857381 | SLM6031434

(R)-2-(3-(4-(octyloxy)-3-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)pyrrolidine-1-carboximidamide


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25mg 857381P-25mg 857381P-25mg 1 x 25mg $495.00
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SLM6031434

SLM6031434

(R)-2-(3-(4-(octyloxy)-3-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)pyrrolidine-1-carboximidamide

Hygroscopic
No
Light Sensitive
No
Molecular Formula

C22H30F3N5O2

Percent Composition

C 58.27%, H 6.67%, F 12.57%, N 15.44%, O 7.06%

Purity
​>99%
Storage Temperature
-20°C
CAS Number
1897379-33-7
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
453.500
Exact Mass
453.240

Patwardhan NN, Morris EA, Kharel Y, Raje MR, Gao M, Tomsig JL, Lynch KR, Santos WL. Structure-activity relationship studies and in vivo activity of guanidine-based sphingosine kinase inhibitors: discovery of SphK1- and SphK2-selective inhibitors. J Med Chem. 2015 Feb 26;58(4):1879-1899. doi: 10.1021/jm501760d. Epub 2015 Feb 13.

PubMed ID: 25643074

Kharel Y, Morris EA, Congdon MD, Thorpe SB, Tomsig JL, Santos WL, Lynch KR. Sphingosine Kinase 2 Inhibition and Blood Sphingosine 1-Phosphate Levels. J Pharmacol Exp Ther. 2015 Oct;355(1):23-31. doi: 10.1124/jpet.115.225862. Epub 2015 Aug 4.

PubMed ID: 26243740