860470 | 1-deoxysphingosine

1-deoxysphingosine (m18:1)

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1-deoxysphingosine

1-deoxysphingosine

1-deoxysphingosine (m18:1)

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C18H37NO
Percent Composition
C 76.26%, H 13.16%, N 4.94%, O 5.64%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
193222-34-3
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
283.492
Exact Mass
283.288
Synonyms
1-deoxy SO1-deoxySo
110888

Mouts A, Vattulainen E, Matsufuji T, Kinoshita M, Matsumori N, Slotte JP. On the importance of the C(1)-OH and C(3)-OH functional groups of the long-chain base of ceramide for interlipid interaction and lateral segregation into ceramide-rich domains. Langmuir. 2018 Dec 3. doi: 10.1021/acs.langmuir.8b03237. [Epub ahead of print].

 PubMed ID: 30507134

Mouts A, Vattulainen E, Matsufuji T, Kinoshita M, Matsumori N, Slotte JP. On the importance of the C(1)-OH and C(3)-OH functional groups of the long-chain base of ceramide for interlipid interaction and lateral segregation into ceramide-rich domains. Langmuir 2018, 34, 51, 15864-15870.

PubMed ID: 30507134

Dohrn, M.F., A. Othman, S.K. Hirshman, H. Bode, I. Alecu, E. Fahndrich, W. Karges, J. Weis, J.B. Schulz, T. Hornemann, and K.G. Claeys. (2015). Elevation of plasma 1-deoxy-sphingolipids in type 2 diabetes mellitus: a susceptibility to neuropathy? Eur J Neurol 22:806-14, e55.

PubMed ID: 25623782

Penno, A., M.M. Reilly, H. Houlden, M. Laura, K. Rentsch, V. Niederkofler, E.T. Stoeckli, G. Nicholson, F. Eichler, R.H. Brown Jr, A. von Eckardstein, and T. Hornemann. (2010). Hereditary sensory neuropathy type 1 is caused by the accumulation of two neurotoxic sphingolipids. J Biol Chem 285:11178-87.

PubMed ID: 20097765

Steiner R, Saied EM, Othman A, Arenz C, Maccarone AT, Poad BL, Blanksby SJ, von Eckardstein A, Hornemann T. Elucidating the chemical structure of native 1-deoxysphingosine. J Lipid Res. 2016 Jul;57(7):1194-203. doi: 10.1194/jlr.M067033. Epub 2016 May 10.

 PubMed ID: 27165858