870320 | N-palmitoyl homocysteine (PHC)

N-palmitoyl homocysteine (ammonium salt)


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N-palmitoyl homocysteine (PHC)

N-palmitoyl homocysteine (PHC)

N-palmitoyl homocysteine (ammonium salt)

When pH-sensitive molecules are incorporated into liposomes, compounds entrapped in the liposome can be specifically released from these vesicles by a change of pH. DOPE liposomes containing PHC deliver their contents at the early endosome.
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C20H42N2O3S
Percent Composition
C 61.49%, H 10.84%, N 7.17%, O 12.29%, S 8.21%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
474942-73-9
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
390.624
Exact Mass
390.292
Synonyms
PHCPamHcy
Collins, D., Maxfield, F., Huang, L. (1989) Immunoliposomes with different acid sensitivities as probes for the cellular endocytic pathway. Biochim Biophys Acta. 987:47-55. [PubMed] Connor, J., Huang, L. (1985) Efficient cytoplasmic delivery of a fluorescent dye by pH-sensitive immunoliposomes. J Cell Biol. 101:582-9. [PubMed] Connor, J., Yatvin, M.B., Huang, L. (1984) pH-sensitive liposomes: acid-induced liposome fusion. Proc Natl Acad Sci U S A. 81:1715-8. [PubMed] Yatvin, M.B., Kreutz, W., Horwitz, B.A., Shinitzky, M. (1980) pH-sensitive liposomes: possible clinical implications. Science. 210:1253-5. [PubMed]