860678 | C24 Ceramide-d7 (d18:1-d7/24:0)

N-lignoceroyl-D-erythro-sphingosine (d7)


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C24 Ceramide-d7 (d18:1-d7/24:0)

C24 Ceramide-d7 (d18:1-d7/24:0)

N-lignoceroyl-D-erythro-sphingosine (d7)

Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios thereof in human plasma empowers the prediction of fatal outcome of coronary artery disease. Avanti has now made available these 4 ceramides in a stable isotope form as a convenience for a newly described validated liquid chromatography-tandem mass spectrometry methodology for their clinical-scaled measurement.
Refer: D. Kauhanen et al. (2016). Development and validation of a high-throughput LC-MS/MS assay for routine measurement of molecular ceramides. Anal Bioanal Chem 408:3475-83
Avanti Numbers 860676, 760677, 860678 and 860679 refer.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C42H76D7NO3
Percent Composition
C 76.76%, H 13.80%, N 2.13%, O 7.30%
Purity
>99%
Stability
1 year
Storage Temperature
-20°C
CAS Number
1840942-15-5
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
657.156
Exact Mass
656.681

Kaya S, Aslan İ, Kıraç E, Karaarslan T, Aslan M. Serum Sphingolipidomic Analysis in Acne Vulgaris Patients. Ann Clin Lab Sci. 2019 Mar;49(2):242-248.

PubMed ID: 31028071

Pullmannova P, Ermakova E, Kovacik A, Opalka L, Maixner J, Zbytovska J, Kucerka N, Vavrova K. Long And Very Long Lamellar Phases In Model Stratum Corneum Lipid Membranes. J Lipid Res. 2019 Mar 18. pii: jlr.M090977. doi: 10.1194/jlr.M090977. [Epub ahead of print]

PubMed ID: 30885924

Kauhanen D, Sysi-Aho M, Koistinen KM, Laaksonen R, Sinisalo J, Ekroos K. Development and validation of a high-throughput LC-MS/MS assay for routine measurement of molecular ceramides. Anal Bioanal Chem. 2016 May;408(13):3475-83. doi: 10.1007/s00216-016-9425-z. Epub 2016 Feb 27.

PubMed ID: 26922344