860830 | 18:0(2S-OH) Ceramide

N-(2'-(S)-hydroxystearoyl)-D-erythro-sphingosine


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18:0(2S-OH) Ceramide

18:0(2S-OH) Ceramide

N-(2'-(S)-hydroxystearoyl)-D-erythro-sphingosine

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C36H71NO4
Percent Composition
C 74.30%, H 12.30%, N 2.41%, O 11.00%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
34839-04-8
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
581.953
Exact Mass
581.538
Synonyms
110990
Szulc, Z. M., A. Bai, J. Bielawski, N. Mayroo, D. E. Miller, H. Gracz, Y. A. Hannun, and A. Bielawska. "Synthesis, NMR Characterization and Divergent Biological Actions of 2'-Hydroxy-Ceramide/Dihydroceramide Stereoisomers in MCF7 Cells." Bioorg Med Chem 18, no. 21 (2010): 7565-79. [PubMed] Hama, H. (2010) Fatty acid 2-Hydroxylation in mammalian sphingolipid biology. Biochim Biophys Acta. 1801:405-14. [PubMed] Alderson, N.L., Hama, H. (2009) Fatty acid 2-hydroxylase regulates cAMP-induced cell cycle exit in D6P2T schwannoma cells. J Lipid Res. 50:1203-8. [PubMed] Herrero, A.B., Astudillo, A.M., Balboa, M.A., Cuevas, C., Balsinde, J., Moreno, S. (2008) Levels of SCS7/FA2H-mediated fatty acid 2-hydroxylation determine the sensitivity of cells to antitumor PM02734. Cancer Res. 68:9779-87. [PubMed]