870295 | DSPE-RGD

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-(cysarginylglycylaspartate-maleimidomethyl)cyclohexane-carboxamide] (sodium salt)


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DSPE-RGD

DSPE-RGD

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-(cysarginylglycylaspartate-maleimidomethyl)cyclohexane-carboxamide] (sodium salt)

RGD modified liposomes show potential for cancer research

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C68H120N9Na2O18PS
Percent Composition
C 55.91%, H 8.28%, N 8.63%, Na 3.15%, O 19.72%, P 2.12%, S 2.20%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
2260795-79-5
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
1460.748
Exact Mass
1459.801
Synonyms
sodium (6S,12S,15R)-1-amino-6-ammonio-15-(((1-((4-((2-((((R)-2,3-bis(stearoyloxy)propoxy)oxidophosphoryl)oxy)ethyl)carbamoyl)cyclohexyl)methyl)-2,5-dioxopyrrolidin-3-yl)thio)methyl)-12-(carboxylatomethyl)-1-imino-7,10,13-trioxo-2,8,11,14-tetraazahexadecan-16-oate

Chen CW, Lu DW, Yeh MK, Shiau CY, Chiang CH. Novel RGD-lipid conjugate-modified liposomes for enhancing siRNA delivery in human retinal pigment epithelial cells. Int J Nanomedicine. 2011;6:2567-80. doi: 10.2147/IJN.S24447. Epub 2011 Oct 26. PMID: 22128247; PMCID: PMC3225218.

PubMed ID: 22128247

Cao Y, Zhou Y, Zhuang Q, Cui L, Xu X, Xu R, He X. Anti-tumor effect of RGD modified PTX loaded liposome on prostatic cancer. Int J Clin Exp Med. 2015 Aug 15;8(8):12182-91. PMID: 26550128; PMCID: PMC4612813.

PubMed ID: 26550128