870320 | N-palmitoyl homocysteine (PHC)

N-palmitoyl homocysteine (ammonium salt)


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N-palmitoyl homocysteine (PHC)

N-palmitoyl homocysteine (PHC)

N-palmitoyl homocysteine (ammonium salt)

When pH-sensitive molecules are incorporated into liposomes, compounds entrapped in the liposome can be specifically released from these vesicles by a change of pH. DOPE liposomes containing PHC deliver their contents at the early endosome.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C20H42N2O3S
Percent Composition
C 61.49%, H 10.84%, N 7.17%, O 12.29%, S 8.21%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
474942-73-9
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
390.624
Exact Mass
390.292
Synonyms
<p>PHCPamHcy</p>

Collins D, Maxfield F, Huang L. Immunoliposomes with different acid sensitivities as probes for the cellular endocytic pathway. Biochim Biophys Acta. 1989 Dec 11;987(1):47-55. doi: 10.1016/0005-2736(89)90453-7. PMID: 2597686.

PubMed ID: 2597686

Connor J, Huang L. Efficient cytoplasmic delivery of a fluorescent dye by pH-sensitive immunoliposomes. J Cell Biol. 1985 Aug;101(2):582-9. doi: 10.1083/jcb.101.2.582. PMID: 4019583; PMCID: PMC2113669.

PubMed ID: 4019583

Connor J, Yatvin MB, Huang L. pH-sensitive liposomes: acid-induced liposome fusion. Proc Natl Acad Sci U S A. 1984 Mar;81(6):1715-8. doi: 10.1073/pnas.81.6.1715. PMID: 6584905; PMCID: PMC344989.

PubMed ID: 6584905

Yatvin MB, Kreutz W, Horwitz BA, Shinitzky M. pH-sensitive liposomes: possible clinical implications. Science. 1980 Dec 12;210(4475):1253-5. doi: 10.1126/science.7434025. PMID: 7434025.

PubMed ID: 7434025