857350 | VPC 32179 (R)

(R)-phosphoric acid mono-{2-octadec-9-enoylamino-3-[4-(pyridin-2-ylmethoxy)-phenyl]-propyl} ester (ammonium salt)


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VPC 32179 (R)

VPC 32179 (R)

(R)-phosphoric acid mono-{2-octadec-9-enoylamino-3-[4-(pyridin-2-ylmethoxy)-phenyl]-propyl} ester (ammonium salt)

VPC 32179 is devoid of agonist activity at the human LPA2 and LPA3 receptors and behaves as a competitive antagonist at the LPA3 receptor. However, VPC 32179 has been found to have partial agonist activity in a cell migration assay; this is most likely due to activity at the LPA1 receptor.

Hygroscopic
Yes
Light Sensitive
No
Molecular Formula
C33H54N3O6P
Percent Composition
C 63.95%, H 8.78%, N 6.78%, O 15.49%, P 5.00%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
799268-76-1
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
619.772
Exact Mass
619.375

Sriwai W, Zhou H, Murthy KS. G(q)-dependent signalling by the lysophosphatidic acid receptor LPA(3) in gastric smooth muscle: reciprocal regulation of MYPT1 phosphorylation by Rho kinase and cAMP-independent PKA. Biochem J. 2008 May 1;411(3):543-51. doi: 10.1042/bj20071299. PMID: 18237278; PMCID: PMC4872639.

PubMed ID: 18237278