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1-deoxysphinganine | 860493

1-deoxysphinganine (m18:0)

860493P

Powder

1 mg
$185.00
5 mg
$520.00
10 mg
$740.00
25 mg
$1340.00
50 mg
$2080.00

All Prices in US Dollars
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  • Data
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Molecular Formula
C18H39NO
Percent Composition
C 75.72%, H 13.77%, N 4.91%, O 5.60
Purity
>99%
Stability
1 Years
Storage
-20°C
CAS Number
196497-48-0
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
285.508
Exact Mass
285.303
Synonyms
Spisulosine
(2S,3R)-2-amino-3-hydroxy-octadecane
ES-285
1-deoxy SA
1-deoxySa
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Notes
GIF Graphics File. 
GIF Graphics File. 
MDL Molfile. 
CDX File. 
Dohrn, M.F., A. Othman, S.K. Hirshman, H. Bode, I. Alecu, E. Fahndrich, W. Karges, J. Weis, J.B. Schulz, T. Hornemann, and K.G. Claeys. (2015). Elevation of plasma 1-deoxy-sphingolipids in type 2 diabetes mellitus: a susceptibility to neuropathy? Eur J Neurol 22:806-14, e55. [PubMed]

Jimenez-Rojo, N., J. Sot, J.V. Busto, W.A. Shaw, J. Duan, A.H. Merrill Jr, A. Alonso, and F.M. Goni. (2014). Biophysical Properties of Novel 1-Deoxy-(Dihydro)ceramides Occurring in Mammalian Cells. Biophys J 107:2850-9. [PubMed]

Penno, A., M.M. Reilly, H. Houlden, M. Laura, K. Rentsch, V. Niederkofler, E.T. Stoeckli, G. Nicholson, F. Eichler, R.H. Brown Jr, A. von Eckardstein, and T. Hornemann. (2010). Hereditary sensory neuropathy type 1 is caused by the accumulation of two neurotoxic sphingolipids. J Biol Chem 285:11178-87. [PubMed]

Pruett, S.T., A. Bushnev, K. Hagedorn, M. Adiga, C.A. Haynes, M.C. Sullards, D.C. Liotta, and A.H. Merrill Jr. (2008). Thematic Review Series: Sphingolipids. Biodiversity of sphingoid bases ("sphingosines") and related amino alcohols. J Lipid Res 49:1621-39. [PubMed]

Zitomer, N.C., T. Mitchell, K.A. Voss, G.S. Bondy, S.T. Pruett, E.C. Garnier-Amblard, L.S. Liebeskind, H. Park, E. Wang, M.C. Sullards, A.H. Merrill Jr, and R.T. Riley. (2009). Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals.[Abstract]