880122 | DSPE-PEG(2000) Cyanur

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[cyanur(polyethylene glycol)-2000] (ammonium salt)


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DSPE-PEG(2000) Cyanur

DSPE-PEG(2000) Cyanur

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[cyanur(polyethylene glycol)-2000] (ammonium salt)

Cyanur PEG-PE is an endgroup functionalized PEG-lipid conjugate used for attachment of peptides, antibodies, etc., under mild basic conditions. Proteins can be coupled to this membrane anchor without the need for previous derivatization.

Representative Structure

The formula weight and exact mass are averages based on the polydispersity of PEG. 

Hygroscopic
Yes
Light Sensitive
No
Molecular Formula

C135H265Cl2N6O54P  (average MW due to polydispersity of PEG)

Percent Composition

C 55.18%, H 9.09%, Cl 2.41%, N 2.86%, O 29.40%, P 1.05%

Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
1246304-74-4
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
2938.467
Exact Mass
2935.729
Synonyms
<p>Cyanur-PEG<sub>2000</sub>-DSPE</p>

Kheradmandi M, Ackers I, Burdick MM, Malgor R, Farnoud AM. Targeting Dysfunctional Vascular Endothelial Cells Using Immunoliposomes Under Flow Conditions. Cell Mol Bioeng. 2020 May 4;13(3):189-199. doi: 10.1007/s12195-020-00616-1. PMID: 32426057; PMCID: PMC7225235.

PubMed ID: 32426057

Bakowsky H, Richter T, Kneuer C, Hoekstra D, Rothe U, Bendas G, Ehrhardt C, Bakowsky U. Adhesion characteristics and stability assessment of lectin-modified liposomes for site-specific drug delivery. Biochim Biophys Acta. 2008 Jan;1778(1):242-9. doi: 10.1016/j.bbamem.2007.09.033. Epub 2007 Oct 10. PMID: 17964278.

PubMed ID: 17964278

Bendas G, Krause A, Bakowsky U, Vogel J, Rothe U. Targetability of novel immunoliposomes prepared by a new antibody conjugation technique. Int J Pharm. 1999 Apr 20;181(1):79-93. doi: 10.1016/s0378-5173(99)00002-2. PMID: 10370205.

PubMed ID: 10370205