880230 | 18:1 PEG5000 PE

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] (ammonium salt)

Powder

Size SKU Packaging Price
25mg 880230P-25mg 880230P-25mg 1 x 25mg $153.75
200mg 880230P-200mg 880230P-200mg 2 x 100mg $328.00

Chloroform

Size SKU Packaging Price
25mg 880230C-25mg 880230C-25mg 1 x 25mg 10mg/mL 2.5mL $153.75
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18:1 PEG5000 PE

18:1 PEG5000 PE

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] (ammonium salt)

Representative Structure

The molecular weight and exact mass are averages based on the polydispersity of PEG.

Hygroscopic
Yes
Light Sensitive
No
Molecular Formula

C269H535N2O123P (average FW due to polydispersity of PEG)

Percent Composition

C 55.73%, H 9.30%, N 0.48%, O 33.95% P 0.53%

Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
474922-90-2
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
5797.100
Exact Mass
5793.540
Synonyms
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[carbonyl-methoxy(polyethylene glycol)-5000] (ammonium salt)

Xu X, Hou B, Fulzele A, Masubuchi T, Zhao Y, Wu Z, Hu Y, Jiang Y, Ma Y, Wang H, Bennett EJ, Fu G, Hui E. PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2. J Cell Biol. 2020 Jun 1;219(6):e201905085. doi: 10.1083/jcb.201905085. PMID: 32437509; PMCID: PMC7265324.

 PubMed ID: 32437509

Pan J, Attia SA, Subhan MA, Filipczak N, Mendes LP, Li X, Kishan Yalamarty SS, Torchilin VP. Monoclonal Antibody 2C5-Modified Mixed Dendrimer Micelles for Tumor-Targeted Codelivery of Chemotherapeutics and siRNA. Mol Pharm. 2020 May 4;17(5):1638-1647. doi: 10.1021/acs.molpharmaceut.0c00075. Epub 2020 Apr 10. PMID: 32233497.

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Das S, Lazenby RA, Yuan Z, White RJ, Park YC. Effect of Laser Irradiation on Reversibility and Drug Release of Light-Activatable Drug-Encapsulated Liposomes. Langmuir. 2020 Apr 7;36(13):3573-3582. doi: 10.1021/acs.langmuir.0c00215. Epub 2020 Mar 27. PMID: 32188250.

 PubMed ID: 32188250

Sasmal DK, Feng W, Roy S, Leung P, He Y, Cai C, Cao G, Lian H, Qin J, Hui E, Schreiber H, Adams EJ, Huang J. TCR-pMHC bond conformation controls TCR ligand discrimination. Cell Mol Immunol. 2019 Sep 17. doi: 10.1038/s41423-019-0273-6. [Epub ahead of print]

 PubMed ID: 31530899

Ditlev JA, Vega AR, Köster DV, Su X, Tani T, Lakoduk AM, Vale RD, Mayor S, Jaqaman K, Rosen MK. A composition-dependent molecular clutch between T cell signaling condensates and actin. Elife. 2019 Jul 3;8. pii: e42695. doi: 10.7554/eLife.42695.

 PubMed ID: 31268421

Pan J, Mendes LP, Yao M, Filipczak N, Garai S, Thakur GA, Sarisozen C, Torchilin VP. Polyamidoamine dendrimers-based nanomedicine for combination therapy with siRNA and chemotherapeutics to overcome multidrug resistance. Eur J Pharm Biopharm. 2019 Mar;136:18-28. doi: 10.1016/j.ejpb.2019.01.006. Epub 2019 Jan 8.

 PubMed ID: 30633973

Pan J, Mendes LP, Yao M, Filipczak N, Garai S, Thakur GA, Sarisozen C, Torchilin VP. Polyamidoamine dendrimers-based nanomedicine for combination therapy with siRNA and chemotherapeutics to overcome multidrug resistance. Eur J Pharm Biopharm. 2019 Mar;136:18-28. doi: 10.1016/j.ejpb.2019.01.006. Epub 2019 Jan 8.

 PubMed ID: 30633973