880120 | 18:0 PEG2000 PE

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt)

18:0 PEG2000 PE

Chloroform

Size SKU Packaging Price
25mg 880120C-25mg 880120C-25mg 1 x 25mg 10mg/mL 2.5mL $176.50
200mg 880120C-200mg 880120C-200mg 2 x 100mg 25mg/mL 4mL $370.00
500mg 880120C-500mg 880120C-500mg 1 x 500mg 25mg/mL 20mL $780.00

Powder

Size SKU Packaging Price
25mg 880120P-25mg 880120P-25mg 1 x 25mg $176.50 176.5
200mg 880120P-200mg 880120P-200mg 1 x 200mg $370.00 370
500mg 880120P-500mg 880120P-500mg 1 x 500mg $780.00 780
1g 880120P-1g 880120P-1g 1 x 1g $1,349.06 1349.06

Info

18:0 PEG2000 PE

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt)

Representative Structure

The formula weight and exact mass are averages based on the polydispersity of PEG.

PEG-modified lipids are typically added to phospholipid vesicles used for drug delivery to provide a steric coating on the surface of the membrane to hinder clearing of the particles by the reticuloendothelial system (RES). This prolongs the circulating plasma half-life of the drug. The plasma half-life of the drug can be "tuned" from several hours to days depending on the size of the PEG and fatty acids attached to the lipid anchor.

Data
Hygroscopic
Yes
Light Sensitive
No
Molecular Formula

C133H267N2O55P (average FW due to polydispersity of PEG)

Percent Composition

C 56.94%, H 9.59%, N 1.00%, O 31.36%, P 1.10%

Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
474922-77-5
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
2805.497
Exact Mass
2803.53
Synonyms
DSPE-mPEG(2000)

DSPE-PEG2000

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carbonyl-methoxy(polyethylene glycol)-2000] (ammonium salt)
Transition Temp
12.8°C (melting transition in micelles)
References

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Huang Y, Nan L, Xiao C, Ji Q, Li K, Wei Q, Liu Y, Bao G. Optimum Preparation Method for Self-Assembled PEGylation Nano-Adjuvant Based on Rehmannia glutinosa Polysaccharide and Its Immunological Effect on Macrophages. Int J Nanomedicine. 2019 Nov 29;14:9361-9375. doi: 10.2147/IJN.S221398. PMID: 31819437; PMCID: PMC6890198.

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Samaddar S, Mazur J, Boehm D, Thompson DH. Development And In Vitro Characterization Of Bladder Tumor Cell Targeted Lipid-Coated Polyplex For Dual Delivery Of Plasmids And Small Molecules. Int J Nanomedicine. 2019 Dec 4;14:9547-9561. doi: 10.2147/IJN.S225172. PMID: 31824150; PMCID: PMC6900316.

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Lee JY, Shin DH, Kim JS. Anticancer Effect of Metformin in Herceptin-Conjugated Liposome for Breast Cancer. Pharmaceutics. 2019 Dec 20;12(1):E11. doi: 10.3390/pharmaceutics12010011. PMID: 31877620.

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Gusti-Ngurah-Putu EP, Huang L, Hsu YC. Effective Combined Photodynamic Therapy with Lipid Platinum Chloride Nanoparticles Therapies of Oral Squamous Carcinoma Tumor Inhibition. J Clin Med. 2019 Dec 2;8(12):2112. doi: 10.3390/jcm8122112. PMID: 31810241; PMCID: PMC6947167.

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Fisher C, Obaid G, Niu C, Foltz W, Goldstein A, Hasan T, Lilge L. Liposomal Lapatinib in Combination with Low-Dose Photodynamic Therapy for the Treatment of Glioma. J Clin Med. 2019 Dec 14;8(12):2214. doi: 10.3390/jcm8122214. PMID: 31847378; PMCID: PMC6947404.

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Cho C, Jang J, Kang Y, Watanabe H, Uchihashi T, Kim SJ, Kato K, Lee JY, Song JJ. Structural basis of nucleosome assembly by the Abo1 AAA+ ATPase histone chaperone. Nat Commun. 2019 Dec 17;10(1):5764. doi: 10.1038/s41467-019-13743-9.

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Ye L, Hu R, Liu L, Liu J, Liu J, Chen H, Hu Y, Liu Y, Liu X, Liu C, Tng DJH, Meng Y, Qu J, Swihart MT, Yong KT. Comparing Semiconductor Nanocrystal Toxicity in Pregnant Mice and Non-Human Primates. Nanotheranostics. 2019 Jan 1;3(1):54-65. doi: 10.7150/ntno.27452. eCollection 2019.

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Melnikov PA, Valikhov MP, Kuznetsov II, Grinenko NF, Sukhinich KK, Simbirtsev AS, Kekelidze ZI, Chekhonin VP. Analysis of the Effect of IL-1β on Blood-Brain Barrier Permeability in M6 Glioma Mouse Model Using Intravital Microscopy. Bull Exp Biol Med. 2019 Nov 22. doi: 10.1007/s10517-019-04661-3. [Epub ahead of print]

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Wu M, Song Z, Zhang S, Dan Q, Tang C, Peng C, Liang Y, Zhang L, Wang H, Li Y. Local Tumor Ischemia-Reperfusion Mediated By Ultrasound-Targeted Microbubble Destruction Enhances The Anti-Tumor Efficacy Of Doxorubicin Chemotherapy. Cancer Manag Res. 2019 Nov 5;11:9387-9395. doi: 10.2147/CMAR.S225607. eCollection 2019.

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Cullion K, Petishnok LC, Ji T, Zurakowski D, Kohane DS. The Duration of Nerve Block from Local Anesthetic Formulations in Male and Female Rats. Pharm Res. 2019 Nov 8;36(12):179. doi: 10.1007/s11095-019-2715-3.

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Gallez A, Palazzo C, Blacher S, Tskitishvili E, Noël A, Foidart JM, Evrard B, Pequeux C, Piel G. Liposomes and drug-in-cyclodextrin-in-liposomes formulations encapsulating 17β-estradiol: An innovative drug delivery system that prevents the activation of the membrane-initiated steroid signaling (MISS) of estrogen receptor α. Int J Pharm. 2020 Jan 5;573:118861. doi: 10.1016/j.ijpharm.2019.118861. Epub 2019 Nov 22.

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Peng PC, Hong RL, Tsai T, Chen CT. Co-Encapsulation of Chlorin e6 and Chemotherapeutic Drugs in a PEGylated Liposome Enhance the Efficacy of Tumor Treatment: Pharmacokinetics and Therapeutic Efficacy. Pharmaceutics. 2019 Nov 17;11(11). pii: E617. doi: 10.3390/pharmaceutics11110617.

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Kulkarni JA, Witzigmann D, Leung J, Tam YYC, Cullis PR. On the role of helper lipids in lipid nanoparticle formulations of siRNA. Nanoscale. 2019 Nov 21;11(45):21733-21739. doi: 10.1039/c9nr09347h.

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Beguin E, Gray MD, Logan KA, Nesbitt H, Sheng Y, Kamila S, Barnsley LC, Bau L, McHale AP, Callan JF, Stride E. Magnetic microbubble mediated chemo-sonodynamic therapy using a combined magnetic-acoustic device. J Control Release. 2019 Nov 13;317:23-33. doi: 10.1016/j.jconrel.2019.11.013. [Epub ahead of print]

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Veiga N, Goldsmith M, Diesendruck Y, Ramishetti S, Rosenblum D, Elinav E, Behlke MA, Benhar I, Peer D. Leukocyte-specific siRNA delivery revealing IRF8 as a potential anti-inflammatory target. J Control Release. 2019 Oct 18;313:33-41. doi: 10.1016/j.jconrel.2019.10.001. [Epub ahead of print]

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Zheng Z, Ji H, Zong W, Ran Q, Wang X, Yang X, Zhao Z, Yang C, Xiao Y. Construction and characterization of immunoliposomes targeting fibroblast growth factor receptor 3. AMB Express. 2019 Sep 18;9(1):150. doi: 10.1186/s13568-019-0875-5.

