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18:1 EPC (Cl Salt) | 890704

1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (chloride salt)

890704C

Chloroform

10 mg
$92.00
25 mg
$120.00
100 mg
$355.00
200 mg
$620.00

890704P

Powder

10 mg
$107.00
25 mg
$135.00
100 mg
$370.00
200 mg
$635.00

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O-alkyl phosphatidylcholines constitute the first chemically stable triesters of biological lipid structures and the first cationic derivatives of phospholipids consisting entirely of biological metabolites linked with ester bonds. The lipid has low toxicity and is biodegradable.
Molecular Formula
C46H89NO8PCl
Percent Composition
C 64.95%, H 10.55%, Cl 4.17%, N 1.65%, O 15.05%, P 3.64%
Purity
>99%
Stability
6 Months
Storage
-20°C
CAS Number
474945-24-9
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
850.628
Exact Mass
849.601
Synonyms
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-ethylphosphocholine (chloride salt)
EDOPC
DOPC+
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Notes
GIF Graphics File. 
GIF Graphics File. 
MDL Molfile. 
CDX File. 
Koynova, R., Tenchov, B., Wang, L., MacDonald, R.C. (2009) Hydrophobic moiety of cationic lipids strongly modulates their transfection activity. Mol Pharm. 6:951-8. [PubMed]

Tenchov, B.G., Wang, L., Koynova, R., MacDonald, R.C. (2008) Modulation of a membrane lipid lamellar-nonlamellar phase transition by cationic lipids: a measure for transfection efficiency. Biochim Biophys Acta. 1778:2405-12. [PubMed]



Koynova, R., Tarahovsky, Y.S., Wang, L., MacDonald, R.C. (2007) Lipoplex formulation of superior efficacy exhibits high surface activity and fusogenicity, and readily releases DNA. Biochim Biophys Acta. 1768:375-86. [PubMed]



Koynova, R., Wang, L., MacDonald, R.C. (2007) Synergy in lipofection by cationic lipid mixtures: superior activity at the gel-liquid crystalline phase transition. J Phys Chem B. 111:7786-95. [PubMed]

Wang, L., MacDonald, R.C. (2007) Synergistic effect between components of mixtures of cationic amphipaths in transfection of primary endothelial cells. Mol Pharm. 4:615-23. [PubMed]