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24:0(2R-OH) Ceramide | 860823

N-(2'-(R)-hydroxylignoceroyl)-D-erythro-sphingosine

860823P

Powder

5 mg
$236.00
10 mg
$420.00
25 mg
$872.00
50 mg
$1407.00

All Prices in US Dollars
This product Is pre-packaged in the unit sizes indicated above.
Quantity discounts are available at the 5 and 10 count level.
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  • Data
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Molecular Formula
C42H83NO4
Percent Composition
C 75.73%, H 12.56%, N 2.10%, O 9.61%
Purity
>99%
Stability
1 Years
Storage
-20°C
CAS Number
64655-47-6
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
666.113
Exact Mass
665.632
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Notes
GIF Graphics File. 
GIF Graphics File. 
MDL Molfile. 
CDX File. 
Szulc, Z. M., A. Bai, J. Bielawski, N. Mayroo, D. E. Miller, H. Gracz, Y. A. Hannun, and A. Bielawska. "Synthesis, NMR Characterization and Divergent Biological Actions of 2'-Hydroxy-Ceramide/Dihydroceramide Stereoisomers in MCF7 Cells." Bioorg Med Chem 18, no. 21 (2010): 7565-79. [PubMed] Hama, H. (2010) Fatty acid 2-Hydroxylation in mammalian sphingolipid biology. Biochim Biophys Acta. 1801:405-14. [PubMed] Alderson, N.L., Hama, H. (2009) Fatty acid 2-hydroxylase regulates cAMP-induced cell cycle exit in D6P2T schwannoma cells. J Lipid Res. 50:1203-8. [PubMed] Herrero, A.B., Astudillo, A.M., Balboa, M.A., Cuevas, C., Balsinde, J., Moreno, S. (2008) Levels of SCS7/FA2H-mediated fatty acid 2-hydroxylation determine the sensitivity of cells to antitumor PM02734. Cancer Res. 68:9779-87. [PubMed] Effects of 6-Hydroxyceramides on the Thermotropic Phase Behavior and Permeability of Model Skin Lipid Membranes Andrej Kováčik†, Michaela Šilarová†, Petra Pullmannová†, Jaroslav Maixner‡, and Kateřina Vávrová*†  Langmuir, Article ASAP [PubMed]