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Chung CHY, Cui B, Song R, Liu X, Xu X, Yao S. Scalable Production of Monodisperse Functional Microspheres by Multilayer Parallelization of High Aspect Ratio Microfluidic Channels. Micromachines (Basel). 2019 Sep 10;10(9). pii: E592. doi: 10.3390/mi10090592.

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Guidi F, Supponen O, Upadhyay A, Vos HJ, Borden MA, Tortoli P. Microbubble radiation force-induced translation in plane-wave versus focused transmission modes. IEEE Trans Ultrason Ferroelectr Freq Control. 2019 Aug 23. doi: 10.1109/TUFFC.2019.2937158. [Epub ahead of print]

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Zhang X, Lin C, Chan W, Liu K, Lu A, Lin G, Hu R, Shi H, Zhang H, Yang Z. Dual-Functional Liposomes with Carbonic Anhydrase IX Antibody and BR2 Peptide Modification Effectively Improve Intracellular Delivery of Cantharidin to Treat Orthotopic Hepatocellular Carcinoma Mice. Molecules. 2019 Sep 12;24(18). pii: E3332. doi: 10.3390/molecules24183332.

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Shang H, Wu B, Liang X, Sun Y, Han X, Zhang L, Wang Q, Cheng W. Evaluation of therapeutic effect of targeting nanobubbles conjugated with NET-1 siRNA by shear wave elastography: an in vivo study of hepatocellular carcinoma bearing mice model. Drug Deliv. 2019 Dec;26(1):944-951. doi: 10.1080/10717544.2019.1667450.

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Abdurakman E, Bencsik M, Cave GWV, Hoad CL, McGowan S, Fairhurst DJ, Major G, Gowland PA, Bowtell R. Design and testing of microbubble-based MRI contrast agents for gastric pressure measurement. Magn Reson Med. 2019 Sep 16. doi: 10.1002/mrm.27992. [Epub ahead of print]

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Liu Y, Chen S, Sun J, Zhu S, Chen C, Xie W, Zheng J, Zhu Y, Xiao L, Hao L, Wang Z, Chang S. Folate-Targeted and Oxygen/Indocyanine Green-Loaded Lipid Nanoparticles for Dual-Mode Imaging and Photo-sonodynamic/Photothermal Therapy of Ovarian Cancer in Vitro and in Vivo. Mol Pharm. 2019 Oct 7;16(10):4104-4120. doi: 10.1021/acs.molpharmaceut.9b00339. Epub 2019 Sep 13.

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Kozlovskaya V, Liu F, Yang Y, Ingle K, Qian S, Halade GV, Urban VS, Kharlampieva E. Temperature-Responsive Polymersomes of Poly(3-methyl-N-vinylcaprolactam)-block-poly(N-vinylpyrrolidone) To Decrease Doxorubicin-Induced Cardiotoxicity. Biomacromolecules. 2019 Oct 14;20(10):3989-4000. doi: 10.1021/acs.biomac.9b01026. Epub 2019 Sep 24.

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Choi B, Soh M, Manandhar Y, Kim D, Han SI, Baik S, Shin K, Koo S, Kwon HJ, Ko G, Oh J, Hwang H, Hyeon T, Lee SJ. Highly selective microglial uptake of ceria-zirconia nanoparticles for enhanced analgesic treatment of neuropathic pain. Nanoscale. 2019 Sep 2. doi: 10.1039/c9nr02648g. [Epub ahead of print]

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Zhang D, Baldwin P, Leal AS, Carapellucci S, Sridhar S, Liby KT. A nano-liposome formulation of the PARP inhibitor Talazoparib enhances treatment efficacy and modulates immune cell populations in mammary tumors of BRCA-deficient mice. Theranostics. 2019 Aug 14;9(21):6224-6238. doi: 10.7150/thno.36281. eCollection 2019.

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Guevara ML, Jilesen Z, Stojdl D, Persano S. Codelivery of mRNA with α-Galactosylceramide Using a New Lipopolyplex Formulation Induces a Strong Antitumor Response upon Intravenous Administration. ACS Omega. 2019 Aug 7;4(8):13015-13026. doi: 10.1021/acsomega.9b00489. eCollection 2019 Aug 20.

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DeBoer MD. Assessing and Managing the Metabolic Syndrome in Children and Adolescents. Nutrients. 2019 Aug 2;11(8). pii: E1788. doi: 10.3390/nu11081788.

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Wang Z, Zhao K, Zhang Y, Duan X, Zhao Y. Anti-GPC3 Antibody Tagged Cationic Switchable Lipid-Based Nanoparticles for the Co-Delivery of Anti-miRNA27a And Sorafenib in Liver Cancers. Pharm Res. 2019 Aug 8;36(10):145. doi: 10.1007/s11095-019-2669-5.

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Fabio Vischio, Elisabetta Fanizza, Vito De Bellis, Teresa Sibillano, Chiara Ingrosso, Cinzia Giannini, Valentino Laquintana, Nunzio Denora, Angela Agostiano, Marinella Striccoli, M. Lucia Curri, and Nicoletta Depalo. Near-Infrared Absorbing Solid Lipid Nanoparticles Encapsulating Plasmonic Copper Sulfide Nanocrystals. J. Phys. Chem. C 2019, 123, 23205−23213


Zhou Q, Wang K, Dou J, Cao F, Liu F, Yuan H, Mu M, Xu J, Zhang D, Li X, Tian J, Yu J, Liang P. Theranostic liposomes as nanodelivered chemotherapeutics enhanced the microwave ablation of hepatocellular carcinoma. Nanomedicine (Lond). 2019 Aug;14(16):2151-2167. doi: 10.2217/nnm-2018-0424. Epub 2019 Aug 14.

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Ahmed G, Mackenzie GG, Egan J, Amiji MM. DHA-SBT-1214 Taxoid Nanoemulsion and Anti-PD-L1 Antibody Combination Therapy Enhances Anti-Tumor Efficacy in a Syngeneic Pancreatic Adenocarcinoma Model. Mol Cancer Ther. 2019 Aug 22. pii: molcanther.1046.2018. doi: 10.1158/1535-7163.MCT-18-1046. [Epub ahead of print]

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Shi D, Mi G, Shen Y, Webster TJ. Glioma-targeted dual functionalized thermosensitive Ferri-liposomes for drug delivery through an in vitro blood-brain barrier. Nanoscale. 2019 Aug 15;11(32):15057-15071. doi: 10.1039/c9nr03931g.

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Melo M, Porter E, Zhang Y, Silva M, Li N, Dobosh B, Liguori A, Skog P, Landais E, Menis S, Sok D, Nemazee D, Schief WR, Weiss R, Irvine DJ. Immunogenicity of RNA Replicons Encoding HIV Env Immunogens Designed for Self-Assembly into Nanoparticles. Mol Ther. 2019 Aug 19. pii: S1525-0016(19)30367-3. doi: 10.1016/j.ymthe.2019.08.007. [Epub ahead of print]

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Da Silva CG, Camps MGM, Li TMWY, Chan AB, Ossendorp F, Cruz LJ. Co-delivery of immunomodulators in biodegradable nanoparticles improves therapeutic efficacy of cancer vaccines. Biomaterials. 2019 Nov;220:119417. doi: 10.1016/j.biomaterials.2019.119417. Epub 2019 Aug 7.

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Binderup T, Duivenvoorden R, Fay F, van Leent MMT, Malkus J, Baxter S, Ishino S, Zhao Y, Sanchez-Gaytan B, Teunissen AJP, Frederico YCA, Tang J, Carlucci G, Lyashchenko S, Calcagno C, Karakatsanis N, Soultanidis G, Senders ML, Robson PM, Mani V, Ramachandran S, Lobatto ME, Hutten BA, Granada JF, Reiner T, Swirski FK, Nahrendorf M, Kjaer A, Fisher EA, Fayad ZA, Pérez-Medina C, Mulder WJM. Imaging-assisted nanoimmunotherapy for atherosclerosis in multiple species. Sci Transl Med. 2019 Aug 21;11(506). pii: eaaw7736. doi: 10.1126/scitranslmed.aaw7736.

