890700 | 12:0 EPC (Cl Salt)

1,2-dilauroyl-sn-glycero-3-ethylphosphocholine (chloride salt)


Chloroform

Size SKU Packaging Price
10mg 890700C-10mg 890700C-10mg 1 x 10mg 10mg/mL 1mL $112.00

Powder

Size SKU Packaging Price
10mg 890700P-10mg 890700P-10mg 1 x 10mg $112.00
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12:0 EPC (Cl Salt)

12:0 EPC (Cl Salt)

1,2-dilauroyl-sn-glycero-3-ethylphosphocholine (chloride salt)

O-alkyl phosphatidylcholines constitute the first chemically stable triesters of biological lipid structures and the first cationic derivatives of phospholipids consisting entirely of biological metabolites linked with ester bonds. The lipid has low toxicity and is biodegradable.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C34H69NO8PCl
Percent Composition
C 59.50%, H 10.13%, Cl 5.17%, N 2.04%, O 18.65%, P 4.51%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
474945-22-7
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
686.340
Exact Mass
685.445
Synonyms
<p>1,2-didodecanoyl-sn-glycero-3-ethylphosphocholine (chloride salt)</p>
Koynova, R., Tenchov, B., Wang, L., MacDonald, R.C. (2009) Hydrophobic moiety of cationic lipids strongly modulates their transfection activity. Mol Pharm. 6:951-8. [PubMed] Tenchov, B.G., Wang, L., Koynova, R., MacDonald, R.C. (2008) Modulation of a membrane lipid lamellar-nonlamellar phase transition by cationic lipids: a measure for transfection efficiency. Biochim Biophys Acta. 1778:2405-12. [PubMed] Koynova, R., Tarahovsky, Y.S., Wang, L., MacDonald, R.C. (2007) Lipoplex formulation of superior efficacy exhibits high surface activity and fusogenicity, and readily releases DNA. Biochim Biophys Acta. 1768:375-86. [PubMed] Koynova, R., Wang, L., MacDonald, R.C. (2007) Synergy in lipofection by cationic lipid mixtures: superior activity at the gel-liquid crystalline phase transition. J Phys Chem B. 111:7786-95. [PubMed] Wang, L., MacDonald, R.C. (2007) Synergistic effect between components of mixtures of cationic amphipaths in transfection of primary endothelial cells. Mol Pharm. 4:615-23. [PubMed]