860662 | Sphingosine-1-Phosphate (d20:1)

D-erythro-sphingosine-1-phosphate (C20 base)


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Sphingosine-1-Phosphate (d20:1)

Sphingosine-1-Phosphate (d20:1)

D-erythro-sphingosine-1-phosphate (C20 base)

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C20H42NO5P
Percent Composition
C 58.94%, H 10.39%, N 3.44%, O 19.63%, P 7.60%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
799812-75-2
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
407.525
Exact Mass
407.280

Vutukuri R, Koch A, Trautmann S, Schreiber Y, Thomas D, Mayser F, Meyer Zu Heringdorf D, Pfeilschifter J, Pfeilschifter W, Brunkhorst R. S1P d20:1, an endogenous modulator of S1P d18:1/S1P2 -dependent signaling. FASEB J. 2020 Jan 15:10.1096/fj.201902391R. doi: 10.1096/fj.201902391R. Epub ahead of print. PMID: 31944406.

PubMed ID: 31944406

Chakraborty P, Vaena SG, Thyagarajan K, Chatterjee S, Al-Khami A, Selvam SP, Nguyen H, Kang I, Wyatt MW, Baliga U, Hedley Z, Ngang RN, Guo B, Beeson GC, Husain S, Paulos CM, Beeson CC, Zilliox MJ, Hill EG, Mehrotra M, Yu XZ, Ogretmen B, Mehrotra S. Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity. Cell Rep. 2019 Aug 13;28(7):1879-1893.e7. doi: 10.1016/j.celrep.2019.07.044.

PubMed ID: 31412253

Xiong Y, Piao W, Brinkman CC, Li L, Kulinski JM, Olivera A, Cartier A, Hla T, Hippen KL, Blazar BR, Schwab SR, Bromberg JS. CD4 T cell sphingosine 1-phosphate receptor (S1PR)1 and S1PR4 and endothelial S1PR2 regulate afferent lymphatic migration. Sci Immunol. 2019 Mar 15;4(33). pii: eaav1263. doi: 10.1126/sciimmunol.aav1263.

PubMed ID: 30877143