850725 | 18:1 (Δ9-Cis) PE (DOPE)

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine


Powder

Size SKU Packaging Price
25mg 850725P-25mg 850725P-25mg 1 x 25mg $77.50
200mg 850725P-200mg 850725P-200mg 2 x 100mg $226.00
500mg 850725P-500mg 850725P-500mg 5 x 100mg $420.00
1g 850725P-1g 850725P-1g 1 x 1g $620.00

Chloroform

Size SKU Packaging Price
25mg 850725C-25mg 850725C-25mg 1 x 25mg 10mg/mL 2.5mL $77.50
200mg 850725C-200mg 850725C-200mg 2 x 100mg 25mg/mL 4mL $226.00
500mg 850725C-500mg 850725C-500mg 5 x 100mg 25mg/mL 4mL $420.00
1g 850725C-1g 850725C-1g 2 x 500mg 25mg/mL 20mL $620.00
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18:1 (Δ9-Cis) PE (DOPE)

18:1 (Δ9-Cis) PE (DOPE)

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

Hygroscopic
Yes
Light Sensitive
No
Molecular Formula
C41H78NO8P
Percent Composition
C 66.19%, H 10.57%, N 1.88%, O 17.20%, P 4.16%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
4004-05-1
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
744.034
Exact Mass
743.547
Synonyms
<p>1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine</p> <p>DOPE</p> <p>PE(18:1(9Z)/18:1(9Z))</p> <p>&nbsp;110635</p>

Jin W, Purves R, Krol E, Badea I, El-Aneed A. Mass Spectrometric Detection and Characterization of Metabolites of Gemini Surfactants Used as Gene Delivery Vectors. J Am Soc Mass Spectrom. 2020 Feb 5;31(2):366-378. doi: 10.1021/jasms.9b00004. Epub 2020 Jan 10. PMID: 31922726.

PubMed ID: 31922726

Dos Santos Souza É, Fernandes RP, Guedes WN, Dos Santos FN, Eberlin MN, Lopes NP, Padovani VD, da Rosa JA. Rhodnius spp. are differentiated based on the peptide/protein profile by matrix-assisted laser desorption/ionization mass spectrometry and chemometric tools. Anal Bioanal Chem. 2020 Feb;412(6):1431-1439. doi: 10.1007/s00216-019-02376-y. Epub 2020 Jan 8. PMID: 31912183.

PubMed ID: 31912186

Zhen S, Liu Y, Lu J, Tuo X, Yang X, Chen H, Chen W, Li X. Human Papillomavirus Oncogene Manipulation Using Clustered Regularly Interspersed Short Palindromic Repeats/Cas9 Delivered by pH-Sensitive Cationic Liposomes. Hum Gene Ther. 2020 Feb 19:10.1089/hum.2019.312. doi: 10.1089/hum.2019.312. Epub ahead of print. PMID: 31973584.

PubMed ID: 31973584

Runfola M, De Simone A, Vendruscolo M, Dobson CM, Fusco G. The N-terminal Acetylation of α-Synuclein Changes the Affinity for Lipid Membranes but not the Structural Properties of the Bound State. Sci Rep. 2020 Jan 14;10(1):204. doi: 10.1038/s41598-019-57023-4. PMID: 31937832; PMCID: PMC6959233.

PubMed ID: 31937832

Meng J, Tagalakis AD, Hart SL. Silencing E3 Ubiqutin ligase ITCH as a potential therapy to enhance chemotherapy efficacy in p53 mutant neuroblastoma cells. Sci Rep. 2020 Jan 23;10(1):1046. doi: 10.1038/s41598-020-57854-6. PMID: 31974512; PMCID: PMC6978385.

PubMed ID: 31974512

Pinnapireddy SR , Giselbrecht J , Strehlow B , Janich C , Husteden C , Meister A , Loppnow H , Sedding D , Erdmann F , Hause G , Brezesinski G , Groth T , Langner A , Bakowsky U , Wölk C . A triple chain polycationic peptide-mimicking amphiphile - efficient DNA-transfer without co-lipids. Biomater Sci. 2019 Dec 17;8(1):232-249. doi: 10.1039/c9bm01093a. PMID: 31681923.

