860828 | 18:1(2S-OH) Ceramide

N-(2'-(S)-hydroxyoleoyl)-D-erythro-sphingosine


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18:1(2S-OH) Ceramide

18:1(2S-OH) Ceramide

N-(2'-(S)-hydroxyoleoyl)-D-erythro-sphingosine

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C36H69NO4
Percent Composition
C 74.56%, H 11.99%, N 2.42%, O 11.04%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
1246298-53-2
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
579.937
Exact Mass
579.523
Synonyms
<p>110988</p>

Szulc ZM, Bai A, Bielawski J, Mayroo N, Miller DE, Gracz H, Hannun YA, Bielawska A. Synthesis, NMR characterization and divergent biological actions of 2'-hydroxy-ceramide/dihydroceramide stereoisomers in MCF7 cells. Bioorg Med Chem. 2010 Nov 1;18(21):7565-79. doi: 10.1016/j.bmc.2010.08.050. Epub 2010 Sep 28. PMID: 20851613; PMCID: PMC2956829.

PubMed ID: 20851613

Hama H. Fatty acid 2-Hydroxylation in mammalian sphingolipid biology. Biochim Biophys Acta. 2010 Apr;1801(4):405-14. doi: 10.1016/j.bbalip.2009.12.004. Epub 2009 Dec 21. PMID: 20026285; PMCID: PMC2826524.

PubMed ID: 20026285

Alderson NL, Hama H. Fatty acid 2-hydroxylase regulates cAMP-induced cell cycle exit in D6P2T schwannoma cells. J Lipid Res. 2009 Jun;50(6):1203-8. doi: 10.1194/jlr.M800666-JLR200. Epub 2009 Jan 22. PMID: 19171550; PMCID: PMC2681402.

PubMed ID: 19141550

Herrero AB, Astudillo AM, Balboa MA, Cuevas C, Balsinde J, Moreno S. Levels of SCS7/FA2H-mediated fatty acid 2-hydroxylation determine the sensitivity of cells to antitumor PM02734. Cancer Res. 2008 Dec 1;68(23):9779-87. doi: 10.1158/0008-5472.CAN-08-1981. PMID: 19047157.

PubMed ID: 19047157