860824 | 24:0(2S-OH) Ceramide

N-(2'-(S)-hydroxylignoceroyl)-D-erythro-sphingosine


Powder

Size SKU Packaging Price
5mg 860824P-5mg 860824P-5mg 1 x 5mg $236.00
Base Price: ${originalprice|money}
Custom Packaging: (${concentration} @$4.00/ea. + $100) ${custompackagingtotal|money}
Packaging: ${concentration}
Item Total: ${totalprice|money}
Please select an option above.
${sku} - ${concentration}

24:0(2S-OH) Ceramide

24:0(2S-OH) Ceramide

N-(2'-(S)-hydroxylignoceroyl)-D-erythro-sphingosine

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C42H83NO4
Percent Composition
C 75.73%, H 12.56%, N 2.10%, O 9.61%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
112317-53-0
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
666.113
Exact Mass
665.632
Synonyms
<p>110984</p>

Peñalva DA, Oresti GM, Dupuy F, Antollini SS, Maggio B, Aveldaño MI, Fanani ML. Atypical surface behavior of ceramides with nonhydroxy and 2-hydroxy very long-chain (C28-C32) PUFAs. Biochim Biophys Acta. 2014 Mar;1838(3):731-8. doi: 10.1016/j.bbamem.2013.11.018. Epub 2013 Dec 5.

PubMed ID: 24315999

Szulc, Z. M., A. Bai, J. Bielawski, N. Mayroo, D. E. Miller, H. Gracz, Y. A. Hannun, and A. Bielawska. "Synthesis, NMR Characterization and Divergent Biological Actions of 2'-Hydroxy-Ceramide/Dihydroceramide Stereoisomers in MCF7 Cells." Bioorg Med Chem 18, no. 21 (2010): 7565-79.

PubMed ID: 20851613

Hama, H. (2010) Fatty acid 2-Hydroxylation in mammalian sphingolipid biology. Biochim Biophys Acta. 1801:405-14.

PubMed ID: 20026285

Alderson, N.L., Hama, H. (2009) Fatty acid 2-hydroxylase regulates cAMP-induced cell cycle exit in D6P2T schwannoma cells. J Lipid Res. 50:1203-8.

PubMed ID: 19171550

Herrero, A.B., Astudillo, A.M., Balboa, M.A., Cuevas, C., Balsinde, J., Moreno, S. (2008) Levels of SCS7/FA2H-mediated fatty acid 2-hydroxylation determine the sensitivity of cells to antitumor PM02734. Cancer Res. 68:9779-87.

PubMed ID: 19047157