PubMed ID: 31681923

Das D, Bao H, Courtney KC, Wu L, Chapman ER. Resolving kinetic intermediates during the regulated assembly and disassembly of fusion pores. Nat Commun. 2020 Jan 13;11(1):231. doi: 10.1038/s41467-019-14072-7. PMID: 31932584; PMCID: PMC6957489.

PubMed ID: 31932584

Billingsley MM, Singh N, Ravikumar P, Zhang R, June CH, Mitchell MJ. Ionizable Lipid Nanoparticle-Mediated mRNA Delivery for Human CAR T Cell Engineering. Nano Lett. 2020 Feb 5:10.1021/acs.nanolett.9b04246. doi: 10.1021/acs.nanolett.9b04246. Epub ahead of print. PMID: 31951421.

PubMed ID: 31951421

Hou X, Zhang X, Zhao W, Zeng C, Deng B, McComb DW, Du S, Zhang C, Li W, Dong Y. Vitamin lipid nanoparticles enable adoptive macrophage transfer for the treatment of multidrug-resistant bacterial sepsis. Nat Nanotechnol. 2020 Jan;15(1):41-46. doi: 10.1038/s41565-019-0600-1. Epub 2020 Jan 6. PMID: 31907443.

PubMed ID: 31907443

Wang Y, Jonkute R, Lindmark H, Keighron JD, Cans AS. Molecular Crowding and a Minimal Footprint at a Gold Nanoparticle Support Stabilize Glucose Oxidase and Boost Its Activity. Langmuir. 2020 Jan 14;36(1):37-46. doi: 10.1021/acs.langmuir.9b02863. Epub 2020 Jan 3. PMID: 31865701.

PubMed ID: 31865701

Palchetti S, Digiacomo L, Giulimondi F, Pozzi D, Peruzzi G, Ferri G, Amenitsch H, Cardarelli F, Mahmoudi M, Caracciolo G. A mechanistic explanation of the inhibitory role of the protein corona on liposomal gene expression. Biochim Biophys Acta Biomembr. 2020 Mar 1;1862(3):183159. doi: 10.1016/j.bbamem.2019.183159. Epub 2019 Dec 16. PMID: 31857070.

PubMed ID: 31857070

Samaddar S, Mazur J, Boehm D, Thompson DH. Development And In Vitro Characterization Of Bladder Tumor Cell Targeted Lipid-Coated Polyplex For Dual Delivery Of Plasmids And Small Molecules. Int J Nanomedicine. 2019 Dec 4;14:9547-9561. doi: 10.2147/IJN.S225172. PMID: 31824150; PMCID: PMC6900316.

PubMed ID: 31824150

Martínez-Negro M, Sánchez-Arribas N, Guerrero-Martínez A, Moyá ML, Tros de Ilarduya C, Mendicuti F, Aicart E, Junquera E. A Non-Viral Plasmid DNA Delivery System Consisting on a Lysine-Derived Cationic Lipid Mixed with a Fusogenic Lipid. Pharmaceutics. 2019 Nov 27;11(12):632. doi: 10.3390/pharmaceutics11120632. PMID: 31783620; PMCID: PMC6956073.

PubMed ID: 31783620

Li Y, Zhai Y, Liu W, Zhang K, Liu J, Shi J, Zhang Z. Ultrasmall nanostructured drug based pH-sensitive liposome for effective treatment of drug-resistant tumor. J Nanobiotechnology. 2019 Nov 29;17(1):117. doi: 10.1186/s12951-019-0550-7. PMID: 31783863; PMCID: PMC6884872.

PubMed ID: 31783863

Malekkhaiat Häffner S, Nyström L, Strömstedt AA, Li L, van der Plas MJA, Malmsten M. Nanoclay-induced bacterial flocculation for infection confinement. J Colloid Interface Sci. 2020 Mar 7;562:71-80. doi: 10.1016/j.jcis.2019.11.110. Epub 2019 Dec 5. PMID: 31837621.

PubMed ID: 31837621

Rangl M, Schmandt N, Perozo E, Scheuring S. Real time dynamics of Gating-Related conformational changes in CorA. Elife. 2019 Nov 27;8:e47322. doi: 10.7554/eLife.47322. PMID: 31774394; PMCID: PMC6927688.

