DSPE-PEG(2000)-DBCO | 880229

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[dibenzocyclooctyl(polyethylene glycol)-2000] (ammonium salt)



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Cu-free click chemistry with readily synthesized biarylazacyclooctynones. The reaction of azides with strained alkynes, such as cyclooctynes, readily forms a triazole product without the need for a toxic catalyst.
Refer also to DSPE-PEG Azide Avanti Number 880228
1 Year
Molecular Weight
3077.798 (average MW due to polydispersity of PEG)
GIF Graphics File. 
GIF Graphics File. 
MDL Molfile. 
CDX File. 
Jewett, J.C., E.M. Sletten, and C.R. Bertozzi. (2010). Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynones. J Am Chem Soc 132:3688-90. [PubMed] Artificial Membrane Fusion Triggered by Strain-Promoted Alkyne–Azide Cycloaddition, Stuart A. Whitehead†, Christopher D. McNitt‡, Samuel I. Mattern-Schain†, Adam J. Carr†, Shahrina Alam†, Vladimir V. Popik‡, and Michael D. Best*†  Bioconjugate Chem., Article ASAP, DOI: 10.1021/acs.bioconjchem.6b00578 [PubMed]