857393 | THI
2-acetyl-5-tetrahydroxybutyl imidazole

THI
2-acetyl-5-tetrahydroxybutyl imidazole
CAS Registry Number is a Registered Trademark of the American Chemical Society
2-ATHBI
- ChemDraw File
- 3D Structure
- Structure
- Safety Data Sheet
- Certificate of Analysis (Lot No. 857393P-1MG-A-010 and 5833PGA010)
- Certificate of Analysis (Lot No. 857393P-1MG-B-010 and 5833PGB010)
Schwab SR, Pereira JP, Matloubian M, Xu Y, Huang Y, Cyster JG. Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients. Science. 2005 Sep 9;309(5741):1735-9. doi: 10.1126/science.1113640. PMID: 16151014.
PubMed ID: 16151014Gugasyan R, Coward A, O'Connor L, Shortman K, Scollay R. Emigration of mature T cells from the thymus is inhibited by the imidazole-based compound 2-acetyl-4-tetrahydroxybutylimidazole. Immunology. 1998 Mar;93(3):398-404. doi: 10.1046/j.1365-2567.1998.00434.x. PMID: 9640251; PMCID: PMC1364089.
PubMed ID: 9640251Bradbury MG, Doherty KV, Parish CR, Lyons AB. The immunosuppressive compound 2-acetyl-4-tetrahydroxybutyl imidazole inhibits the allogeneic mixed lymphocyte reaction by sequestration of a recirculating subpopulation of T cells. Immunology. 1996 Jan;87(1):80-5. PMID: 8666439; PMCID: PMC1383971.
PubMed ID: 8666439Vogel P, Donoviel MS, Read R, Hansen GM, Hazlewood J, Anderson SJ, Sun W, Swaffield J, Oravecz T. Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions. PLoS One. 2009;4(1):e4112. doi: 10.1371/journal.pone.0004112. Epub 2009 Jan 1. PMID: 19119317; PMCID: PMC2606024.
PubMed ID: 19119317