870320 | N-palmitoyl homocysteine (PHC)

N-palmitoyl homocysteine (ammonium salt)


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N-palmitoyl homocysteine (PHC)

N-palmitoyl homocysteine (PHC)

N-palmitoyl homocysteine (ammonium salt)

When pH-sensitive molecules are incorporated into liposomes, compounds entrapped in the liposome can be specifically released from these vesicles by a change of pH. DOPE liposomes containing PHC deliver their contents at the early endosome.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C20H42N2O3S
Percent Composition
C 61.49%, H 10.84%, N 7.17%, O 12.29%, S 8.21%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
474942-73-9
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
390.624
Exact Mass
390.292
Synonyms
<p>PHCPamHcy</p>
Collins, D., Maxfield, F., Huang, L. (1989) Immunoliposomes with different acid sensitivities as probes for the cellular endocytic pathway. Biochim Biophys Acta. 987:47-55. [PubMed] Connor, J., Huang, L. (1985) Efficient cytoplasmic delivery of a fluorescent dye by pH-sensitive immunoliposomes. J Cell Biol. 101:582-9. [PubMed] Connor, J., Yatvin, M.B., Huang, L. (1984) pH-sensitive liposomes: acid-induced liposome fusion. Proc Natl Acad Sci U S A. 81:1715-8. [PubMed] Yatvin, M.B., Kreutz, W., Horwitz, B.A., Shinitzky, M. (1980) pH-sensitive liposomes: possible clinical implications. Science. 210:1253-5. [PubMed]