant humans. In adipocytes, PAHSAs signal through GPR120 to enhance insulin-stimulated glucose uptake. Thus, FAHFAs are endogenous lipids with the potential to treat type 2 diabetes.
Avanti has obtained a license from the patent holder to manufacture these products for research use.
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C34H66O4
Percent Composition
C 75.78%, H 12.34%, O 11.88%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
1481636-31-0
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
538.885
Exact Mass
538.496

Pham TH, Vidal NP, Manful CF, Fillier TA, Pumphrey RP, Doody KM, Thomas RH. Moose and Caribou as Novel Sources of Functional Lipids: Fatty Acid Esters of Hydroxy Fatty Acids, Diglycerides and Monoacetyldiglycerides. Molecules. 2019 Jan 10;24(2). pii: E232. doi: 10.3390/molecules24020232.

PubMed ID: 30634564

Kolar MJ, Kamat SS, Parsons WH, Homan EA, Maher T, Peroni OD, Syed I, Fjeld K, Molven A, Kahn BB, Cravatt BF, Saghatelian A. Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase. Biochemistry. 2016 Aug 23;55(33):4636-41. doi: 10.1021/acs.biochem.6b00565. Epub 2016 Aug 10.

PubMed ID: 27509211

Yore MM, Syed I, Moraes-Vieira PM, Zhang T, Herman MA, Homan EA, Patel RT, Lee J, Chen S, Peroni OD, Dhaneshwar AS, Hammarstedt A, Smith U, McGraw TE, Saghatelian A, Kahn BB. Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects. Cell. 2014 Oct 9;159(2):318-32. doi: 10.1016/j.cell.2014.09.035.

PubMed ID: 25303528