12:0 EPC (Cl Salt) | 890700
1,2-dilauroyl-sn-glycero-3-ethylphosphocholine (chloride salt)
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- O-alkyl phosphatidylcholines constitute the first chemically stable triesters of biological lipid structures and the first cationic derivatives of phospholipids consisting entirely of biological metabolites linked with ester bonds. The lipid has low toxicity and is biodegradable.
- Molecular Formula
- Percent Composition
- C 59.50%, H 10.13%, Cl 5.17%, N 2.04%, O 18.65%, P 4.51%
- 1 Years
- CAS Number
CAS Registry Number is a Registered Trademark of the American Chemical Society
- Molecular Weight
- Exact Mass
- 1,2-didodecanoyl-sn-glycero-3-ethylphosphocholine (chloride salt)
Tenchov, B.G., Wang, L., Koynova, R., MacDonald, R.C. (2008) Modulation of a membrane lipid lamellar-nonlamellar phase transition by cationic lipids: a measure for transfection efficiency. Biochim Biophys Acta. 1778:2405-12. [PubMed]
Koynova, R., Tarahovsky, Y.S., Wang, L., MacDonald, R.C. (2007) Lipoplex formulation of superior efficacy exhibits high surface activity and fusogenicity, and readily releases DNA. Biochim Biophys Acta. 1768:375-86. [PubMed]
Koynova, R., Wang, L., MacDonald, R.C. (2007) Synergy in lipofection by cationic lipid mixtures: superior activity at the gel-liquid crystalline phase transition. J Phys Chem B. 111:7786-95. [PubMed]
Wang, L., MacDonald, R.C. (2007) Synergistic effect between components of mixtures of cationic amphipaths in transfection of primary endothelial cells. Mol Pharm. 4:615-23. [PubMed]