857340 | VPC 32183 (S)

(S)-phosphoric acid mono-{2-octadec-9-enoylamino-3-[4-(pyridin-2-ylmethoxy)-phenyl]-propyl} ester (ammonium salt)


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VPC 32183 (S)

VPC 32183 (S)

(S)-phosphoric acid mono-{2-octadec-9-enoylamino-3-[4-(pyridin-2-ylmethoxy)-phenyl]-propyl} ester (ammonium salt)

VPC 32183(S) is a competitive antagonist at the LPA1 and LPA3 receptors. VPC 32183 is devoid of agonist activity at the human LPA1, LPA2 and LPA3 receptors, and, presumably, at other mammalian LPA receptors.

Hygroscopic
Yes
Light Sensitive
No
Molecular Formula
C33H54N3O6P
Percent Composition
C 63.95%, H 8.78%, N 6.78%, O 15.49%, P 5.00
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
799268-75-0
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
619.772
Exact Mass
619.375

Jia W, Tran SK, Ruddick CA, Murph MM. The Src homology 3 binding domain is required for lysophosphatidic acid 3 receptor-mediated cellular viability in melanoma cells. Cancer Lett. 2015 Jan 28;356(2 Pt B):589-96. doi: 10.1016/j.canlet.2014.10.001. Epub 2014 Oct 7. PMID: 25304369.

PubMed ID: 25304369