880180 | C16 PEG2000 Ceramide
N-palmitoyl-sphingosine-1-{succinyl[methoxy(polyethylene glycol)2000]}
C16 PEG2000 Ceramide
N-palmitoyl-sphingosine-1-{succinyl[methoxy(polyethylene glycol)2000]}
Representative Structure
The molecular weight and exact mass are averages based on the polydispersity of PEG.
C129H253NO51 (average MW due to polydispersity of PEG)
C 58.81%, H 9.68%, N 0.53%, O 30.97%
CAS Registry Number is a Registered Trademark of the American Chemical Society
Fattore L, Campani V, Ruggiero CF, Salvati V, Liguoro D, Scotti L, Botti G, Ascierto PA, Mancini R, De Rosa G, Ciliberto G. In Vitro Biophysical and Biological Characterization of Lipid Nanoparticles Co-Encapsulating Oncosuppressors miR-199b-5p and miR-204-5p as Potentiators of Target Therapy in Metastatic Melanoma. Int J Mol Sci. 2020 Mar 12;21(6):1930. doi: 10.3390/ijms21061930. PMID: 32178301; PMCID: PMC7139872.
PubMed ID: 32178301Thanki K, van Eetvelde D, Geyer A, Fraire J, Hendrix R, Van Eygen H, Putteman E, Sami H, de Souza Carvalho-Wodarz C, Franzyk H, Nielsen HM, Braeckmans K, Lehr CM, Ogris M, Foged C. Mechanistic profiling of the release kinetics of siRNA from lipidoid-polymer hybrid nanoparticles in vitro and in vivo after pulmonary administration. J Control Release. 2019 Sep 28;310:82-93. doi: 10.1016/j.jconrel.2019.08.004. Epub 2019 Aug 6.
PubMed ID: 31398360Thanki K, Papai S, Lokras A, Rose F, Falkenberg E, Franzyk H, Foged C. Application of a Quality-By-Design Approach to Optimise Lipid-Polymer Hybrid Nanoparticles Loaded with a Splice-Correction Antisense Oligonucleotide: Maximising Loading and Intracellular Delivery. Pharm Res. 2019 Jan 9;36(3):37. doi: 10.1007/s11095-018-2566-3.
PubMed ID: 30623253Maroof H, Islam F, Dong L, Ajjikuttira P, Gopalan V, McMillan NAJ, Lam AK. Liposomal Delivery of miR-34b-5p Induced Cancer Cell Death in Thyroid Carcinoma Cells. 2018 Dec 11;7(12). pii: E265. doi: 10.3390/cells7120265.
PubMed ID: 30544959- Certificate of Analysis (Lot No. 880180P-1G-A-025 and 6300PQA025)
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- Certificate of Analysis (Lot No. 880180P-200MG-A-026 and 6300PNA026)
- Certificate of Analysis (Lot No. 880180P-25MG-A-026 and 6300PJA026)
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- Certificate of Analysis (Lot No. 880180P-25MG-B-025 and 6300PJB025)
- Certificate of Analysis (Lot No. 880180P-200MG-B-025 and 6300PNB025)
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