870851 | C16 Carnitine

palmitoyl L-carnitine


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C16 Carnitine

C16 Carnitine

palmitoyl L-carnitine

Free fatty acid in the cytosol is attached with a thioester bond to coenzyme A (CoA). This reaction is catalyzed by the enzyme fatty acyl-CoA synthetase and driven to completion by inorganic pyrophosphatase. The acyl group on CoA can now be transferred to carnitine and the resulting acylcarnitine transported into the mitochondrial matrix.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C23H45NO4
Percent Composition
C 69.13%, H 11.35%, N 3.51%, O 16.02%
Purity
<99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
1935-18-8
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
399.608
Exact Mass
399.335

Cheng X, Geng F, Pan M, Wu X, Zhong Y, Wang C, Tian Z, Cheng C, Zhang R, Puduvalli V, Horbinski C, Mo X, Han X, Chakravarti A, Guo D. Targeting DGAT1 Ameliorates Glioblastoma by Increasing Fat Catabolism and Oxidative Stress. Cell Metab. 2020 Jun 9:S1550-4131(20)30303-X. doi: 10.1016/j.cmet.2020.06.002. Epub ahead of print. PMID: 32559414.

PubMed ID: 32559414

Carland JE, Mansfield RE, Ryan RM, Vandenberg RJ. Oleoyl-L-carnitine inhibits glycine transport by GlyT2. Br J Pharmacol. 2013 Feb;168(4):891-902. doi: 10.1111/j.1476-5381.2012.02213.x. PMID: 22978602; PMCID: PMC3631378.

PubMed ID: 22978602