860658 | sphinganine-d7

D-erythro-sphinganine-d7


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sphinganine-d7

sphinganine-d7

D-erythro-sphinganine-d7

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C18H32D7NO2
Percent Composition
C 70.07%, H 15.02%, N 4.54%, O 10.37%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
1246304-35-7
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
308.551
Exact Mass
308.342

Debeuf N, Zhakupova A, Steiner R, Van Gassen S, Deswarte K, Fayazpour F, Van Moorleghem J, Vergote K, Pavie B, Lemeire K, Hammad H, Hornemann T, Janssens S, Lambrecht BN. The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice. J Allergy Clin Immunol. 2019 Jul 20. pii: S0091-6749(19)30943-1. doi: 10.1016/j.jaci.2019.06.041. [Epub ahead of print]

PubMed ID: 31330218

Storti F, Klee K, Todorova V, Steiner R, Othman A, van der Velde-Visser S, Samardzija M, Meneau I, Barben M, Karademir D, Pauzuolyte V, Boye SL, Blaser F, Ullmer C, Dunaief JL, Hornemann T, Rohrer L, den Hollander A, von Eckardstein A, Fingerle J, Maugeais C, Grimm C. Impaired ABCA1/ABCG1-mediated lipid efflux in the mouse retinal pigment epithelium (RPE) leads to retinal degeneration. Elife. 2019 Mar 13;8. pii: e45100. doi: 10.7554/eLife.45100.

PubMed ID: 30864945

Triplett J, Nicholson G, Sue C, Hornemann T, Yiannikas C. Hereditary sensory and autonomic neuropathy type IC accompanied by upper motor neuron abnormalities and type II juxtafoveal retinal telangiectasias. J Peripher Nerv Syst. 2019 Mar 13. doi: 10.1111/jns.12315. [Epub ahead of print]

PubMed ID: 30866134

Nejatian N, Trautmann S, Thomas D, Pfeilschifter J, Badenhoop K, Koch A, Penna-Martinez M. Vitamin D effects on sphingosine 1-phosphate signaling and metabolism in monocytes from type 2 diabetes patients and controls. J Steroid Biochem Mol Biol. 2019 Feb;186:130-135. doi: 10.1016/j.jsbmb.2018.10.005. Epub 2018 Oct 15.

PubMed ID: 30336275

Alecu I, Othman A, Penno A, Saied EM, Arenz C, von Eckardstein A, Hornemann T.Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathway. J Lipid Res. 2017 Jan;58(1):60-71. doi: 10.1194/jlr.M072421. Epub 2016 Nov 21.

PubMed ID: 27872144