890899 | DODMA

1,2-dioleyloxy-3-dimethylaminopropane


Chloroform

Size SKU Packaging Price
100mg 890899C-100mg 890899C-100mg 1 x 100mg 25mg/mL 4mL $175.00
500mg 890899C-500mg 890899C-500mg 5 x 100mg 25mg/mL 4mL $600.00
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DODMA

DODMA

1,2-dioleyloxy-3-dimethylaminopropane

Cationic lipids such as DODMA are considered non-viral carriers for gene therapy. DODMA is used for the preparation of cationic liposomes or lipid nanoparticles (LNP) needing a neutral or low zeta potential. DODMA is extremely effective at encapsulating nucleic acids due to its ability to temporarily reduce pH.

Zhou Chen, Aili Zhang, Zhaogang Yang, Xinmei Wang, Lingqian Chang, Zhaofeng Chen and Ly James Lee, “Application of DODMA and Derivatives in Cationic Nanocarriers for Gene Delivery”, Current Organic Chemistry (2016) 20: 1813. https://doi.org/10.2174/138527...

Hygroscopic
No
Light Sensitive
No
Molecular Formula

C41H81NO2

Percent Composition

C 79.41% H 13.17% N 2.26% O 5.16%

Purity
>99%
Stability
1 Year
Storage Temperature
-20
CAS Number
104162-47-2
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
620.100
Exact Mass
619.630

Patel S, Ryals RC, Weller KK, Pennesi ME, Sahay G. Lipid nanoparticles for delivery of messenger RNA to the back of the eye. J Control Release. 2019 Apr 12;303:91-100. doi: 10.1016/j.jconrel.2019.04.015. [Epub ahead of print]

PubMed ID: 30986436