23:2 Diyne PC [DC(8,9)PC] | 870016
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- The UV wavelength for efficient polymerization of diacetylene-containing lipids is 254nm.
- Protect diacetylene phospholipids from light, especially in solution.
- Diacetylene phospholipids will spontaneously polymerize in solution. Store the lipid as a powder for maximum stability.
- Recommend storage at -20° C or less.
- It has been found that the photosensitivity of diacetylenic containing membranes is dependent upon its thermal history. Membranes composed of diacetylenic lipids are light sensitive when prepared below the phase trasition but become insensitive to light after the membranes are heated above the transition temperature (40°C). The membranes remain insensitive to light even after they are cooled to 25°C, and only when they are cooled to near 0°C is light sensitivity regained.
- Photopolymerization of diacetylenic and non-polymerizable lipid (DOPC, DSPC etc.) mixtures depends upon lipid miscibility. High degrees of polymerization cannot be achieved in lipid mixtures where the diacetylenic groups are diluted by other non-polymerizable lipids.
- Molecular Formula
- Percent Composition
- C 70.94%, H 10.14%, N 1.53%, O 14.00%, P 3.39%
- 3 Months
- CAS Number
CAS Registry Number is a Registered Trademark of the American Chemical Society
- Molecular Weight
- Exact Mass
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Yavlovich, A., Singh, A., Blumenthal, R., Puri, A. (2011) A novel class of photo-triggerable liposomes containing DPPC:DC(8,9)PC as vehicles for delivery of doxorubicin to cells. Biochim Biophys Acta. 1808:117-26. [PubMed]
Yavlovich, A., Singh, A., Tarasov, S., Capala, J., Blumenthal, R., Puri, A. (2009) Design of liposomes containing photopolymerizable phospholipids for triggered release of contents. J Therm Anal Calorim. 98:97-104. [PubMed]
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Johnston, D.S., Sanghera, S., Pons, M. Chapman, D. (1980) Phospholipid Polymers-Synthesis and Spectral Characteristics. Biochim Biophys Acta. 602:57-69. [PubMed]