PubMed ID: 31774394

Ahmed R, Akcan M, Khondker A, Rheinstädter MC, Bozelli JC Jr, Epand RM, Huynh V, Wylie RG, Boulton S, Huang J, Verschoor CP, Melacini G. Atomic resolution map of the soluble amyloid beta assembly toxic surfaces. Chem Sci. 2019 May 21;10(24):6072-6082. doi: 10.1039/c9sc01331h. PMID: 31360412; PMCID: PMC6585597.

PubMed ID: 31360412

Lee GS, Park JW. Interactions of Cinnamycin-Immobilized Gold Nanorods with Biomimetic Membranes. J Membr Biol. 2020 Feb;253(1):37-42. doi: 10.1007/s00232-019-00103-3. Epub 2019 Nov 22.

PubMed ID: 31720015

Lee GS, Park JW. Interactions of Cinnamycin-Immobilized Gold Nanorods with Biomimetic Membranes. J Membr Biol. 2020 Feb;253(1):37-42. doi: 10.1007/s00232-019-00103-3. Epub 2019 Nov 22.

PubMed ID: 31754751

MacDonald S, Wright A, Beuche F, Downes K, Besser M, Symington E, Kelly A, Thomas W. Characterization of a large cohort of patients with unclassified bleeding disorder; clinical features, management of haemostatic challenges and use of global haemostatic assessment with proposed recommendations for diagnosis and treatment. Int J Lab Hematol. 2019 Nov 20. doi: 10.1111/ijlh.13124. [Epub ahead of print]

PubMed ID: 31747136

Masaracchia C, König A, Valiente-Gabioud AA, Peralta P, Favretto F, Strohäker T, Lázaro DF, Zweckstetter M, Fernandez CO, Outeiro TF. Molecular characterization of an aggregation-prone variant of alpha-synuclein used to model synucleinopathies. Biochim Biophys Acta Proteins Proteom. 2020 Jan;1868(1):140298. doi: 10.1016/j.bbapap.2019.140298. Epub 2019 Oct 30.

PubMed ID: 31676453

Tripodi A, Raffaeli G, Scalambrino E, Padovan L, Clerici M, Chantarangkul V, Cavallaro G, Peyvandi F, Mosca F, Ghirardello S. Procoagulant imbalance in preterm neonates detected by thrombin generation procedures. Thromb Res. 2019 Nov 15;185:96-101. doi: 10.1016/j.thromres.2019.11.013. [Epub ahead of print]

PubMed ID: 31786478

Kreiter J, Rupprecht A, Zimmermann L, Moschinger M, Rokitskaya TI, Antonenko YN, Gille L, Fedorova M, Pohl EE. Molecular Mechanisms Responsible for Pharmacological Effects of Genipin on Mitochondrial Proteins. Biophys J. 2019 Nov 19;117(10):1845-1857. doi: 10.1016/j.bpj.2019.10.021. Epub 2019 Oct 24.

PubMed ID: 31706565

Borro BC, Toussaint MS, Bucciarelli S, Malmsten M. Effects of charge contrast and composition on microgel formation and interactions with bacteria-mimicking liposomes. Biochim Biophys Acta Gen Subj. 2019 Nov 15:129485. doi: 10.1016/j.bbagen.2019.129485. [Epub ahead of print]

PubMed ID: 31734459

Almeida AM Jr, Oliveira ON Jr, Aoki PHB. Role of Toluidine Blue-O Binding Mechanism for Photooxidation in Bioinspired Bacterial Membranes. Langmuir. 2019 Dec 24;35(51):16745-16751. doi: 10.1021/acs.langmuir.9b03045. Epub 2019 Dec 9.

PubMed ID: 31746210

Bellefroid C, Lechanteur A, Evrard B, Mottet D, Debacq-Chainiaux F, Piel G. In vitro skin penetration enhancement techniques: A combined approach of ethosomes and microneedles. Int J Pharm. 2019 Dec 15;572:118793. doi: 10.1016/j.ijpharm.2019.118793. Epub 2019 Nov 9.

