860825 | 24:1(2R-OH) Ceramide

N-(2'-(R)-hydroxynervonoyl)-D-erythro-sphingosine


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24:1(2R-OH) Ceramide

24:1(2R-OH) Ceramide

N-(2'-(R)-hydroxynervonoyl)-D-erythro-sphingosine

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C42H81NO4
Percent Composition
C 75.96%, H 12.29%, N 2.11%, O 9.64%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
1246298-50-9
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
664.097
Exact Mass
663.617
Synonyms
110985

Szulc ZM, Bai A, Bielawski J, Mayroo N, Miller DE, Gracz H, Hannun YA, Bielawska A. Synthesis, NMR characterization and divergent biological actions of 2'-hydroxy-ceramide/dihydroceramide stereoisomers in MCF7 cells. Bioorg Med Chem. 2010 Nov 1;18(21):7565-79. doi: 10.1016/j.bmc.2010.08.050. Epub 2010 Sep 28. PMID: 20851613; PMCID: PMC2956829.

PubMed ID: 20851613

Hama H. Fatty acid 2-Hydroxylation in mammalian sphingolipid biology. Biochim Biophys Acta. 2010 Apr;1801(4):405-14. doi: 10.1016/j.bbalip.2009.12.004. Epub 2009 Dec 21. PMID: 20026285; PMCID: PMC2826524.

PubMed ID: 20026285

Alderson NL, Hama H. Fatty acid 2-hydroxylase regulates cAMP-induced cell cycle exit in D6P2T schwannoma cells. J Lipid Res. 2009 Jun;50(6):1203-8. doi: 10.1194/jlr.M800666-JLR200. Epub 2009 Jan 22. PMID: 19171550; PMCID: PMC2681402.

PubMed ID: 19171550

Herrero AB, Astudillo AM, Balboa MA, Cuevas C, Balsinde J, Moreno S. Levels of SCS7/FA2H-mediated fatty acid 2-hydroxylation determine the sensitivity of cells to antitumor PM02734. Cancer Res. 2008 Dec 1;68(23):9779-87. doi: 10.1158/0008-5472.CAN-08-1981. PMID: 19047157.

PubMed ID: 19047157