860464 | N-C24:1-deoxysphinganine

N-nervonoyl-1-deoxysphinganine (m18:0/24:1)


Powder

Size SKU Packaging Price
1mg 860464P-1mg 860464P-1mg 1 x 1mg $247.00
Base Price: ${originalprice|money}
Custom Packaging: (${concentration} @$4.00/ea. + $100) ${custompackagingtotal|money}
Packaging: ${concentration}
Item Total: ${totalprice|money}
Please select an option above.
${sku} - ${concentration}

N-C24:1-deoxysphinganine

N-C24:1-deoxysphinganine

N-nervonoyl-1-deoxysphinganine (m18:0/24:1)

Commonly referred to as 1-deoxydihydroceramide (1-deoxyDHCer), this product is the N-acylated form of 1-deoxysphinganine, a potent inhibitor of sphingolipid metabolism. The biological activity of 1-deoxyDHCer is not clearly understood at this time.
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C42H83NO2
Percent Composition
C 79.55%, H 13.19%, N 2.21%, O 5.05%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
1246298-60-1
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
634.114
Exact Mass
633.642
Synonyms
N-(15Z-tetracosenoyl)-1-deoxysphinganine (m18:0/24:1)N-C24:1-1-deoxyDHCer110998
Jimenez-Rojo, N., J. Sot, J.V. Busto, W.A. Shaw, J. Duan, A.H. Merrill Jr, A. Alonso, and F.M. Goni. (2014). Biophysical Properties of Novel 1-Deoxy-(Dihydro)ceramides Occurring in Mammalian Cells. Biophys J 107:2850-9. [PubMed] Pruett, S.T., A. Bushnev, K. Hagedorn, M. Adiga, C.A. Haynes, M.C. Sullards, D.C. Liotta, and A.H. Merrill Jr. (2008). Thematic Review Series: Sphingolipids. Biodiversity of sphingoid bases ("sphingosines") and related amino alcohols. J Lipid Res 49:1621-39. [PubMed] Zitomer, N.C., T. Mitchell, K.A. Voss, G.S. Bondy, S.T. Pruett, E.C. Garnier-Amblard, L.S. Liebeskind, H. Park, E. Wang, M.C. Sullards, A.H. Merrill Jr, and R.T. Riley. (2009). Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals.[Abstract]