870601 | Azelaoyl-PAF

1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine

Powder

Size SKU Packaging Price
1mg 870601P-1mg 870601P-1mg 1 x 1mg $106.05

Chloroform

Size SKU Packaging Price
1mg 870601C-1mg 870601C-1mg 1 x 1mg 1mg/mL 1mL $106.05
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Azelaoyl-PAF

Azelaoyl-PAF

1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine

Azelaoyl-PAF is an alkyl phosphatidylcholine and is a component of the lipid pool within oxidized low-density lipoprotein (oxLDL) particles. Azelaoyl-PAF is a low molecular weight phospholipid that acts as a high affinity ligand and agonist for PPARγ (peroxisome proliferator-activated receptor-γ).

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C33H66NO9P
Percent Composition
C 60.80%, H 10.21%, N 2.15%, O 22.09%, P 4.75%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
354583-69-0
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
651.852
Exact Mass
651.448
Synonyms
<p>C16-09:0 (COOH) PC</p>
Davies, S.S., Pontsler, A.V., Marathe, G.K., Harrison, K.A., Murphy, R.C., Hinshaw, J.C., Prestwich, G.D., Hilaire, A.S., Prescott, S.M., Zimmerman, G.A., McIntyre, T.M. (2001) Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor-γ ligands and agonists. J. Biol. Chem. 276:16015-16023. [PubMed] Tontonoz, P., Nagy, L., Alvarez, J.G.A., Thomazy, V.A., Evans, R.M. (1998) PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 93:241-252. [PubMed]