PubMed ID: 31715350

Xu J, He M, Hou X, Wang Y, Shou C, Cai X, Yuan Z, Yin Y, Lan M, Lou K, Zhao Y, Yang Y, Chen X, Gao F. Safe and Efficacious Diphtheria Toxin-Based Treatment for Melanoma: Combination of a Light-On Gene-Expression System and Nanotechnology. Mol Pharm. 2020 Jan 6;17(1):301-315. doi: 10.1021/acs.molpharmaceut.9b01038. Epub 2019 Dec 11.

PubMed ID: 31765570

Ramadan S, Tammam SN, Shetab Boushehri MA, Breitinger HG, Breitinger U, Mansour S, Lamprecht A. Liposomal delivery of functional transmembrane ion channels into the cell membranes of target cells; a potential approach for the treatment of channelopathies. Int J Biol Macromol. 2019 Nov 19. pii: S0141-8130(19)37521-X. doi: 10.1016/j.ijbiomac.2019.10.238. [Epub ahead of print]

PubMed ID: 31756462

Antonelli M, Benedetti B, Cavaliere C, Cerrato A, Montone CM, Piovesana S, Lagana A, Capriotti AL. Phospholipidome of extra virgin olive oil: Development of a solid phase extraction protocol followed by liquid chromatography-high resolution mass spectrometry for its software-assisted identification. Food Chem. 2020 Apr 25;310:125860. doi: 10.1016/j.foodchem.2019.125860. Epub 2019 Nov 8.

PubMed ID: 31735462

Kulkarni JA, Witzigmann D, Leung J, Tam YYC, Cullis PR. On the role of helper lipids in lipid nanoparticle formulations of siRNA. Nanoscale. 2019 Nov 21;11(45):21733-21739. doi: 10.1039/c9nr09347h.

PubMed ID: 31713568

Godino E, López JN, Foschepoth D, Cleij C, Doerr A, Castellà CF, Danelon C. De novo synthesized Min proteins drive oscillatory liposome deformation and regulate FtsA-FtsZ cytoskeletal patterns. Nat Commun. 2019 Oct 31;10(1):4969. doi: 10.1038/s41467-019-12932-w.

PubMed ID: 31672986

Muñoz-Úbeda M, Tolosa-Díaz A, Bhattacharya S, Junquera E, Aicart E, Natale P, López-Montero I. Gemini-Based Lipoplexes Complement the Mitochondrial Phenotype in MFN1-Knockout Mouse Embryonic Fibroblasts. Mol Pharm. 2019 Nov 5. doi: 10.1021/acs.molpharmaceut.9b00449. [Epub ahead of print]

PubMed ID: 31609634

André EM, Delcroix GJ, Kandalam S, Sindji L, Montero-Menei CN. A Combinatorial Cell and Drug Delivery Strategy for Huntington's Disease Using Pharmacologically Active Microcarriers and RNAi Neuronally-Committed Mesenchymal Stromal Cells. Pharmaceutics. 2019 Oct 12;11(10). pii: E526. doi: 10.3390/pharmaceutics11100526.

PubMed ID: 31614758

Gaillard B, Seguin C, Remy JS, Pons F, Lebeau L. Erufosine (ErPC3) Cationic Prodrugs as Dual Gene Delivery Reagents for Combined Antitumor Therapy. Chemistry. 2019 Dec 5;25(68):15662-15679. doi: 10.1002/chem.201903976. Epub 2019 Nov 4.

PubMed ID: 31549752

Wiedenhoeft T, Tarantini S, Nyúl-Tóth Á, Yabluchanskiy A, Csipo T, Balasubramanian P, Lipecz A, Kiss T, Csiszar A, Csiszar A, Ungvari Z. Fusogenic liposomes effectively deliver resveratrol to the cerebral microcirculation and improve endothelium-dependent neurovascular coupling responses in aged mice. Geroscience. 2019 Oct 25. doi: 10.1007/s11357-019-00102-1. [Epub ahead of print]

PubMed ID: 31654270

Guimaraes PP, Zhang R, Spektor R, Tan M, Chung A, Billingsley MM, El-Mayta R, Riley RS, Wang L, Wilson JM, Mitchell MJ. Ionizable lipid nanoparticles encapsulating barcoded mRNA for accelerated in vivo delivery screening. J Control Release. 2019 Oct 31. pii: S0168-3659(19)30592-9. doi: 10.1016/j.jconrel.2019.10.028. [Epub ahead of print]

