890703 | 18:0 EPC (Cl Salt)
1,2-distearoyl-sn-glycero-3-ethylphosphocholine (chloride salt)
18:0 EPC (Cl Salt)
1,2-distearoyl-sn-glycero-3-ethylphosphocholine (chloride salt)
O-alkyl phosphatidylcholines constitute the first chemically stable triesters of biological lipid structures and the first cationic derivatives of phospholipids consisting entirely of biological metabolites linked with ester bonds. The lipid has low toxicity and is biodegradable.
CAS Registry Number is a Registered Trademark of the American Chemical Society
Patel S, Ryals RC, Weller KK, Pennesi ME, Sahay G. Lipid nanoparticles for delivery of messenger RNA to the back of the eye. J Control Release. 2019 Apr 12;303:91-100. doi: 10.1016/j.jconrel.2019.04.015. [Epub ahead of print]
PubMed ID: 30986436Koynova, R., Tenchov, B., Wang, L., MacDonald, R.C. (2009) Hydrophobic moiety of cationic lipids strongly modulates their transfection activity. Mol Pharm. 6:951-8.
PubMed ID: 19341312Tenchov, B.G., Wang, L., Koynova, R., MacDonald, R.C. (2008) Modulation of a membrane lipid lamellar-nonlamellar phase transition by cationic lipids: a measure for transfection efficiency. Biochim Biophys Acta. 1778:2405-12.
PubMed ID: 18722340Koynova, R., Tarahovsky, Y.S., Wang, L., MacDonald, R.C. (2007) Lipoplex formulation of superior efficacy exhibits high surface activity and fusogenicity, and readily releases DNA. Biochim Biophys Acta. 1768:375-86.
PubMed ID: 17156744Wang, L., MacDonald, R.C. (2007) Synergistic effect between components of mixtures of cationic amphipaths in transfection of primary endothelial cells. Mol Pharm. 4:615-23.
PubMed ID: 17408283Gillissen JJJ, Tabaei SR, Jackman JA, Cho NJ Effect of Glucose on the Mobility of Membrane-Adhering Liposomes Langmuir. 2017 Dec 19. doi: 10.1021/acs.langmuir.7b03364.
PubMed ID: 29200303- Certificate of Analysis (Lot No. 890703C-25MG-A-017 and 6347CJA017)
- Certificate of Analysis (Lot No. 890703P-25MG-A-017 and 6347PJA017)
- Certificate of Analysis (Lot No. 890703P-25MG-B-017 and 6347PJB017)
- Certificate of Analysis (Lot No. 890703C-25MG-B-017 and 6347CJB017)
- Certificate of Analysis (Lot No. 890703P-25MG-C-017 and 6347PJC017)
- Certificate of Analysis (Lot No. 890703C-25MG-C-017 and 6347CJC017)
- Certificate of Analysis (Lot No. 890703P-25MG-D-017 and 6347PJD017)
- Certificate of Analysis (Lot No. 890703P-25MG-E-017 and 6347PJE017)
- Certificate of Analysis (Lot No. 890703P-25MG-A-018 and 6347PJA018)
- Certificate of Analysis (Lot No. 890703P-25MG-B-018 and 6347PJB018)
- Certificate of Analysis (Lot No. 890703P-25MG-D-018 and 6347PJD018)
- Certificate of Analysis (Lot No. 890703P-25MG-A-019 and 6347PJA019)
- Certificate of Analysis (Lot No. 890703C-25MG-B-018 and 6347CJB018)