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Ibaraki H, Kanazawa T, Kurano T, Oogi C, Takashima Y, Seta Y. Anti-RelA siRNA-Encapsulated Flexible Liposome with Tight Junction-Opening Peptide as a Non-invasive Topical Therapeutic for Atopic Dermatitis. Biol Pharm Bull. 2019;42(7):1216-1225. doi: 10.1248/bpb.b19-00259.

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Xu H, Chen B, Gong W, Yang Z, Qu J. Nanoliposomes Co-Encapsulating Photoswitchable Probe and Photosensitizer for Super-Resolution Optical Imaging and Photodynamic Therapy. Cytometry A. 2019 Jul 16. doi: 10.1002/cyto.a.23864. [Epub ahead of print]

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Meng L, Chu X, Xing H, Liu X, Xin X, Chen L, Jin M, Guan Y, Huang W, Gao Z. Improving glioblastoma therapeutic outcomes via doxorubicin-loaded nanomicelles modified with borneol. Int J Pharm. 2019 Aug 15;567:118485. doi: 10.1016/j.ijpharm.2019.118485. Epub 2019 Jun 29.

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Xie Y, Chen Y, Zhang L, Wu M, Deng Z, Yang Y, Wang J, Lv Q, Zheng H, Xie M, Yan F. Ultrasound Molecular Imaging of Lymphocyte-endothelium Adhesion Cascade in Acute Cellular Rejection of Cardiac Allografts. Transplantation. 2019 Aug;103(8):1603-1611. doi: 10.1097/TP.0000000000002698.

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Xiao Y, Liu Q, Clulow AJ, Li T, Manohar M, Gilbert EP, de Campo L, Hawley A, Boyd BJ. PEGylation and surface functionalization of liposomes containing drug nanocrystals for cell-targeted delivery. Colloids Surf B Biointerfaces. 2019 Jul 15;182:110362. doi: 10.1016/j.colsurfb.2019.110362. [Epub ahead of print]

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Kessenich BL, Pokhrel N, Nakouzi E, Newcomb CJ, Flury M, Maibaum L, De Yoreo JJ. Connecting wettability, topography, and chemistry in a simple lipid-montmorillonite system. J Colloid Interface Sci. 2019 Jul 26;555:498-508. doi: 10.1016/j.jcis.2019.07.075. [Epub ahead of print]

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Kim S, Sikes HD. Liposome-Enhanced Polymerization-Based Signal Amplification for Highly Sensitive Naked-Eye Biodetection in Paper-Based Sensors. ACS Appl Mater Interfaces. 2019 Aug 7;11(31):28469-28477. doi: 10.1021/acsami.9b08125. Epub 2019 Jul 26.

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Tucci ST, Kheirolomoom A, Ingham ES, Mahakian LM, Tam SM, Foiret J, Hubbard NE, Borowsky AD, Baikoghli M, Cheng RH, Ferrara KW. Tumor-specific delivery of gemcitabine with activatable liposomes. J Control Release. 2019 Jul 10. pii: S0168-3659(19)30401-8. doi: 10.1016/j.jconrel.2019.07.014. [Epub ahead of print]

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Yang X, Zhao J, Duan S, Hou X, Li X, Hu Z, Tang Z, Mo F, Lu X. Enhanced cytotoxic T lymphocytes recruitment targeting tumor vasculatures by endoglin aptamer and IP-10 plasmid presenting liposome-based nanocarriers. Theranostics. 2019 May 31;9(14):4066-4083. doi: 10.7150/thno.33383. eCollection 2019.

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Yao M, Elbayoumi T. Anionic and Cationic Vitamin E-TPGS Mixed Polymeric Phospholipid Micellar Vehicles. Methods Mol Biol. 2019;2000:31-41. doi: 10.1007/978-1-4939-9516-5_3.

PubMed ID: 31148006

Tunsirikongkon A, Pyo YC, Kim DH, Lee SE, Park JS. Optimization of Polyarginine-Conjugated PEG Lipid Grafted Proliposome Formulation for Enhanced Cellular Association of a Protein Drug. Pharmaceutics. 2019 Jun 11;11(6). pii: E272. doi: 10.3390/pharmaceutics11060272.

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Wang N, Qiu C, Chen M, Liu T, Wang T. Covering Aluminum Oxide Nanoparticles with Biocompatible Materials to Efficiently Deliver Subunit Vaccines. Vaccines (Basel). 2019 Jun 17;7(2). pii: E52. doi: 10.3390/vaccines7020052.

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Lim C, Kang JK, Won WR, Park JY, Han SM, Le TN, Kim JC, Her J, Shin Y, Oh KT. Co-delivery of D-(KLAKLAK)2 Peptide and Chlorin e6 using a Liposomal Complex for Synergistic Cancer Therapy. Pharmaceutics. 2019 Jun 21;11(6). pii: E293. doi: 10.3390/pharmaceutics11060293.

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Li N, Fu T, Fei W, Han T, Gu X, Hou Y, Liu Y, Yang J. Vitamin E D-alpha-tocopheryl polyethylene glycol 1000 succinate-conjugated liposomal docetaxel reverses multidrug resistance in breast cancer cells. J Pharm Pharmacol. 2019 Aug;71(8):1243-1254. doi: 10.1111/jphp.13126. Epub 2019 Jun 18.

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Nevozhay D, Weiger M, Friedl P, Sokolov KV. Spatiotemporally controlled nano-sized third harmonic generation agents. Biomed Opt Express. 2019 Jun 13;10(7):3301-3316. doi: 10.1364/BOE.10.003301. eCollection 2019 Jul 1.

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Shafi AS, McClements J, Albaijan I, Abou-Saleh RH, Moran C, Koutsos V. Probing phospholipid microbubbles by atomic force microscopy to quantify bubble mechanics and nanostructural shell properties. Colloids Surf B Biointerfaces. 2019 May 1;181:506-515. doi: 10.1016/j.colsurfb.2019.04.062. [Epub ahead of print]

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Yan Y, Li XQ, Duan JL, Bao CJ, Cui YN, Su ZB, Xu JR, Luo Q, Chen M, Xie Y, Lu WL. Nanosized functional miRNA liposomes and application in the treatment of TNBC by silencing Slug gene. Int J Nanomedicine. 2019 May 17;14:3645-3667. doi: 10.2147/IJN.S207837. eCollection 2019.

PubMed ID: 31190817

Marazioti A, Papadia K, Giannou A, Stathopoulos GT, Antimisiaris SG. Prolonged retention of liposomes in the pleural cavity of normal mice and high tumor distribution in mice with malignant pleural effusion, after intrapleural injection. Int J Nanomedicine. 2019 May 23;14:3773-3784. doi: 10.2147/IJN.S202568. eCollection 2019.

PubMed ID: 31213801

Khan MW, Zhao P, Khan A, Raza F, Raza SM, Sarfraz M, Chen Y, Li M, Yang T, Ma X, Xiang G. Synergism of cisplatin-oleanolic acid co-loaded calcium carbonate nanoparticles on hepatocellular carcinoma cells for enhanced apoptosis and reduced hepatotoxicity. Int J Nanomedicine. 2019 May 28;14:3753-3771. doi: 10.2147/IJN.S196651. eCollection 2019.

PubMed ID: 31239661

Huang Y, Huang Y, He J, Wang H, Luo Y, Li Y, Liu J, Zhong L, Zhao Y. PEGylated immunoliposome-loaded endoglin single-chain antibody enhances anti-tumor capacity of porcine α1,3GT gene. Biomaterials. 2019 Oct;217:119231. doi: 10.1016/j.biomaterials.2019.119231. Epub 2019 Jun 14.

