Products

(2S)-OMPT | 857235

1-oleoyl-2-methyl-sn-glycero-3-phosphothionate (ammonium salt)

857235P

Powder

500 μg
$89.00
1 mg
$145.00
5 mg
$590.00
10 mg
$1050.00

All Prices in US Dollars
Custom packaging is calculated at $4.00 per aliquot and will be charged at the time of shipping.

Custom Packaging: Before clicking add to cart, from the drop down arrow select custom packaging. Next, edit the quantities (and concentration for solutions) information. Finally, click add to cart.

  • Product
  • Data
  • Downloads
  • Reference
OMPT is a selective agonist of the LPA3 receptor. It exhibits EC50 values of 68 nM and >6.8 µM for calcium mobilization in LPA3 and LPA2-expressing Sf9 cells, respectively.1 The (2S)-OMPT enantiomer is 5- to 20-fold more active than (2R)-OMPT in calcium release assays in both LPA3-transfected Sf9 and rat hepatoma Rh7777 cells.2
 
1. Hasegawa, Y., Erickson, J.R., Goddard, G.J., Yu, S., Liu, S., Cheng, K.W., Eder, A., Bandoh, K., Aoki, J., Jarosz, R., Schrier, A.D., Lynch, K.R., Mills, G.B., Fang, X. (2003) Identification of a phosphothionate analogue of lysophosphatidic acid (LPA) as a selective agonist of the LPA3 receptor. J Biol Chem 278:11962-11969.
 
2. Qian, L., Xu, Y., Hasegawa, Y., Aoki, J., Mills, G.B., Prestwich, G.D. (2003) Enantioselective responses to a phosphorothioate analogue of lysophosphatidic acid with LPA3 receptor-selective agonist activity. J Med Chem 46:5575-5578.
Molecular Formula
C22H46NO6PS
Percent Composition
C 54.63%, H 9.59%, N 2.90%, O 19.85%, P 6.40%, S 6.63%
Purity
>99%
Stability
1 Years
Storage
-20°C
CAS Number
799268-70-5
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
483.643
Exact Mass
483.278
Synonyms
(2S)-1-(9Z-octadecenoyl)-2-O-methyl-glycero-3-phosphothionate (ammonium salt)
Download
Notes
GIF Graphics File. 
GIF Graphics File. 
MDL Molfile. 
CDX File. 
Hasegawa, Y., Erickson, J.R., Goddard, G.J., Yu, S., Liu, S., Cheng, K.W., Eder, A., Bandoh, K., Aoki, J., Jarosz, R., Schrier, A.D., Lynch, K.R., Mills, G.B., Fang, X. (2003)Identification of a phosphothionate analogue of lysophosphatidic acid (LPA) as a selective agonist of the LPA3 receptor. J Biol Chem 278:11962-11969.

Qian, L., Xu, Y., Hasegawa, Y., Aoki, J., Mills, G.B., Prestwich, G.D. (2003)Enantioselective responses to a phosphorothioate analogue of lysophosphatidic acid with LPA3 receptor-selective agonist activity. J Med Chem 46:5575-5578.