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Products

16:0-18:1 PE | 850757

1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine

850757P

Powder

850757P-
25mg
$69.00
850757P-
200mg
$206.00
850757P-
500mg
$370.00
850757P-
1g
$540.00

850757C

Chloroform

850757C-
25mg
$69.00
850757C-
200mg
$206.00
850757C-
500mg
$370.00
850757C-
1g
$540.00

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  • Data
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Molecular Formula
C39H76NO8P
Percent Composition
C 65.24%, H 10.67%, N 1.95%, O 17.83%, P 4.31%
Purity
>99%
Stability
1 Year
Storage
-20°C
CAS Number
26662-94-2
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
717.996
Exact Mass
717.531
Transition Temp
25°C (Tm), 71°C (Th)
Synonyms
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine
POPE
PE(16:0/18:1(9Z))
110637
Prior studies have shown that the biological mixture of the two hydrophobic surfactant proteins, SP-B and SP-C, produces faster adsorption of the surfactant lipids to an air/water interface, and that they induce 1-palmitoyl-2-oleoyl phosphatidylethanolamine (POPE) to form inverse bicontinuous cubic phases. Previous studies have shown that SP-B has a much greater effect than SP-C on adsorption. If the two proteins induce faster adsorption and formation of the bicontinuous structures by similar mechanisms, then they should also have different abilities to form the cubic phases. To test this hypothesis, we measured small-angle X-ray scattering on the individual proteins combined with POPE. SP-B replicated the dose-related ability of the combined proteins to induce the cubic phases at temperatures more than 25 degrees C below the point at which POPE alone forms the curved inverse-hexagonal phase. With SP-C, diffraction from cubic structures was either absent or present at very low intensities only with larger amounts of protein. The correlation between the structural effects of inducing curved structures and the functional effects on the rate of adsorption fits with the model in which SP-B promotes adsorption by facilitating formation of an inversely curved, rate-limiting structure.

Chavarha, M., R.W. Loney, K. Kumar, S.B. Rananavare, and S.B. Hall. (2012). Differential effects of the hydrophobic surfactant proteins on the formation of inverse bicontinuous cubic phases. Langmuir 28:16596-604. [PubMed]

Disordering Effects of Digitonin on Phospholipid Monolayers M. Orczyk, K. Wojciechowski , and G. Brezesinski Langmuir, Article ASAP [PubMed]

Charles G. Cranfield, Sónia Troeira Henriques, Boris Martinac, Paul Duckworth, David J. Craik and Bruce Cornell. Kalata B1 and Kalata B2 Have a Surfactant-Like Activity in Phosphatidylethanolomine-Containing Lipid Membranes. Langmuir, Article ASAP [PubMed]

Jordi H. Borrell and Òscar Domènech. Critical Temperature of 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine Monolayers and Its Possible Biological Relevance. J. Phys. Chem. B, Article ASAP [PubMed]

Saba Ghazvini, Ryan Alonso, Nabil Alhakamy, and Prajnaparamita Dhar. pH induced changes in the surface viscosity of unsaturated phospholipids monitored using active interfacial microrheology. Langmuir, Just Accepted Manuscript [PubMed]