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Wu D, Jin X, Wang X, Ma B, Lou C, Qu H, Zheng J, Zhang B, Yan X, Wang Y, Jing L. Engineering temperature-sensitive plateletsomes as a tailored chemotherapy platform in combination with HIFU ablation for cancer treatment. Theranostics. 2019 May 31;9(13):3966-3979. doi: 10.7150/thno.32172. eCollection 2019.

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Baldwin P, Ohman AW, Medina JE, McCarthy ET, Dinulescu DM, Sridhar S. Nanoformulation of Talazoparib Delays Tumor Progression and Ascites Formation in a Late Stage Cancer Model. Front Oncol. 2019 May 10;9:353. doi: 10.3389/fonc.2019.00353. eCollection 2019.

PubMed ID: 31134152

Marazioti A, Papadia K, Kannavou M, Spella M, Basta A, de Lastic AL, Rodi M, Mouzaki A, Samiotaki M, Panayotou G, Stathopoulos GT, Antimisiaris SG. Cellular Vesicles: New insights in engineering methods, interaction with cells and potential for brain targeting. J Pharmacol Exp Ther. 2019 May 6. pii: jpet.119.257097. doi: 10.1124/jpet.119.257097. [Epub ahead of print]

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Schmidt ST, Olsen CL, Franzyk H, Wørzner K, Korsholm KS, Rades T, Andersen P, Foged C, Christensen D. Comparison of two different PEGylation strategies for the liposomal adjuvant CAF09: Towards induction of CTL responses upon subcutaneous vaccine administration. Eur J Pharm Biopharm. 2019 Jul;140:29-39. doi: 10.1016/j.ejpb.2019.04.020. Epub 2019 May 2.

PubMed ID: 31055066

Vlasova KY, Piroyan A, Le-Deygen IM, Vishwasrao HM, Ramsey JD, Klyachko NL, Golovin YI, Rudakovskaya PG, Kireev II, Kabanov AV, Sokolsky-Papkov M. Magnetic liposome design for drug release systems responsive to super-low frequency alternating current magnetic field (AC MF). J Colloid Interface Sci. 2019 May 23;552:689-700. doi: 10.1016/j.jcis.2019.05.071. [Epub ahead of print]

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Song J, Zhang N, Zhang L, Yi H, Liu Y, Li Y, Li X, Wu M, Hao L, Yang Z, Wang Z. IR780-loaded folate-targeted nanoparticles for near-infrared fluorescence image-guided surgery and photothermal therapy in ovarian cancer. Int J Nanomedicine. 2019 Apr 18;14:2757-2772. doi: 10.2147/IJN.S203108. eCollection 2019.

PubMed ID: 31118609

Riaz MK, Zhang X, Wong KH, Chen H, Liu Q, Chen X, Zhang G, Lu A, Yang Z. Pulmonary delivery of transferrin receptors targeting peptide surface-functionalized liposomes augments the chemotherapeutic effect of quercetin in lung cancer therapy. Int J Nanomedicine. 2019 Apr 24;14:2879-2902. doi: 10.2147/IJN.S192219. eCollection 2019.

PubMed ID: 31118613

Lorscheider M, Tsapis N, Simón-Vázquez R, Guiblin N, Ghermani N, Reynaud F, Canioni R, Abreu S, Chaminade P, Fattal E. Nanoscale Lipophilic Prodrugs of Dexamethasone with Enhanced Pharmacokinetics. Mol Pharm. 2019 Jul 1;16(7):2999-3010. doi: 10.1021/acs.molpharmaceut.9b00237. Epub 2019 Jun 4.

PubMed ID: 31117740

Giannakou C, Aimonen K, Bloois LV, Catalán J, Geertsma RE, Gremmer ER, de Jong WH, Keizers PH, Schwillens PL, Vandebriel RJ, Park MV. Sensitive method for endotoxin determination in nanomedicinal product samples. Nanomedicine (Lond). 2019 May;14(10):1231-1246. doi: 10.2217/nnm-2018-0339.

PubMed ID: 31124759

Shekhar H, Palaniappan A, Peng T, Lafond M, Moody MR, Haworth KJ, Huang S, McPherson DD, Holland CK. Characterization and Imaging of Lipid-Shelled Microbubbles for Ultrasound-Triggered Release of Xenon. Neurotherapeutics. 2019 Apr 24. doi: 10.1007/s13311-019-00733-4. [Epub ahead of print]

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Song J, Zhang L, Yi H, Huang J, Zhang N, Zhong Y, Hao L, Ke Yang, Wang Z, Wang D, Yang Z. NIR-responsive nanoplatform for pre/intraoperative image-guided carcinoma surgery and photothermal ablation of residual tumor tissue. Nanomedicine. 2019 May 22;20:102020. doi: 10.1016/j.nano.2019.102020. [Epub ahead of print]

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Baglo Y, Liang BJ, Robey RW, Ambudkar SV, Gottesman MM, Huang HC. Porphyrin-lipid assemblies and nanovesicles overcome ABC transporter-mediated photodynamic therapy resistance in cancer cells. Cancer Lett. 2019 Aug 10;457:110-118. doi: 10.1016/j.canlet.2019.04.037. Epub 2019 May 6.

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Tang J, Li B, Howard CB, Mahler SM, Thurecht KJ, Wu Y, Huang L, Xu ZP. Multifunctional lipid-coated calcium phosphate nanoplatforms for complete inhibition of large triple negative breast cancer via targeted combined therapy. Biomaterials. 2019 May 31;216:119232. doi: 10.1016/j.biomaterials.2019.119232. [Epub ahead of print]

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Yarmoska SK, Yoon H, Emelianov SY. Lipid Shell Composition Plays a Critical Role in the Stable Size Reduction of Perfluorocarbon Nanodroplets. Ultrasound Med Biol. 2019 Jun;45(6):1489-1499. doi: 10.1016/j.ultrasmedbio.2019.02.009. Epub 2019 Apr 8.

PubMed ID: 30975536

Fix SM, Koppolu BP, Novell A, Hopkins J, Kierski TM, Zaharoff DA, Dayton PA, Papadopoulou V. Ultrasound-Stimulated Phase-Change Contrast Agents for Transepithelial Delivery of Macromolecules, Toward Gastrointestinal Drug Delivery. Ultrasound Med Biol. 2019 Jul;45(7):1762-1776. doi: 10.1016/j.ultrasmedbio.2019.02.004. Epub 2019 Apr 16.

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Mohanty K, Papadopoulou V, Newsome IG, Shelton S, Dayton PA, Muller M. Ultrasound multiple scattering with microbubbles can differentiate between tumor and healthy tissue in vivo. Phys Med Biol. 2019 May 31;64(11):115022. doi: 10.1088/1361-6560/ab1a44.

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Mourtas S, Christodoulou P, Klepetsanis P, Gatos D, Barlos K, Antimisiaris SG. Preparation of Benzothiazolyl-Decorated Nanoliposomes. Molecules. 2019 Apr 18;24(8). pii: E1540. doi: 10.3390/molecules24081540.

PubMed ID: 31003552

Michanetzis GP, Markoutsa E, Mourtas S, Missirlis YF, Antimisiaris SG. Hemocompatibility of amyloid and/or brain targeted liposomes. Future Med Chem. 2019 Apr;11(7):693-705. doi: 10.4155/fmc-2018-0236. Epub 2019 Apr 9.

