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860657 | sphingosine-d7

D-erythro-sphingosine-d7

sphingosine-d7

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Size SKU Packaging Price
1mg 860657P-1mg 860657P-1mg 1 x 1mg $273.47
5mg 860657P-5mg 860657P-5mg 1 x 5mg $1,184.10
Info

sphingosine-d7

D-erythro-sphingosine-d7

Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C18H30D7NO2
Percent Composition
C 70.53%, H 14.46%, N 4.57%, O 10.44%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
1246304-34-6
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
306.535
Exact Mass
306.326
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References

Zoicas I, Schumacher F, Kleuser B, Reichel M, Gulbins E, Fejtova A, Kornhuber J, Rhein C. The Forebrain-Specific Overexpression of Acid Sphingomyelinase Induces Depressive-Like Symptoms in Mice. Cells. 2020 May 18;9(5):1244. doi: 10.3390/cells9051244. PMID: 32443534; PMCID: PMC7290754.

 PubMed ID: 32443534

Debeuf N, Zhakupova A, Steiner R, Van Gassen S, Deswarte K, Fayazpour F, Van Moorleghem J, Vergote K, Pavie B, Lemeire K, Hammad H, Hornemann T, Janssens S, Lambrecht BN. The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice. J Allergy Clin Immunol. 2019 Jul 20. pii: S0091-6749(19)30943-1. doi: 10.1016/j.jaci.2019.06.041. [Epub ahead of print]

 PubMed ID: 31330218

Morris MC, Kassam F, Bercz A, Beckmann N, Schumacher F, Gulbins E, Makley AT, Goodman MD. The Role of Chemoprophylactic Agents in Modulating Platelet Aggregability After Traumatic Brain Injury. J Surg Res. 2019 Jul 3;244:1-8. doi: 10.1016/j.jss.2019.06.022. [Epub ahead of print]

 PubMed ID: 31279258

Triplett J, Nicholson G, Sue C, Hornemann T, Yiannikas C. Hereditary sensory and autonomic neuropathy type IC accompanied by upper motor neuron abnormalities and type II juxtafoveal retinal telangiectasias. J Peripher Nerv Syst. 2019 Mar 13. doi: 10.1111/jns.12315. [Epub ahead of print]

 PubMed ID: 30866134

Nejatian N, Trautmann S, Thomas D, Pfeilschifter J, Badenhoop K, Koch A, Penna-Martinez M. Vitamin D effects on sphingosine 1-phosphate signaling and metabolism in monocytes from type 2 diabetes patients and controls. J Steroid Biochem Mol Biol. 2019 Feb;186:130-135. doi: 10.1016/j.jsbmb.2018.10.005. Epub 2018 Oct 15.

 PubMed ID: 30336275

Ohno Y, Nara A, Nakamichi S, Kihara A. Molecular mechanism of the ichthyosis pathology of Chanarin-Dorfman syndrome: Stimulation of PNPLA1-catalyzed ω-O-acylceramide production by ABHD5. J Dermatol Sci. 2018 Dec;92(3):245-253. doi: 10.1016/j.jdermsci.2018.11.005. Epub 2018 Nov 20.

 PubMed ID: 30527376

Gao S, Wan Y, Li W, Huang C. Visualized Networking of Co-Regulated Lipids in Human Blood Based on High-Throughput Screening Data: Implications for Exposure Assessment. Environ Sci Technol. 2019 Feb 21. doi: 10.1021/acs.est.8b06289. [Epub ahead of print

 PubMed ID: 30739451

Alecu I, Othman A, Penno A, Saied EM, Arenz C, von Eckardstein A, Hornemann T.Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathway. J Lipid Res. 2017 Jan;58(1):60-71. doi: 10.1194/jlr.M072421. Epub 2016 Nov 21.

 PubMed ID: 27872144
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