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14:1 EPC (Tf Salt) | 890717

1,2-dimyristoleoyl-sn-glycero-3-ethylphosphocholine (Tf salt)

890717O

Oil

200 mg
$635.00
100 mg
$370.00
10 mg
$107.00
25 mg
$135.00

890717C

Chloroform

10 mg
$92.00
25 mg
$120.00
100 mg
$355.00
200 mg
$620.00

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O-alkyl phosphatidylcholines constitute the first chemically stable triesters of biological lipid structures and the first cationic derivatives of phospholipids consisting entirely of biological metabolites linked with ester bonds. The lipid has low toxicity and is biodegradable.
Molecular Formula
C39H73F3NO11PS
Percent Composition
C 54.98%, H 8.64%, F 6.69%, N 1.64%, O 20.66%, P 3.64%, S 3.76%
Purity
>99%
Stability
6 Months
Storage
-20°C
CAS Number
1246304-44-8
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
852.031
Exact Mass
851.459
Synonyms
1,2-di-(9Z-tetradecenoyl)-sn-glycero-3-ethylphosphocholine (Tf salt)
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Notes
GIF Graphics File. 
GIF Graphics File. 
MDL Molfile. 
CDX File. 
Koynova, R., Tenchov, B., Wang, L., MacDonald, R.C. (2009) Hydrophobic moiety of cationic lipids strongly modulates their transfection activity. Mol Pharm. 6:951-8. [PubMed]

Tenchov, B.G., Wang, L., Koynova, R., MacDonald, R.C. (2008) Modulation of a membrane lipid lamellar-nonlamellar phase transition by cationic lipids: a measure for transfection efficiency. Biochim Biophys Acta. 1778:2405-12. [PubMed]



Koynova, R., Tarahovsky, Y.S., Wang, L., MacDonald, R.C. (2007) Lipoplex formulation of superior efficacy exhibits high surface activity and fusogenicity, and readily releases DNA. Biochim Biophys Acta. 1768:375-86. [PubMed]



Koynova, R., Wang, L., MacDonald, R.C. (2007) Synergy in lipofection by cationic lipid mixtures: superior activity at the gel-liquid crystalline phase transition. J Phys Chem B. 111:7786-95. [PubMed]

Wang, L., MacDonald, R.C. (2007) Synergistic effect between components of mixtures of cationic amphipaths in transfection of primary endothelial cells. Mol Pharm. 4:615-23. [PubMed]