PubMed ID: 30964329

Shuoye Yang, Shibo Song, Kaishuo Han, Xingwang Wu, Lingzhi Chen, Yuansen Hu, Jinshui Wang, Bin Liu. Characterization, in vitro evaluation and comparative study on the cellular internalization of mesoporous silica nanoparticle-supported lipid bilayers. Microporous and Mesoporous Materials. 2019 August;284:212-224. doi: 10.1016/j.micromeso.2019.04.043


Kinoshita T, Ujiie H, Chen J, Ding L, Chan H, Gregor A, Bernards N, McVeigh PZ, Fujino K, Lee CY, Motooka Y, Inage T, Valic MS, Effat A, Weersink R, Wilson BC, Zheng G, Asamura H, Yasufuku K. Evaluation of Novel Imaging Devices for Nanoparticle-Mediated Fluorescence-Guided Lung Tumor Therapy. Ann Thorac Surg. 2019 Feb 8. pii: S0003-4975(19)30184-5. doi: 10.1016/j.athoracsur.2019.01.008. [Epub ahead of print]

PubMed ID: 30742818

Logan K, Foglietta F, Nesbitt H, Sheng Y, McKaig T, Kamila S, Gao J, Nomikou N, Callan B, McHale AP, Callan JF. Targeted chemo-sonodynamic therapy treatment of breast tumours using ultrasound responsive microbubbles loaded with paclitaxel, doxorubicin and Rose Bengal. Eur J Pharm Biopharm. 2019 Jun;139:224-231. doi: 10.1016/j.ejpb.2019.04.003. Epub 2019 Apr 5.

PubMed ID: 30959180

Gao X, Zou W, Jiang B, Xu D, Luo Y, Xiong J, Yan S, Wang Y, Tang Y, Chen C, Li H, Qiao H, Wang Q, Zou J. Experimental Study of Retention on the Combination of Bifidobacterium with High-Intensity Focused Ultrasound (HIFU) Synergistic Substance in Tumor Tissues. Sci Rep. 2019 Apr 23;9(1):6423. doi: 10.1038/s41598-019-42832-4.

PubMed ID: 31015517

So PW, Ekonomou A, Galley K, Brody L, Sahuri-Arisoylu M, Rattray I, Cash D, Bell JD. Intraperitoneal delivery of acetate-encapsulated liposomal nanoparticles for neuroprotection of the penumbra in a rat model of ischemic stroke. Int J Nanomedicine. 2019 Mar 18;14:1979-1991. doi: 10.2147/IJN.S193965. eCollection 2019.

PubMed ID: 30936698

Shen Y, Lv W, Yang H, Cai W, Zhao P, Zhang L, Zhang J, Yuan L, Duan Y. FA-NBs-IR780: Novel multifunctional nanobubbles as molecule-targeted ultrasound contrast agents for accurate diagnosis and photothermal therapy of cancer. Cancer Lett. 2019 Jul 28;455:14-25. doi: 10.1016/j.canlet.2019.04.023. Epub 2019 Apr 21.

PubMed ID: 31018151

Zhou B, Jiang Q, Xiao X, Xu X, Xu Y, Kong Y, Zhang W, Zeng Y, Liu X, Luo B. Assisting anti-PD-1 antibody treatment with a liposomal system capable of recruiting immune cells. Nanoscale. 2019 Apr 23;11(16):7996-8011. doi: 10.1039/c9nr01434a.

PubMed ID: 30969294

Kulkarni JA, Witzigmann D, Leung J, van der Meel R, Zaifman J, Darjuan MM, Grisch-Chan HM, Thöny B, Tam YYC, Cullis PR. Fusion-dependent formation of lipid nanoparticles containing macromolecular payloads. Nanoscale. 2019 May 9;11(18):9023-9031. doi: 10.1039/c9nr02004g.

PubMed ID: 31021343

Wang P, Wu W, Gao R, Zhu H, Wang J, Du R, Li X, Zhang C, Cao S, Xiang R. Engineered Cell-Assisted Photoactive Nanoparticle Delivery for Image-Guided Synergistic Photodynamic/Photothermal Therapy of Cancer. ACS Appl Mater Interfaces. 2019 Apr 17;11(15):13935-13944. doi: 10.1021/acsami.9b00022. Epub 2019 Apr 4.

PubMed ID: 30915833

Kheirolomoom A, Silvestrini MT, Ingham ES, Mahakian LM, Tam SM, Tumbale SK, Foiret J, Hubbard NE, Borowsky AD, Ferrara KW. Combining activatable nanodelivery with immunotherapy in a murine breast cancer model. J Control Release. 2019 Apr 9;303:42-54. doi: 10.1016/j.jconrel.2019.04.008. [Epub ahead of print]

PubMed ID: 30978432

Deak PE, Kim B, Abdul Qayum A, Shin J, Vitalpur G, Kloepfer KM, Turner MJ, Smith N, Shreffler WG, Kiziltepe T, Kaplan MH, Bilgicer B. Designer covalent heterobivalent inhibitors prevent IgE-dependent responses to peanut allergen. Proc Natl Acad Sci U S A. 2019 Apr 30;116(18):8966-8974. doi: 10.1073/pnas.1820417116. Epub 2019 Apr 8.

PubMed ID: 30962381

Duan X, Chan C, Han W, Guo N, Weichselbaum RR, Lin W. Immunostimulatory nanomedicines synergize with checkpoint blockade immunotherapy to eradicate colorectal tumors. Nat Commun. 2019 Apr 23;10(1):1899. doi: 10.1038/s41467-019-09221-x.

PubMed ID: 31015397

Erel-Akbaba G, Carvalho LA, Tian T, Zinter M, Akbaba H, Obeid PJ, Chiocca EA, Weissleder R, Kantarci AG, Tannous BA. Radiation-Induced Targeted Nanoparticle-Based Gene Delivery for Brain Tumor Therapy. ACS Nano. 2019 Apr 23;13(4):4028-4040. doi: 10.1021/acsnano.8b08177. Epub 2019 Mar 27.

PubMed ID: 30916923

Akhtari J, Faridnia R, Kalani H, Bastani R, Fakhar M, Rezvan H, Beydokhti AK. Potent in vitro antileishmanial activity of a nanoformulation of cisplatin with carbon nanotubes against Leishmania major. J Glob Antimicrob Resist. 2019 Mar;16:11-16. doi: 10.1016/j.jgar.2018.09.004. Epub 2018 Sep 20.

PubMed ID: 30244039

Yari H, Nkepang G, Awasthi V. Surface Modification of Liposomes by a Lipopolymer Targeting Prostate Specific Membrane Antigen for Theranostic Delivery in Prostate Cancer. Materials (Basel). 2019 Mar 5;12(5). pii: E756. doi: 10.3390/ma12050756.

PubMed ID: 30841602

Yongchao Zhang, Zhenfen Tian, Xiaotong Zhao, Na Li, Vasil M. Garamus, Peihao Yin, Aihua Zou. Dual-modified bufalin loaded liposomes for enhanced tumor targeting. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 2019 June 20;571:72-79. doi: 10.1016/j.colsurfa.2019.03.060


Arana L, Bayón-Cordero L, Sarasola LI, Berasategi M, Ruiz S, Alkorta I. Solid Lipid Nanoparticles Surface Modification Modulates Cell Internalization and Improves Chemotoxic Treatment in an Oral Carcinoma Cell Line. Nanomaterials (Basel). 2019 Mar 20;9(3). pii: E464. doi: 10.3390/nano9030464.

PubMed ID: 30897724

Maqbool F, Moyle PM, Thurecht KJ, Falconer JR. Dispersibility of phospholipids and their optimization for the efficient production of liposomes using supercritical fluid technology. Int J Pharm. 2019 Mar 30;563:174-183. doi: 10.1016/j.ijpharm.2019.03.053. [Epub ahead of print]

PubMed ID: 30940503

Abou-Saleh RH, McLaughlan JR, Bushby RJ, Johnson BR, Freear S, Evans SD, Thomson NH. Molecular Effects of Glycerol on Lipid Monolayers at the Gas-Liquid Interface: Impact on Microbubble Physical and Mechanical Properties. Langmuir. 2019 Apr 5. doi: 10.1021/acs.langmuir.8b04130. [Epub ahead of print]

PubMed ID: 30901226

Bohley M, Haunberger A, Goepferich AM. Intracellular availability of poorly soluble drugs from lipid nanocapsules. Eur J Pharm Biopharm. 2019 Mar 6. pii: S0939-6411(18)31530-3. doi: 10.1016/j.ejpb.2019.03.007. [Epub ahead of print]

PubMed ID: 30851353

Derbali RM, Aoun V, Moussa G, Frei G, Tehrani SF, Del'Orto JC, Hildgen P, Roullin VG, Chain JL. Tailored Nanocarriers for the Pulmonary Delivery of Levofloxacin against Pseudomonas aeruginosa: A Comparative Study. Mol Pharm. 2019 Apr 4. doi: 10.1021/acs.molpharmaceut.8b01256. [Epub ahead of print]

PubMed ID: 30900903

Pinho JO, Amaral JD, Castro RE, Rodrigues CM, Casini A, Soveral G, Gaspar MM. Copper complex nanoformulations featuring highly promising therapeutic potential in murine melanoma models. Nanomedicine (Lond). 2019 Apr;14(7):835-850. doi: 10.2217/nnm-2018-0388. Epub 2019 Mar 15.

