VPC 51299 | 857347
All Prices in US Dollars
Quantity discounts may be available at the 5 and 10 count level.
Contact customer service for a quote.
Add your chosen unit to the shopping cart and adjust the quantity to see the discount.
To purchase larger quantities of this product please contact our Customer Service Department
- VPC51299 is a potent low micromolar inhibitor containing a vinyl phosphonate head group and possessing a half-life of approximately 90 min in rats when dosed intravenously. Previously developed LPA1/LPA3 receptor antagonists contain a labile phosphate head group which impairs evaluation of scaffold LPA receptor antagonists in vivo. VPC51299 has replaced the phosphate with a more stable head group while retaining potency at both LPA1 and LPA3 to facilitate future in vivo studies of the biological functions of these receptors.
Refer: J.E. East, et al. (2011). Development of a phosphatase-resistant, L-tyrosine derived LPA1/LPA3 dual antagonist. Medchemcomm 2:325-330.This product is covered by Patent Number US 8,283,339 B2. Avanti manufactures this under license from University of Virginia.
- Molecular Formula
- C34H50 F3N2O6P
- Percent Composition
- C 60.88%, H 7.51%, F 8.50%, N 4.18%, O 14.31%, P 4.62%
- 1 Years
- Molecular Weight
- Exact Mass