PubMed ID: 31678653

Wang L, Niu X, Song Q, Jia J, Hao Y, Zheng C, Ding K, Xiao H, Liu X, Zhang Z, Zhang Y. A Two-Step Precise Targeting Nanoplatform for Tumor Therapy via the Alkyl Radicals Activated by the Microenvironment of Organelles. J Control Release. 2019 Oct 28. pii: S0168-3659(19)30581-4. doi: 10.1016/j.jconrel.2019.10.017. [Epub ahead of print]

PubMed ID: 31672622

Ahnström J, Gierula M, Temenu J, Laffan MA, Lane DA. Partial rescue of naturally occurring active site factor X variants through decreased inhibition by tissue factor pathway inhibitor and antithrombin. J Thromb Haemost. 2019 Aug 29. doi: 10.1111/jth.14627. [Epub ahead of print]

PubMed ID: 31466141

Ravi V, Madhankumar AB, Abraham T, Slagle-Webb B, Connor JR. Liposomal delivery of ferritin heavy chain 1 (FTH1) siRNA in patient xenograft derived glioblastoma initiating cells suggests different sensitivities to radiation and distinct survival mechanisms. PLoS One. 2019 Sep 6;14(9):e0221952. doi: 10.1371/journal.pone.0221952. eCollection 2019.

PubMed ID: 31491006

Yu Guo, Qing-Ying Yu, Ji Zhang, Hui-Zhen Yang, Zheng Huang and Xiao-Qi Yu. Zn(ii)-cyclen complex-based liposomes for gene delivery: the advantage of Zn coordination. New J. Chem., 2019,43, 16138-16147. doi: 10.1039/C9NJ03242H


Kawamura E, Hibino M, Harashima H, Yamada Y. Targeted mitochondrial delivery of antisense RNA-containing nanoparticles by a MITO-Porter for safe and efficient mitochondrial gene silencing. Mitochondrion. 2019 Aug 28;49:178-188. doi: 10.1016/j.mito.2019.08.004. [Epub ahead of print]

PubMed ID: 31472283

Korkut DN, Alves ID, Vogel A, Chabas S, Sharma CM, Martinez D, Loquet A, Salgado GF, Darfeuille F. Structural insights into the AapA1 toxin of Helicobacter pylori. Biochim Biophys Acta Gen Subj. 2019 Aug 30:129423. doi: 10.1016/j.bbagen.2019.129423. [Epub ahead of print]

PubMed ID: 31476357

Liskayová G, Hubčík L, Búcsi A, Fazekaš T, Martínez JC1, Devínsky F, Pisárčik M, Hanulová M, Ritz S, Uhríková D. pH-Sensitive N,N-Dimethylalkane-1-amine N-Oxides in DNA Delivery: From Structure to Transfection Efficiency. Langmuir. 2019 Oct 15;35(41):13382-13395. doi: 10.1021/acs.langmuir.9b02353. Epub 2019 Oct 3.

PubMed ID: 31537066

Kimura S, Khalil IA, Elewa YHA, Harashima H. Spleen selective enhancement of transfection activities of plasmid DNA driven by octaarginine and an ionizable lipid and its implications for cancer immunization. J Control Release. 2019 Sep 14. pii: S0168-3659(19)30550-4. doi: 10.1016/j.jconrel.2019.09.009. [Epub ahead of print]

PubMed ID: 31526828

Ou W, Jiang L, Gu Y, Soe ZC, Kim BK, Gautam M, Poudel K, Pham LM, Phung CD, Chang JH, Kim JR, Ku SK, Yong CS, Kim JO. Regulatory T Cells Tailored with pH-Responsive Liposomes Shape an Immuno-Antitumor Milieu against Tumors. ACS Appl Mater Interfaces. 2019 Oct 9;11(40):36333-36346. doi: 10.1021/acsami.9b11371. Epub 2019 Sep 27.