PubMed ID: 30875274

Xu G, Qian Y, Zheng H, Qiao S, Yan D, Lu L, Wu L, Yang X, Luo Q, Zhang Z. Long-Distance Tracing of the Lymphatic System with a Computed Tomography/Fluorescence Dual-Modality Nanoprobe for Surveying Tumor Lymphatic Metastasis. Bioconjug Chem. 2019 Apr 17;30(4):1199-1209. doi: 10.1021/acs.bioconjchem.9b00144. Epub 2019 Apr 1.

PubMed ID: 30888794

Bednar KJ, Nycholat CM, Rao TS, Paulson JC, Fung-Leung WP, Macauley MS. Exploiting CD22 To Selectively Tolerize Autoantibody Producing B-Cells in Rheumatoid Arthritis. ACS Chem Biol. 2019 Apr 19;14(4):644-654. doi: 10.1021/acschembio.8b01018. Epub 2019 Mar 20.

PubMed ID: 30835424

Xu H, Ohulchanskyy TY, Yakovliev A, Zinyuk R, Song J, Liu L, Qu J, Yuan Z. Nanoliposomes Co-Encapsulating CT Imaging Contrast Agent and Photosensitizer for Enhanced, Imaging Guided Photodynamic Therapy of Cancer. Theranostics. 2019 Feb 12;9(5):1323-1335. doi: 10.7150/thno.31079. eCollection 2019.

PubMed ID: 30867833

Kim B, Pena CD, Auguste DT. Targeted Lipid Nanoemulsions Encapsulating Epigenetic Drugs Exhibit Selective Cytotoxicity on CDH1-/FOXM1+ Triple Negative Breast Cancer Cells. Mol Pharm. 2019 Mar 29. doi: 10.1021/acs.molpharmaceut.8b01065. [Epub ahead of print]

PubMed ID: 30883132

Mine Silindir-Gunay, Merve Karpuz, Naile Ozturk, A.Yekta Ozer, Suna Erdogan, Murat Tuncel. Radiolabeled, folate-conjugated liposomes as tumor imaging agents: Formulation and in vitro evaluation. Journal of Drug Delivery Science and Technology. 2019 April;50:321-328. doi: 10.1016/j.jddst.2019.02.003


Yücel Ç, Altintaş Y, Değim Z, Yılmaz Ş, Arsoy T, Altıntaş L, Çokçalışkan C, Sözmen M. Novel Approach to the Treatment of Diabetes: Embryonic Stem Cell and Insulin-Loaded Liposomes and Nanocochleates. J Nanosci Nanotechnol. 2019 Jul 1;19(7):3706-3719. doi: 10.1166/jnn.2019.16321.

PubMed ID: 30764927

Zheng T, Feng H, Liu L, Peng J, Xiao H, Yu T, Zhou Z, Li Y, Zhang Y, Bai X, Zhao S, Shi Y, Chen Y. Enhanced antiproliferative effect of resveratrol in head and neck squamous cell carcinoma using GE11 peptide conjugated liposome. Int J Mol Med. 2019 Feb 13. doi: 10.3892/ijmm.2019.4096. [Epub ahead of print]

PubMed ID: 30816515

Rojas JD, Dayton PA. In Vivo Molecular Imaging Using Low-Boiling-Point Phase-Change Contrast Agents: A Proof of Concept Study. Ultrasound Med Biol. 2019 Jan;45(1):177-191. doi: 10.1016/j.ultrasmedbio.2018.08.004. Epub 2018 Oct 11.

PubMed ID: 30318123

Zhang G, Lin S, Leow CH, Pang KT, Hernández-Gil J, Long NJ, Eckersley R, Matsunaga T, Tang MX. Quantification of Vaporised Targeted Nanodroplets Using High-Frame-Rate Ultrasound and Optics. Ultrasound Med Biol. 2019 Feb 28. pii: S0301-5629(19)30018-3. doi: 10.1016/j.ultrasmedbio.2019.01.009. [Epub ahead of print]

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Abdelrehim A, Shaltiel L, Zhang L, Barenholz Y, High S, Harris LK. The use of tail-anchored protein chimeras to enhance liposomal cargo delivery. PLoS One. 2019 Feb 22;14(2):e0212701. doi: 10.1371/journal.pone.0212701. eCollection 2019.

PubMed ID: 30794671

Xinyu Cui, Wenlong Cheng, Mingdong Dong, and Xiaojun Han. A multifunctional biomimetic hybrid nanocarrier for the controlled delivery of chemotherapy drugs by near-infrared light. New J. Chem., 2019, 43, 2752-2757. doi: 10.1039/C8NJ05879B


Gomes FO, Maia LB, Loureiro JA, Pereira MC, Delerue-Matos C, Moura I, Moura JJG, Morais S. Biosensor for direct bioelectrocatalysis detection of nitric oxide using nitric oxide reductase incorporated in carboxylated single-walled carbon nanotubes/lipidic 3 bilayer nanocomposite. Bioelectrochemistry. 2019 Feb 5;127:76-86. doi: 10.1016/j.bioelechem.2019.01.010. [Epub ahead of print]

PubMed ID: 30745281

Jing Y, Xiu-Juan Z, Hong-Jiao C, Zhi-Kui C, Qing-Fu Q, En-Sheng X, Li-Wu L. Ultrasound-targeted microbubble destruction improved the antiangiogenic effect of Endostar in triple-negative breast carcinoma xenografts. J Cancer Res Clin Oncol. 2019 Feb 25. doi: 10.1007/s00432-019-02866-7. [Epub ahead of print]

PubMed ID: 30805775

Feng C, Zhang H, Chen J, Wang S, Xin Y, Qu Y, Zhang Q, Ji W, Yamashita F, Rui M, Xu X. Ratiometric co-encapsulation and co-delivery of doxorubicin and paclitaxel by tumor-targeted lipodisks for combination therapy of breast cancer. Int J Pharm. 2019 Apr 5;560:191-204. doi: 10.1016/j.ijpharm.2019.02.009. Epub 2019 Feb 12.

PubMed ID: 30769131

Palazzo C, Laloy J, Delvigne AS, Nys G, Fillet M, Dogne JM, Pequeux C, Foidart JM, Evrard B, Piel G. Development of injectable liposomes and drug-in-cyclodextrin-in-liposome formulations encapsulating estetrol to prevent cerebral ischemia of premature babies. Eur J Pharm Sci. 2019 Jan 15;127:52-59. doi: 10.1016/j.ejps.2018.10.006. Epub 2018 Oct 9.

PubMed ID: 30308312

Gormley CA, Keenan BJ, Buczek-Thomas JA, Pessoa ACSN, Xu J, Monti F, Tabeling P, Holt RG, Nagy JO, Wong JY. Fibrin-Targeted Polymerized Shell Microbubbles as Potential Theranostic Agents for Surgical Adhesions. Langmuir. 2019 Feb 8. doi: 10.1021/acs.langmuir.8b03692. [Epub ahead of print]

PubMed ID: 30681875

Viitala L, Pajari S, Gentile L, Määttä J, Gubitosi M, Deska J, Sammalkorpi M, Olsson U, Murtomäki L. Shape and Phase Transitions in a PEGylated Phospholipid System. Langmuir. 2019 Mar 19;35(11):3999-4010. doi: 10.1021/acs.langmuir.8b03829. Epub 2019 Mar 7.

