DSPE-PEG(2000) Folate | 880124
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-2000] (ammonium salt)
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- Molecular Formula
- Percent Composition
- C 56.13%, H 8.92%, N 4.77%, O 29.22%, P 0.96%
- According to the published synthetic protocol, the product will be 80-85% gamma conjugated and contain 15-20% of the other positional isomer. This does not seem to impact the functionality.
- 1 Years
- CAS Number
CAS Registry Number is a Registered Trademark of the American Chemical Society
- Molecular Weight
- Exact Mass
- Dissolved in chloroform/methanol (9:1, v/v)
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Shiokawa, T., Y. Hattori, K. Kawano, Y. Ohguchi, H. Kawakami, K. Toma, and Y. Maitani. (2005). Effect of polyethylene glycol linker chain length of folate-linked microemulsions loading aclacinomycin A on targeting ability and antitumor effect in vitro and in vivo. Clin Cancer Res 11:2018-25. [PubMed]
Zhang, Y., L. Guo, R.W. Roeske, A.C. Antony, and H.N. Jayaram. (2004). Pteroyl-gamma-glutamate-cysteine synthesis and its application in folate receptor-mediated cancer cell targeting using folate-tethered liposomes. Anal Biochem 332:168-77. [PubMed]
Gabizon, A., A.T. Horowitz, D. Goren, D. Tzemach, F. Mandelbaum-Shavit, M.M. Qazen, and S. Zalipsky. (1999). Targeting folate receptor with folate linked to extremities of poly(ethylene glycol)-grafted liposomes: in vitro studies. Bioconjug Chem 10:289-98. [PubMed]