PubMed ID: 31535550

Bose D, Chakrabarti A. Chaperone potential of erythroid spectrin: Effects of hemoglobin interaction, macromolecular crowders, phosphorylation and glycation. Biochim Biophys Acta Proteins Proteom. 2019 Nov;1867(11):140267. doi: 10.1016/j.bbapap.2019.140267. Epub 2019 Aug 27.

PubMed ID: 31470132

Saigo N, Izumi K, Kawano R. Electrophysiological Analysis of Antimicrobial Peptides in Diverse Species. ACS Omega. 2019 Aug 6;4(8):13124-13130. doi: 10.1021/acsomega.9b01033. eCollection 2019 Aug 20.

PubMed ID: 31460440

Hamal P, Nguyenhuu H, Subasinghege Don V, Kumal RR, Kumar R, McCarley RL, Haber LH. Molecular Adsorption and Transport at Liposome Surfaces Studied by Molecular Dynamics Simulations and Second Harmonic Generation Spectroscopy. J Phys Chem B. 2019 Sep 12;123(36):7722-7730. doi: 10.1021/acs.jpcb.9b05954. Epub 2019 Aug 29.

PubMed ID: 31407578

Jin W, Al-Dulaymi M, Badea I, Leary SC, Rehman J, El-Aneed A. Cellular Uptake and Distribution of Gemini Surfactant Nanoparticles Used as Gene Delivery Agents. AAPS J. 2019 Aug 6;21(5):98. doi: 10.1208/s12248-019-0367-1.

PubMed ID: 31388860

Larsen EK, Weber DK, Wang S, Gopinath T, Blackwell DJ, Dalton MP, Robia SL, Gao J, Veglia G. Intrinsically disordered HAX-1 regulates Ca2+ cycling by interacting with lipid membranes and the phospholamban cytoplasmic region. Biochim Biophys Acta Biomembr. 2019 Aug 7:183034. doi: 10.1016/j.bbamem.2019.183034. [Epub ahead of print]

PubMed ID: 31400305

Huang Z, Zhang XS, Blaser MJ, London E. Helicobacter pylori lipids can form ordered membrane domains (rafts). Biochim Biophys Acta Biomembr. 2019 Aug 23;1861(11):183050. doi: 10.1016/j.bbamem.2019.183050. [Epub ahead of print]

PubMed ID: 31449801

Ghio S, Camilleri A, Caruana M, Ruf VC, Schmidt F, Leonov A, Ryazanov S, Griesinger C, Cauchi RJ, Kamp F, Giese A, Vassallo N. Cardiolipin Promotes Pore-Forming Activity of Alpha-Synuclein Oligomers in Mitochondrial Membranes. ACS Chem Neurosci. 2019 Aug 21;10(8):3815-3829. doi: 10.1021/acschemneuro.9b00320. Epub 2019 Aug 6.

PubMed ID: 31356747

Fabio Vischio, Elisabetta Fanizza, Vito De Bellis, Teresa Sibillano, Chiara Ingrosso, Cinzia Giannini, Valentino Laquintana, Nunzio Denora, Angela Agostiano, Marinella Striccoli, M. Lucia Curri, and Nicoletta Depalo. Near-Infrared Absorbing Solid Lipid Nanoparticles Encapsulating Plasmonic Copper Sulfide Nanocrystals. J. Phys. Chem. C 2019, 123, 23205−23213


Bruna dos Santos Rodrigues, Sushant Lakkadwala, Takahisa Kanekiyo, Jagdish Singh. Development and screening of brain-targeted lipid-based nanoparticles with enhanced cell penetration and gene delivery properties. International Journal of Nanomedicine; Macclesfield Vol. 14, (2019): 6497-6517. DOI:10.2147/IJN.S215941


Einhäupl P, Krook J, Svensson N, Van Acker K, Van Passel S. Eliciting stakeholder needs - An anticipatory approach assessing enhanced landfill mining. Waste Manag. 2019 Oct;98:113-125. doi: 10.1016/j.wasman.2019.08.009. Epub 2019 Aug 21.

PubMed ID: 31445156

Kanamala M, Palmer BD, Jamieson SM, Wilson WR, Wu Z. Dual pH-sensitive liposomes with low pH-triggered sheddable PEG for enhanced tumor-targeted drug delivery. Nanomedicine (Lond). 2019 Aug;14(15):1971-1989. doi: 10.2217/nnm-2018-0510. Epub 2019 Jul 29.