PubMed ID: 30789270

Cheng Y, Zou T, Dai M, He XY, Peng N, Wu K, Wang XQ, Liao CY, Liu Y. Doxorubicin loaded tumor-triggered targeting ammonium bicarbonate liposomes for tumor-specific drug delivery. Colloids Surf B Biointerfaces. 2019 Mar 2;178:263-268. doi: 10.1016/j.colsurfb.2019.03.002. [Epub ahead of print]

PubMed ID: 30877911

Nguyen VD, Min HK, Kim CS, Han J, Park JO, Choi E. Folate receptor-targeted liposomal nanocomplex for effective synergistic photothermal-chemotherapy of breast cancer in vivo. Colloids Surf B Biointerfaces. 2019 Jan 1;173:539-548. doi: 10.1016/j.colsurfb.2018.10.013. Epub 2018 Oct 9.

PubMed ID: 30343218

Thakur SS, Chen YS, Houston ZH, Fletcher N, Barnett NL, Thurecht KJ, Rupenthal ID, Parekh HS. Ultrasound-responsive nanobubbles for enhanced intravitreal drug migration: An ex vivo evaluation. Eur J Pharm Biopharm. 2019 Mar;136:102-107. doi: 10.1016/j.ejpb.2019.01.014. Epub 2019 Jan 17.

PubMed ID: 30660691

Wan F, Nylander T, Foged C, Yang M, Baldursdottir SG, Nielsen HM. Qualitative and quantitative analysis of the biophysical interaction of inhaled nanoparticles with pulmonary surfactant by using quartz crystal microbalance with dissipation monitoring. J Colloid Interface Sci. 2019 Mar 1;545:162-171. doi: 10.1016/j.jcis.2019.02.088. [Epub ahead of print]

PubMed ID: 30877998

Stefanick JF, Omstead DT, Kiziltepe T, Bilgicer B. Dual-receptor targeted strategy in nanoparticle design achieves tumor cell selectivity through cooperativity. Nanoscale. 2019 Mar 7;11(10):4414-4427. doi: 10.1039/c8nr09431d.

PubMed ID: 30801591

Tahmasbi Rad A, Chen CW, Aresh W, Xia Y, Lai PS, Nieh MP. Combinational Effects of Active Targeting, Shape, and Enhanced Permeability and Retention for Cancer Theranostic Nanocarriers. ACS Appl Mater Interfaces. 2019 Mar 20;11(11):10505-10519. doi: 10.1021/acsami.8b21609. Epub 2019 Mar 11.

PubMed ID: 30793580

Deshantri AK, Fens MH, Ruiter RWJ, Metselaar JM, Storm G, van Bloois L, Varela-Moreira A, Mandhane SN, Mutis T, Martens ACM, Groen RWJ, Schiffelers RM. Liposomal dexamethasone inhibits tumor growth in an advanced human-mouse hybrid model of multiple myeloma. J Control Release. 2019 Feb 28;296:232-240. doi: 10.1016/j.jconrel.2019.01.028. Epub 2019 Jan 22.

PubMed ID: 30682443

Tabatabaei SN, Derbali RM, Yang C, Superstein R, Hamel P, Chain JL, Hardy P. Co-delivery of miR-181a and melphalan by lipid nanoparticles for treatment of seeded retinoblastoma. J Control Release. 2019 Mar 28;298:177-185. doi: 10.1016/j.jconrel.2019.02.014. Epub 2019 Feb 15.

PubMed ID: 30776396

Zhang Y, Bush X, Yan B, Chen JA. Gemcitabine nanoparticles promote antitumor immunity against melanoma. Biomaterials. 2019 Jan;189:48-59. doi: 10.1016/j.biomaterials.2018.10.022. Epub 2018 Oct 20.

PubMed ID: 30388589

Kim MW, Jeong HY, Kang SJ, Jeong IH, Choi MJ, You YM, Im CS, Song IH, Lee TS, Lee JS, Lee A, Park YS. Anti-EGF Receptor Aptamer-Guided Co-Delivery of Anti-Cancer siRNAs and Quantum Dots for Theranostics of Triple-Negative Breast Cancer. Theranostics. 2019 Jan 25;9(3):837-852. doi: 10.7150/thno.30228. eCollection 2019.

PubMed ID: 30809312

Song, R., Peng, C., Xu, X. et al. Microfluid Nanofluid (2019) 23: 12. doi: 10.1007/s10404-018-2172-z


Keller S, Bruce M, Averkiou MA. Ultrasound Imaging of Microbubble Activity during Sonoporation Pulse Sequences. Ultrasound Med Biol. 2019 Mar;45(3):833-845. doi: 10.1016/j.ultrasmedbio.2018.11.011. Epub 2019 Jan 9.

PubMed ID: 30638695

Burgess MT, Porter TM. Control of Acoustic Cavitation for Efficient Sonoporation with Phase-Shift Nanoemulsions. Ultrasound Med Biol. 2019 Mar;45(3):846-858. doi: 10.1016/j.ultrasmedbio.2018.12.001. Epub 2019 Jan 11.

PubMed ID: 30638968

Xinyu Cui, Wenlong Cheng, Mingdong Dong, and Xiaojun Han. A multifunctional biomimetic hybrid nanocarrier for the controlled delivery of chemotherapy drugs by near-infrared light. New J. Chem., 2019,43, 2752-2757. doi: 10.1039/C8NJ05879B


Li M, Yang Y, Xu C, Wei J, Liu Y, Cun X, Yu Q, Tang X, Yin S, Zhang Z, He Q. Tumor-Targeted Chemoimmunotherapy with Immune-Checkpoint Blockade for Enhanced Anti-Melanoma Efficacy. AAPS J. 2019 Jan 11;21(2):18. doi: 10.1208/s12248-018-0289-3.

PubMed ID: 30635795

Kumar P, Pletzer D, Haney EF, Rahanjam N, Cheng JTJ, Yue M, Aljehani W, Hancock REW, Kizhakkedathu JN, Straus SK. Aurein-Derived Antimicrobial Peptides Formulated with Pegylated Phospholipid Micelles to Target Methicillin-Resistant Staphylococcus aureus Skin Infections. ACS Infect Dis. 2019 Mar 8;5(3):443-453. doi: 10.1021/acsinfecdis.8b00319. Epub 2019 Jan 2.

PubMed ID: 30565465

Nemoto R, Fujieda K, Hiruta Y, Hishida M, Ayano E, Maitani Y, Nagase K, Kanazawa H. Liposomes with temperature-responsive reversible surface properties. Colloids Surf B Biointerfaces. 2019 Jan 3;176:309-316. doi: 10.1016/j.colsurfb.2019.01.007. [Epub ahead of print]

PubMed ID: 30641302

Viitala L, Pajari S, Gentile L, Määttä J, Gubitosi M, Deska J, Sammalkorpi M, Olsson U, Murtomäki L. Shape and Phase Transitions in a PEGylated Phospholipid System. Langmuir. 2019 Feb 21. doi: 10.1021/acs.langmuir.8b03829. [Epub ahead of print]

PubMed ID: 30789270

Song Y, Sheng Z, Xu Y, Dong L, Xu W, Li F, Wang J, Wu Z, Yang Y, Su Y, Sun X, Ling D, Lu Y. Magnetic liposomal emodin composite with enhanced killing efficiency against breast cancer. Biomater Sci. 2019 Feb 26;7(3):867-875. doi: 10.1039/c8bm01530a.

PubMed ID: 30648710

Andersen MN, Etzerodt A, Graversen JH, Holthof LC, Moestrup SK, Hokland M, Møller HJ. STAT3 inhibition specifically in human monocytes and macrophages by CD163-targeted corosolic acid-containing liposomes. Cancer Immunol Immunother. 2019 Jan 14. doi: 10.1007/s00262-019-02301-3. [Epub ahead of print]

PubMed ID: 30637473

Chen M, Song F, Liu Y, Tian J, Liu C, Li R, Zhang Q. A dual pH-sensitive liposomal system with charge-reversal and NO generation for overcoming multidrug resistance in cancer. Nanoscale. 2019 Mar 7;11(9):3814-3826. doi: 10.1039/c8nr06218h. Epub 2019 Jan 2.

