860345 | 14:0 PC-d54

1,2-dimyristoyl-d54-sn-glycero-3-phosphocholine


Chloroform

Size SKU Packaging Price
10mg 860345C-10mg 860345C-10mg 1 x 10mg 10mg/mL 1mL $108.20

Powder

Size SKU Packaging Price
10mg 860345P-10mg 860345P-10mg 1 x 10mg $108.20
25mg 860345P-25mg 860345P-25mg 1 x 25mg $193.25
100mg 860345P-100mg 860345P-100mg 1 x 100mg $519.00
200mg 860345P-200mg 860345P-200mg 1 x 200mg $778.00
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14:0 PC-d54

14:0 PC-d54

1,2-dimyristoyl-d54-sn-glycero-3-phosphocholine

Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C36H18NO8PD54
Percent Composition
C 59.05%, H 2.48%, D 14.85%, N 1.91%, O 17.48%, P 4.23%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
78415-49-3
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
732.265
Exact Mass
731.838
Synonyms
<p>DMPC-D54</p>

Sharma VK, Nagao M, Rai DK, Mamontov E. Membrane softening by nonsteroidal anti-inflammatory drugs investigated by neutron spin echo. Phys Chem Chem Phys. 2019 Sep 18;21(36):20211-20218. doi: 10.1039/c9cp03767e.

PubMed ID: 31486459

Nguyen MHL, DiPasquale M, Rickeard BW, Doktorova M, Heberle FA, Scott HL, Barrera FN, Taylor G, Collier CP, Stanley CB, Katsaras J, Marquardt D. Peptide-Induced Lipid Flip-Flop in Asymmetric Liposomes Measured by Small Angle Neutron Scattering. Langmuir. 2019 Sep 10;35(36):11735-11744. doi: 10.1021/acs.langmuir.9b01625. Epub 2019 Aug 27.

PubMed ID: 31408345

Müller S, Schwieger C, Gruhle K, Garamus VM, Hause G, Meister A, Drescher S. Azide-Modified Membrane Lipids: Miscibility with Saturated Phosphatidylcholines. Langmuir. 2019 Sep 24;35(38):12439-12450. doi: 10.1021/acs.langmuir.9b01842. Epub 2019 Sep 10.

PubMed ID: 31456406

Nicolas I, Bordeau V, Bondon A, Baudy-Floc'h M, Felden B. Novel antibiotics effective against gram-positive and -negative multi-resistant bacteria with limited resistance. PLoS Biol. 2019 Jul 9;17(7):e3000337. doi: 10.1371/journal.pbio.3000337. eCollection 2019 Jul.

PubMed ID: 31287812

Fu Q, Piai A, Chen W, Xia K, Chou JJ. Structure determination protocol for transmembrane domain oligomers. Nat Protoc. 2019 Aug;14(8):2483-2520. doi: 10.1038/s41596-019-0188-9. Epub 2019 Jul 3.

PubMed ID: 31270510

Sergey A. Kotenkov, Oleg I. Gnezdilov, Aliya V. Khaliullina, Oleg N. Antzutkin, Roustam S. Gimatdinov, Andrei V. Filippov. Effect of Cholesterol and Curcumin on Ordering of DMPC Bilayers. Applied Magnetic Resonance. 2018 Nov 23. doi: 10.1007/s00723-018-1102-2


Divakara MB, Martinez D, Ravi A, Bhavana V, Ramana V, Habenstein B, Loquet A, Santosh MS. Molecular mechanisms for the destabilization of model membranes by islet amyloid polypeptide. Biophys Chem. 2019 Feb;245:34-40. doi: 10.1016/j.bpc.2018.12.002. Epub 2018 Dec 14.

PubMed ID: 30576976

Sauvage F, Legrand FX, Roux M, Rajkovic I, Weiss TM, Varga Z, Augis L, Nugue G, Debouzy JC, Vergnaud-Gauduchon J, Barratt G. Interaction of dequalinium chloride with phosphatidylcholine bilayers: A biophysical study with consequences on the development of lipid-based mitochondrial nanomedicines. J Colloid Interface Sci. 2019 Mar 1;537:704-715. doi: 10.1016/j.jcis.2018.11.059. Epub 2018 Nov 15.

PubMed ID: 30497059

Miranda C, Booth VK, Morrow MR. Effects of Amphipathic Polypeptides on Membrane Organization Inferred from Studies Using Bicellar Lipid Mixtures. Langmuir. 2018 Sep 20. doi: 10.1021/acs.langmuir.8b02257. [Epub ahead of print]

PubMed ID: 30196696

Harmouche N, Bechinger B. Lipid-Mediated Interactions between the Antimicrobial Peptides Magainin 2 and PGLa in Bilayers. Biophys J. 2018 Aug 16. pii: S0006-3495(18)30936-6. doi: 10.1016/j.bpj.2018.08.009. [Epub ahead of print]

PubMed ID: 30195937

Yang M, Wang K, Lin J, Wang L, Wei F, Zhu JT, Zheng W, Shen L. Gel Phase Membrane Retards Amyloid β-peptide (1-42) Fibrillation by Restricting Slaved Diffusion of Peptides on Lipid Bilayers. Langmuir. 2018 Jun 20. doi: 10.1021/acs.langmuir.8b01315. [Epub ahead of print

PubMed ID: 29925241

Roux, M., E. Sternin, V. Bonnet, C. Fajolles, and F. Djedaini-Pilard. (2013). Dynamic Lipid Lateral Segregation Driven by Lauryl Cyclodextrin Interactions at the Membrane Surface. Langmuir

PubMed ID: 23409976

Liquid Disordered–Liquid Ordered Phase Coexistence in Lipid/Cholesterol Mixtures: A Deuterium 2D NMR Exchange Study Miranda L. Schmidt and James H. Davis* University of Guelph, Department of Physics, 50 Stone Road East, Guelph, Ontario, Canada, N1G 2W1 Langmuir, Article ASAP DOI: 10.1021/acs.langmuir.6b02834 Publication Date (Web): February 6, 2017 Copyright © 2017 American Chemical Society

PubMed ID: 28165749

The Conformation of the Epidermal Growth Factor Receptor Transmembrane Domain Dimer Dynamically Adapts to the Local Membrane EnvironmentEduard V. Bocharov*† , Pavel E. Bragin†, Konstantin V. Pavlov†, Olga V. Bocharova†, Konstantin S. Mineev†, Anton A. Polyansky†‡ , Pavel E. Volynsky†, Roman G. Efremov†§, and Alexander S. Arseniev† Biochemistry, Article ASAP

PubMed ID: 28291355

Reconciling Differences between Lipid Transfer in Free-Standing and Solid Supported Membranes: A Time-Resolved Small-Angle Neutron Scattering Study Benny Wah†, Jeffrey M. Breidigan†, Joseph Adams†, Piotr Horbal†, Sumit Garg†∥, Lionel Porcar‡§, and Ursula Perez-Salas*†∥ Langmuir, Article ASAP

PubMed ID: 28300412

Ausili A, Torrecillas A, deGodos AM, Corbalan-Garcia S, Gomez-Fernandez JC. The phenolic group of α-tocopherol anchors in the lipid-water interface of fully saturated membranes. Langmuir. 2018 Feb 15. doi: 10.1021/acs.langmuir.7b04142. [Epub ahead of print]

PubMed ID: 29447442