PubMed ID: 31355712

Zhang R, Qiao C, Jia Q, Wang Y, Huang H, Chang W, Wang H, Zhang H, Wang Z. Highly Stable and Long-Circulating Metal-Organic Frameworks Nanoprobes for Sensitive Tumor Detection In Vivo. Adv Healthc Mater. 2019 Jul 31:e1900761. doi: 10.1002/adhm.201900761. [Epub ahead of print]

PubMed ID: 31368240

Zhang R, Qiao C, Jia Q, Wang Y, Huang H, Chang W, Wang H, Zhang H, Wang Z. Highly Stable and Long-Circulating Metal-Organic Frameworks Nanoprobes for Sensitive Tumor Detection In Vivo. Adv Healthc Mater. 2019 Jul 31:e1900761. doi: 10.1002/adhm.201900761. [Epub ahead of print]

PubMed ID: 31368240

Tateshita N, Miura N, Tanaka H, Masuda T, Ohtsuki S, Tange K, Nakai Y, Yoshioka H, Akita H. Development of a lipoplex-type mRNA carrier composed of an ionizable lipid with a vitamin E scaffold and the KALA peptide for use as an ex vivo dendritic cell-based cancer vaccine. J Control Release. 2019 Sep 28;310:36-46. doi: 10.1016/j.jconrel.2019.08.002. Epub 2019 Aug 3.

PubMed ID: 31386869

Park SY, Yang JS, Li Z, Deng P, Zhu X, Young D, Ericsson M, Andringa RLH, Minnaard AJ, Zhu C, Sun F, Moody DB, Morris AJ, Fan J, Hsu VW. The late stage of COPI vesicle fission requires shorter forms of phosphatidic acid and diacylglycerol. Nat Commun. 2019 Jul 30;10(1):3409. doi: 10.1038/s41467-019-11324-4.

PubMed ID: 31363100

Dai A, Yu L, Wang HW. WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes. Nat Commun. 2019 Aug 16;10(1):3699. doi: 10.1038/s41467-019-11694-9.

PubMed ID: 31420534

Ibaraki H, Kanazawa T, Kurano T, Oogi C, Takashima Y, Seta Y. Anti-RelA siRNA-Encapsulated Flexible Liposome with Tight Junction-Opening Peptide as a Non-invasive Topical Therapeutic for Atopic Dermatitis. Biol Pharm Bull. 2019;42(7):1216-1225. doi: 10.1248/bpb.b19-00259.

PubMed ID: 31257297

Dos Santos Souza É, Fernandes RP, Galvão C, de Paiva VF, da Rosa JA. Distinguishing two species of Cavernicola (Hemiptera, Reduviidae, Triatominae) with matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Acta Trop. 2019 Jul 16;198:105071. doi: 10.1016/j.actatropica.2019.105071. [Epub ahead of print]

PubMed ID: 31323194

Mayer SF, Ducrey J, Dupasquier J, Haeni L, Rothen-Rutishauser B, Yang J, Fennouri A, Mayer M. Targeting specific membranes with an azide derivative of the pore-forming peptide ceratotoxin A. Biochim Biophys Acta Biomembr. 2019 Oct 1;1861(10):183023. doi: 10.1016/j.bbamem.2019.07.011. Epub 2019 Jul 17.

PubMed ID: 31325418

Alhareth K, Valero L, Mohamed KE, Fliedel L, Roques C, Gil S, Mignet N, Fournier T, Andrieux K. Qualitative and quantitative analysis of the uptake of lipoplexes by villous placenta explants. Int J Pharm. 2019 Aug 15;567:118479. doi: 10.1016/j.ijpharm.2019.118479. Epub 2019 Jun 27.

