870620 | ACe-1

N-[(E)-4-(4-((4-butylphenyl)diazenyl)phenyl)butanoyl]-D-erythro-sphingosine


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5mg 870620P-5mg 870620P-5mg 1 x 5mg $446.35
25mg 870620P-25mg 870620P-25mg 1 x 25mg $1,689.50
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ACe-1

ACe-1

N-[(E)-4-(4-((4-butylphenyl)diazenyl)phenyl)butanoyl]-D-erythro-sphingosine

Ceramide is a pro-apoptotic sphingolipid. Ceramide's generation can modulate the structure of lipid rafts. ACe-1 is a modified ceramide with an azobenzene moiety to allow for optical control of the N-acyl chain. ACe-1 has been shown to enable the reversible switching of lipid domains in raft-mimicking supported bilayers. Research has shown that in the trans- configuration the ACes are in the liquid-ordered phase and in the cis- configuration the ACes are in the liquid disordered phase in lipid rafts. 

James Allen Frank, Henri G. Franquelim, Petra Schwille, and Dirk Trauner. Journal of the American Chemical Society 2016 138 (39), 12981-12986. DOI: 10.1021/jacs.6b07278

Hygroscopic
No
Light Sensitive
No
Molecular Formula

C38H59N3O3

Percent Composition

C 75.33% H 9.82% N 6.94% O 7.92%

Purity
>99%
Stability
One Year
Storage Temperature
-20°C
CAS Number
2260670-55-9
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
0.000
Exact Mass
605.460