857230 | C18:1 LPA

1-(9Z-octadecenyl)-2-hydroxy-sn-glycero-3-phosphate (ammonium salt)


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C18:1 LPA

C18:1 LPA

1-(9Z-octadecenyl)-2-hydroxy-sn-glycero-3-phosphate (ammonium salt)

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C21H46NO6P
Percent Composition
C 57.38%, H 10.55%, N 3.19%, O 21.84%, P 7.05%
Purity
>99% LPA; may contain up to 10% of the 2-LPA isomer
Stability
1 Year
Storage Temperature
-20°C
CAS Number
799279-68-8
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
439.567
Exact Mass
439.306
Synonyms
1-O-9-(Z)-octadecenyl-sn-glycero-3-phosphate (ammonium salt)
PA(18:1(9Z)e/0:0)

Moreno-Fernández RD, Rosell-Valle C, Bacq A, Zanoletti O, Cifuentes M, Pérez-Martín M, Gavito AL, García-Fernández MI, Estivill-Torrús G, Rodríguez de Fonseca F, Santín LJ, Sandi C, Pedraza C. LPA1 receptor and chronic stress: Effects on behaviour and the genes involved in the hippocampal excitatory/inhibitory balance. Neuropharmacology. 2020 Mar 1;164:107896. doi: 10.1016/j.neuropharm.2019.107896. Epub 2019 Dec 4. PMID: 31811875.

PubMed ID: 31811875

Mao G, Smyth SS, Morris AJ. Regulation of PLPP3 gene expression by NF-κB family transcription factors. J Biol Chem. 2019 Sep 20;294(38):14009-14019. doi: 10.1074/jbc.RA119.009002. Epub 2019 Jul 30.

PubMed ID: 31362988

Yuqin Wang, Lin Lyu, Xiaotian Zhang, Junjie Zhang. Autotaxin is a novel target of microRNA‐101‐3p. FEBS Open Bio. 2019 February 16;9(4):707-716. doi: 10.1002/2211-5463.12608


Yuqin Wang, Lin Lyu, Xiaotian Zhang, Junjie Zhang. Autotaxin is a novel target of microRNA‐101‐3p. FEBS Open Bio. 2019 February 16;9-4:707-716. doi: 10.1002/2211-5463.12608


Schmid R, Wolf K, Robering JW, Strauß S, Strissel PL, Strick R, Rübner M, Fasching PA, Horch RE, Kremer AE, Boos AM, Weigand A. ADSCs and adipocytes are the main producers in the autotaxin-lysophosphatidic acid axis of breast cancer and healthy mammary tissue in vitro. BMC Cancer. 2018 Dec 19;18(1):1273. doi: 10.1186/s12885-018-5166-z.

PubMed ID: 30567518

Williams JR1, Khandoga AL, Goyal P, Fells JI, Perygin DH, Siess W, Parrill AL, Tigyi G, Fujiwara Y. Unique ligand selectivity of the GPR92/LPA5 lysophosphatidate receptor indicates role in human platelet activation. J Biol Chem. 2009 Jun 19;284(25):17304-19. doi: 10.1074/jbc.M109.003194. Epub 2009 Apr 14.

PubMed ID: 19366702