860504 | C4 Ceramide (d18:1/4:0)

N-butyroyl-D-erythro-sphingosine


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C4 Ceramide (d18:1/4:0)

C4 Ceramide (d18:1/4:0)

N-butyroyl-D-erythro-sphingosine

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C22H43NO3
Percent Composition
C 71.50%, H 11.73%, N 3.79%, O 12.99%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
74713-58-9
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
369.582
Exact Mass
369.324
Synonyms
N-(butyroyl)-sphing-4-enine

Caohuy H, Yang Q, Eudy Y, Ha TA, Xu AE, Glover M, Frizzell RA, Jozwik C, Pollard HB. Activation of 3-phosphoinositide-dependent kinase 1 (PDK1) and serum- and glucocorticoid-induced protein kinase 1 (SGK1) by short-chain sphingolipid C4-ceramide rescues the trafficking defect of ΔF508-cystic fibrosis transmembrane conductance regulator (ΔF508-CFTR). J Biol Chem. 2014 Dec 26;289(52):35953-68. doi: 10.1074/jbc.M114.598649. Epub 2014 Nov 10. PMID: 25384981; PMCID: PMC4276863.

PubMed ID: 25384981