880134 | PMA

Polymethacrylate Copolymer (N−C4−52−6.9)


Powder

Size SKU Packaging Price
100mg 880134P-100mg 880134P-100mg 1 x 100mg $263.00
500mg 880134P-500mg 880134P-500mg 1 x 500mg $920.00
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PMA

PMA

Polymethacrylate Copolymer (N−C4−52−6.9)

Perform Structure and Functional Studies on a Variety of Membrane Proteins

Advantages of PMA Based Lipid Nanodiscs:

Spontaneously Forms Lipid Nanodiscs through Fragmentation of the Lipid Bilayer

Amenable to Biophysical Characterization using CD, UV/vis, and Fluorescence Spectroscopy

Ability to Product Nanodiscs of Various Sizes

Larger PMA Polymer Nanodiscs can be aligned in a magnetic field allowing for solid-state NMR studies on membrane proteins or peptides

Hygroscopic
No
Light Sensitive
No
Molecular Formula

C21H40NO6S+

Percent Composition

Fraction of Butyl Methacrylate (BMA) in Copolymer: ~0.52

Fraction of Methyl Acryoloxy Choline (MAC) in Copolymer: ~0.48

Degree of Polymerization (DP): ~39.00

Purity
>99%
Storage Temperature
-20°C
CAS Number
2315261-99-3
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
0.000
Exact Mass
0.000

Yasuhara K, Arakida J, Ravula T, Ramadugu SK, Sahoo B, Kikuchi JI, Ramamoorthy A. Spontaneous Lipid Nanodisc Fomation by Amphiphilic Polymethacrylate Copolymers. J Am Chem Soc. 2017 Dec 27;139(51):18657-18663. doi: 10.1021/jacs.7b10591. Epub 2017 Dec 5.

PubMed ID: 29171274