890705 | 16:0-18:1 EPC (Cl Salt)

1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine (chloride salt)


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Size SKU Packaging Price
10mg 890705P-10mg 890705P-10mg 1 x 10mg $112.00
25mg 890705P-25mg 890705P-25mg 1 x 25mg $142.00

Chloroform

Size SKU Packaging Price
10mg 890705C-10mg 890705C-10mg 1 x 10mg 10mg/mL 1mL $112.00
25mg 890705C-25mg 890705C-25mg 1 x 25mg 10mg/mL 2.5mL $142.00
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16:0-18:1 EPC (Cl Salt)

16:0-18:1 EPC (Cl Salt)

1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine (chloride salt)

O-alkyl phosphatidylcholines constitute the first chemically stable triesters of biological lipid structures and the first cationic derivatives of phospholipids consisting entirely of biological metabolites linked with ester bonds. The lipid has low toxicity and is biodegradable.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C44H87NO8PCl
Percent Composition
C 64.09%, H 10.63%, Cl 4.30%, N 1.70%, O 15.52%, P 3.76%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
328250-19-7
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
824.590
Exact Mass
823.586
Synonyms

1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-ethylphosphocholine (chloride salt)

Zong W, Thingholm B, Itel F, Schattling PS, Brodszkij E, Mayer D, Stenger S, Goldie KN, Han X, Städler B. Phospholipid-Block Copolymer Hybrid Vesicles with Lysosomal Escape Ability. Langmuir. 2018 Jun 1. doi: 10.1021/acs.langmuir.8b01073. [Epub ahead of print]

PubMed ID: 29776311

Koynova, R., Tenchov, B., Wang, L., MacDonald, R.C. (2009) Hydrophobic moiety of cationic lipids strongly modulates their transfection activity. Mol Pharm. 6:951-8.

PubMed ID: 19341312

Tenchov, B.G., Wang, L., Koynova, R., MacDonald, R.C. (2008) Modulation of a membrane lipid lamellar-nonlamellar phase transition by cationic lipids: a measure for transfection efficiency. Biochim Biophys Acta. 1778:2405-12.

PubMed ID: 18722340

Koynova, R., Tarahovsky, Y.S., Wang, L., MacDonald, R.C. (2007) Lipoplex formulation of superior efficacy exhibits high surface activity and fusogenicity, and readily releases DNA. Biochim Biophys Acta. 1768:375-86.

PubMed ID: 17156744

Koynova, R., Wang, L., MacDonald, R.C. (2007) Synergy in lipofection by cationic lipid mixtures: superior activity at the gel-liquid crystalline phase transition. J Phys Chem B. 111:7786-95.

PubMed ID: 18722340

Wang, L., MacDonald, R.C. (2007) Synergistic effect between components of mixtures of cationic amphipaths in transfection of primary endothelial cells. Mol Pharm. 4:615-23.

PubMed ID: 17408283