880134 | PMA

Polymethacrylate Copolymer (N−C4−52−6.9)


Powder

Size SKU Packaging Price
100mg 880134P-100mg 880134P-100mg 1 x 100mg $250.00
500mg 880134P-500mg 880134P-500mg 1 x 500mg $875.00
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PMA

PMA

Polymethacrylate Copolymer (N−C4−52−6.9)

Perform Structure and Functional Studies on a Variety of Membrane Proteins

Advantages of PMA Based Lipid Nanodiscs:

Spontaneously Forms Lipid Nanodiscs through Fragmentation of the Lipid Bilayer

Amenable to Biophysical Characterization using CD, UV/vis, and Fluorescence Spectroscopy

Ability to Product Nanodiscs of Various Sizes

Larger PMA Polymer Nanodiscs can be aligned in a magnetic field allowing for solid-state NMR studies on membrane proteins or peptides

Hygroscopic
No
Light Sensitive
No
Molecular Formula

C21H40NO6S+

Percent Composition

Fraction of Butyl Methacrylate (BMA) in Copolymer: ~0.52

Fraction of Methyl Acryoloxy Choline (MAC) in Copolymer: ~0.48

Degree of Polymerization (DP): ~39.00

Purity
>99%
Storage Temperature
-20°C
Molecular Weight
0.000
Exact Mass
0.000

Yasuhara K, Arakida J, Ravula T, Ramadugu SK, Sahoo B, Kikuchi JI, Ramamoorthy A. Spontaneous Lipid Nanodisc Fomation by Amphiphilic Polymethacrylate Copolymers. J Am Chem Soc. 2017 Dec 27;139(51):18657-18663. doi: 10.1021/jacs.7b10591. Epub 2017 Dec 5.

PubMed ID: 29171274