870601 | Azelaoyl-PAF

1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine

Powder

Size SKU Packaging Price
1mg 870601P-1mg 870601P-1mg 1 x 1mg $108.70

Chloroform

Size SKU Packaging Price
1mg 870601C-1mg 870601C-1mg 1 x 1mg 1mg/mL 1mL $108.70
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Azelaoyl-PAF

Azelaoyl-PAF

1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine

Azelaoyl-PAF is an alkyl phosphatidylcholine and is a component of the lipid pool within oxidized low-density lipoprotein (oxLDL) particles. Azelaoyl-PAF is a low molecular weight phospholipid that acts as a high affinity ligand and agonist for PPARγ (peroxisome proliferator-activated receptor-γ).

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C33H66NO9P
Percent Composition
C 60.80%, H 10.21%, N 2.15%, O 22.09%, P 4.75%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
354583-69-0
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
651.852
Exact Mass
651.448
Synonyms
<p>C16-09:0 (COOH) PC</p>

Davies SS, Pontsler AV, Marathe GK, Harrison KA, Murphy RC, Hinshaw JC, Prestwich GD, Hilaire AS, Prescott SM, Zimmerman GA, McIntyre TM. Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor gamma ligands and agonists. J Biol Chem. 2001 May 11;276(19):16015-23. doi: 10.1074/jbc.M100878200. Epub 2001 Feb 26. PMID: 11279149.

 PubMed ID: 11279149

Tontonoz P, Nagy L, Alvarez JG, Thomazy VA, Evans RM. PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell. 1998 Apr 17;93(2):241-52. doi: 10.1016/s0092-8674(00)81575-5. PMID: 9568716.

 PubMed ID: 9568716