860526 | 1-O-Acyl-Ceramide

1-oleoyl-N-heptadecanoyl-D-erythro-sphingosine


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1-O-Acyl-Ceramide

1-O-Acyl-Ceramide

1-oleoyl-N-heptadecanoyl-D-erythro-sphingosine

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C53H101NO4
Percent Composition
C 77.97%, H 12.47%, N 1.72%, O 7.84%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
1246303-19-4
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
816.373
Exact Mass
815.773
Synonyms
C17:0 d18:1 ceramide-1-O-18:1

Bayerle A, Marsching C, Rabionet M, Dworski S, Kamani MA, Chitraju C, Gluchowski NL, Gabriel KR, Herzer S, Jennemann R, Levade T, Medin JA, Sandhoff R. Endogenous levels of 1-O-acylceramides increase upon acidic ceramidase deficiency and decrease due to loss of Dgat1 in a tissue-dependent manner. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 May 28;1865(9):158741. doi: 10.1016/j.bbalip.2020.158741. Epub ahead of print. PMID: 32474112.

PubMed ID: 32474112

Lin MH, Hsu FF, Crumrine D, Meyer J, Elias PM, Miner JH. Fatty acid transport protein 4 is required for incorporation of saturated ultralong-chain fatty acids into epidermal ceramides and monoacylglycerols. Sci Rep. 2019 Sep 13;9(1):13254. doi: 10.1038/s41598-019-49684-y.

PubMed ID: 31519952

Abe, A., Hiraoka, M., Shayman, J.A. (2007) The acylation of lipophilic alcohols by lysosomal phospholipase A2. J Lipid Res 48:2255-63. [PubMed]

PubMed ID: 17626977