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858143 | 18:1 Lyso PS

1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine (sodium salt)

18:1 Lyso PS

Powder

Size SKU Packaging Price
5mg 858143P-5mg 858143P-5mg 1 x 5mg $157.95
10mg 858143P-10mg 858143P-10mg 1 x 10mg $273.40
25mg 858143P-25mg 858143P-25mg 1 x 25mg $466.75
100mg 858143P-100mg 858143P-100mg 1 x 100mg $1,458.00
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Chloroform

Size SKU Packaging Price
5mg 858143C-5mg 858143C-5mg 1 x 5mg 5mg/mL 1mL $157.95 157.95
10mg 858143C-10mg 858143C-10mg 1 x 10mg 10mg/mL 1mL $273.40 273.4
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Info

18:1 Lyso PS

1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine (sodium salt)

Data
Hygroscopic
Yes
Light Sensitive
No
Molecular Formula
C24H45NO9PNa
Percent Composition
C 52.84%, H 8.31%, N 2.57%, Na 4.21%, O 26.39%, P 5.68%
Purity
>99% LPS; may contain up to 10% of the 2-LPS isomer
Stability
1 Year
Storage Temperature
-20°C
CAS Number
326589-90-6
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
545.579
Exact Mass
545.273
Synonyms
1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt)
PS(18:1(9Z)/0:0)
18:1 LPS
C18:1 LPS
110726
Solubility in Different Solvents
Insoluble in ethanol, soluble in DMSO at 1mg/mL, and soluble in Chloroform:Methanol:Water (65:25:4) at 5mg/mL
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References

Eum JY, Lee JC, Yi SS, Kim IY, Seong JK, Moon MH. Aging-related lipidomic changes in mouse serum, kidney, and heart by nanoflow ultrahigh-performance liquid chromatography-tandem mass spectrometry. J Chromatogr A. 2020 Jan 3:460849. doi: 10.1016/j.chroma.2020.460849. Epub ahead of print. PMID: 31928769.

 PubMed ID: 31928769

Shi Q, Jin S, Xiang X, Tian J, Huang R, Li S, Chen C, Xu H, Song C. The metabolic change in serum lysoglycerophospholipids intervened by triterpenoid saponins from Kuding tea on hyperlipidemic mice. Food Funct. 2019 Dec 11;10(12):7782-7792. doi: 10.1039/c9fo02142f.

 PubMed ID: 31782452

Tsugawa H, Satoh A, Uchino H, Cajka T, Arita M, Arita M. Mass Spectrometry Data Repository Enhances Novel Metabolite Discoveries with Advances in Computational Metabolomics. Metabolites. 2019 Jun 24;9(6). pii: E119. doi: 10.3390/metabo9060119.

 PubMed ID: 31238512

Yan Y, Du Z, Chen C, Li J, Xiong X, Zhang Y, Jiang H. Lysophospholipid profiles of apolipoprotein E-deficient mice reveal potential lipid biomarkers associated with atherosclerosis progression using validated UPLC-QTRAP-MS/MS-based lipidomics approach. J Pharm Biomed Anal. 2019 Jul 15;171:148-157. doi: 10.1016/j.jpba.2019.03.062. Epub 2019 Apr 5.

 PubMed ID: 30999225

D'Ambrosio JM, Albanèse V, Čopič A. Following Anterograde Transport of Phosphatidylserine in Yeast in Real Time. Methods Mol Biol. 2019;1949:35-46. doi: 10.1007/978-1-4939-9136-5_4.

 PubMed ID: 30790247

Feng Y, Chen B, Yu Q, Li L. Identification of Double Bond Position Isomers in Unsaturated Lipids by m-CPBA Epoxidation and Mass Spectrometry Fragmentation. Anal Chem. 2019 Jan 4. doi: 10.1021/acs.analchem.8b04905. [Epub ahead of print]

 PubMed ID: 30608661

Nishikawa, M., M. Kurano, H. Ikeda, J. Aoki, and Y. Yatomi. (2014). Lysophosphatidylserine has Bilateral Effects on Macrophages in the Pathogenesis of Atherosclerosis. J Atheroscler Thromb [PubMed]

 PubMed ID: 25445889
Certificates of Analysis

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