PubMed ID: 30600823

Bi-Hua Lv, Wei Tan, Xuejun Shang, Ling Zhang. Evaluation of clinical effectiveness of paclitaxel and ursolic acid co-loaded liposomes as enhanced treatment for head and neck squamous cell carcinoma. Tropical Journal of Pharmaceutical Research November 2018; 17 (11): 2115-2121. doi: 10.4314/tjpr.v17i11.1


Zhao R, Jiang J, Li H, Chen M, Liu R, Sun S, Ma, Liang X, Wang S. Phosphatidylserine-microbubble targeting-activated microglia/macrophage in inflammation combined with ultrasound for breaking through the blood-brain barrier. J Neuroinflammation. 2018 Nov 30;15(1):334. doi: 10.1186/s12974-018-1368-1.

PubMed ID: 30501630

Poon C, Gallo J, Joo J, Chang T, Bañobre-López M, Chung EJ. Hybrid, metal oxide-peptide amphiphile micelles for molecular magnetic resonance imaging of atherosclerosis. J Nanobiotechnology. 2018 Nov 15;16(1):92. doi: 10.1186/s12951-018-0420-8.

PubMed ID: 30442135

Zhonghua Liu, Fang Liu, Yijian Gao, Weixia Qing, Yongwei Huang, Shengliang Li, and Dongzhu Jin. AIEgen Nanoparticles of Arylamino Fumaronitrile Derivative with High Near-Infrared Emission for Two-Photon Imaging and in Vivo Cell Tracking. ACS Appl. Bio Mater., 2019, 2 (1), pp 430–436. doi: 10.1021/acsabm.8b00643


Huang C, Li C, Muhemaitia P. Impediment of selenite-induced cataract in rats by combinatorial drug laden liposomal preparation. Libyan J Med. 2019 Dec;14(1):1548252. doi: 10.1080/19932820.2018.1548252.

PubMed ID: 30460877

Rizvi I, Nath S, Obaid G, Ruhi MK, Moore K, Bano S, Kessel D, Hasan T. A Combination of Visudyne and a Lipid-anchored Liposomal Formulation of Benzoporphyrin Derivative Enhances Photodynamic Therapy Efficacy in a 3D Model for Ovarian Cancer. Photochem Photobiol. 2019 Jan;95(1):419-429. doi: 10.1111/php.13066. Epub 2019 Jan 7.

PubMed ID: 30499113

Yang F, Zheng Z, Xue X, Zheng L, Qin J, Li H, Zhou Y, Fang G. Targeted eradication of gastric cancer stem cells by CD44 targeting USP22 small interfering RNA-loaded nanoliposomes. Future Oncol. 2019 Jan;15(3):281-295. doi: 10.2217/fon-2018-0295. Epub 2018 Dec 13.

PubMed ID: 30543303

Cardoso BD, Rio ISR, Rodrigues ARO, Fernandes FCT, Almeida BG, Pires A, Pereira AM, Araújo JP, Castanheira EMS, Coutinho PJG. Magnetoliposomes containing magnesium ferrite nanoparticles as nanocarriers for the model drug curcumin. R Soc Open Sci. 2018 Oct 17;5(10):181017. doi: 10.1098/rsos.181017. eCollection 2018 Oct.

PubMed ID: 30473847

Song Y, Li W, Meng S, Zhou W, Su B, Tang L, Zhao Y, Wu X, Yin D, Fan M, Zhou C. Dual integrin αvβ 3 and NRP-1-Targeting Paramagnetic Liposome for Tumor Early Detection in Magnetic Resonance Imaging. Nanoscale Res Lett. 2018 Nov 27;13(1):380. doi: 10.1186/s11671-018-2797-6.

PubMed ID: 30483904

Lin C, Hu Z, Yuan G, Su H, Zeng Y, Guo Z, Zhong F, Jiang K, Songqing H. HIF1α-siRNA and gemcitabine combination-based GE-11 peptide antibody-targeted nanomedicine for enhanced therapeutic efficacy in pancreatic cancers. J Drug Target. 2018 Nov 27:1-30. doi: 10.1080/1061186X.2018.1552276. [Epub ahead of print]

PubMed ID: 30481072

Mahendra A, James HP, Jadhav S. PEG-grafted phospholipids in vesicles: Effect of PEG chain length and concentration on mechanical properties. Chem Phys Lipids. 2019 Jan;218:47-56. doi: 10.1016/j.chemphyslip.2018.12.001. Epub 2018 Dec 3.

PubMed ID: 30521788

Juang EK, De Cock I, Keravnou C, Gallagher MK, Keller SB, Zheng Y, Averkiou M. Engineered 3D microvascular networks for the study of ultrasound-microbubble-mediated drug delivery. Langmuir. 2018 Dec 12. doi: 10.1021/acs.langmuir.8b03288. [Epub ahead of print].

PubMed ID: 30540481

Liu Z, Zhang J, Tian Y, Zhang L, Han X, Wang Q, Cheng W. Targeted delivery of reduced graphene oxide nanosheets using multifunctional ultrasound nanobubbles for visualization and enhanced photothermal therapy. Int J Nanomedicine. 2018 Nov 22;13:7859-7872. doi: 10.2147/IJN.S181268. eCollection 2018.

PubMed ID: 30538464

Olden BR, Perez CR, Wilson AL, Cardle II, Lin YS, Kaehr B, Gustafson JA, Jensen MC, Pun SH. Cell-Templated Silica Microparticles with Supported Lipid Bilayers as Artificial Antigen-Presenting Cells for T Cell Activation. Adv Healthc Mater. 2019 Jan;8(2):e1801188. doi: 10.1002/adhm.201801188. Epub 2018 Dec 13.

PubMed ID: 30549244

Liu X, Jiang J, Chan R, Ji Y, Lu J, Liao YP, Okene M, Lin J, Lin P, Chang CH, Wang X, Tang I, Zheng E, Qiu W, Wainberg ZA, Nel AE, Meng H. Improved Efficacy and Reduced Toxicity Using a Custom-Designed Irinotecan-Delivering Silicasome for Orthotopic Colon Cancer. ACS Nano. 2018 Dec 11. doi: 10.1021/acsnano.8b06164. [Epub ahead of print]

PubMed ID: 30525443

Kulkarni JA, Darjuan MM, Mercer JE, Chen S, van der Meel R, Thewalt JL, Tam YYC, Cullis PR. Formation and Morphology of Lipid Nanoparticles Containing Ionizable Cationic Lipids and siRNA. ACS Nano. 2018 Apr 6. doi: 10.1021/acsnano.8b01516.

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Kakimoto Y, Tachihara Y, Okamoto Y, Miyazawa K, Fukuma T, Tero R. Morphology and Physical Properties of Hydrophilic-Polymer-Modified Lipids in Supported Lipid Bilayers. Langmuir. 2018 Jun 4. doi: 10.1021/acs.langmuir.8b00870. [Epub ahead of print]

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Kakimoto Y, Tachihara Y, Okamoto Y, Miyazawa K, Fukuma T, Tero R. Morphology and Physical Properties of Hydrophilic-Polymer-Modified Lipids in Supported Lipid Bilayers. Langmuir. 2018 May 23. doi: 10.1021/acs.langmuir.8b00870. [Epub ahead of print]

PubMed ID: 29788718

Huiqing Lv , Zhongmin Zhang, Xiaoyu Wu , Yaoxia Wang, Chenglin Li, Weihong Gong, Liang Gui , Xin Wang Preclinical Evaluation of Liposomal C8 Ceramide as a Potent anti-Hepatocellular Carcinoma Agent. Plos One: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0145195

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