PubMed ID: 31255777

Kessenich BL, Pokhrel N, Nakouzi E, Newcomb CJ, Flury M, Maibaum L, De Yoreo JJ. Connecting wettability, topography, and chemistry in a simple lipid-montmorillonite system. J Colloid Interface Sci. 2019 Jul 26;555:498-508. doi: 10.1016/j.jcis.2019.07.075. [Epub ahead of print]

PubMed ID: 31401482

Nordström R, Andrén OCJ, Singh S, Malkoch M, Davoudi M, Schmidtchen A, Malmsten M. Degradable dendritic nanogels as carriers for antimicrobial peptides. J Colloid Interface Sci. 2019 Oct 15;554:592-602. doi: 10.1016/j.jcis.2019.07.028. Epub 2019 Jul 13.

PubMed ID: 31330426

Bruun K, Hille C. Study on intracellular delivery of liposome encapsulated quantum dots using advanced fluorescence microscopy. Sci Rep. 2019 Jul 19;9(1):10504. doi: 10.1038/s41598-019-46732-5.

PubMed ID: 31324829

Izri Z, Garenne D, Noireaux V, Maeda YT. Gene Expression in on-Chip Membrane-Bound Artificial Cells. ACS Synth Biol. 2019 Aug 16;8(8):1705-1712. doi: 10.1021/acssynbio.9b00247. Epub 2019 Jul 11.

PubMed ID: 31268305

Han JH, Park J, Myung SH, Lee SH, Kim HY, Kim KS, Seo YW, Kim TH. Noxa mitochondrial targeting domain induces necrosis via VDAC2 and mitochondrial catastrophe. Cell Death Dis. 2019 Jul 8;10(7):519. doi: 10.1038/s41419-019-1753-4.

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Grunwitz C, Salomon N, Vascotto F, Selmi A, Bukur T, Diken M, Kreiter S, Türeci Ö, Sahin U. HPV16 RNA-LPX vaccine mediates complete regression of aggressively growing HPV-positive mouse tumors and establishes protective T cell memory. Oncoimmunology. 2019 Jul 11;8(9):e1629259. doi: 10.1080/2162402X.2019.1629259. eCollection 2019.

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Goshi M, Pytel N, Elbayoumi T. Partially Polymerized Phospholipid Vesicles for Efficient Delivery of Macromolecules. Methods Mol Biol. 2019;2000:267-277. doi: 10.1007/978-1-4939-9516-5_18.

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Tunsirikongkon A, Pyo YC, Kim DH, Lee SE, Park JS. Optimization of Polyarginine-Conjugated PEG Lipid Grafted Proliposome Formulation for Enhanced Cellular Association of a Protein Drug. Pharmaceutics. 2019 Jun 11;11(6). pii: E272. doi: 10.3390/pharmaceutics11060272.

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Xu N, Shanbhag AG, Li B, Angkuratipakorn T, Decker EA. Impact of Phospholipid-Tocopherol Combinations and Enzyme-Modified Lecithin on the Oxidative Stability of Bulk Oil. J Agric Food Chem. 2019 Jul 17;67(28):7954-7960. doi: 10.1021/acs.jafc.9b02520. Epub 2019 Jul 1.

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Riccardo Di Santo, Erica Quagliarini, Sara Palchetti, Daniela Pozzi, Valentina Palmieri, Giordano Perini, Massimiliano Papi, Anna Laura Capriotti, Aldo Laganà, and Giulio Caracciolo. Microfluidic-generated lipid-graphene oxide nanoparticles for gene delivery. Appl. Phys. Lett. 114, 233701 (2019). doi: 10.1063/1.5100932


Dos Santos Rodrigues B, Banerjee A, Kanekiyo T, Singh J. Functionalized liposomal nanoparticles for efficient gene delivery system to neuronal cell transfection. Int J Pharm. 2019 Jul 20;566:717-730. doi: 10.1016/j.ijpharm.2019.06.026. Epub 2019 Jun 13.

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Rodrigues L, Schneider F, Zhang X, Larsson E, Moodie LWK, Dietz H, Papadakis CM, Winter G, Lundmark R, Hubert M. Cellular uptake of self-assembled phytantriol-based hexosomes is independent of major endocytic machineries. J Colloid Interface Sci. 2019 Jun 19;553:820-833. doi: 10.1016/j.jcis.2019.06.045. [Epub ahead of print]

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Lakkadwala S, Dos Santos Rodrigues B, Sun C, Singh J. Dual functionalized liposomes for efficient co-delivery of anti-cancer chemotherapeutics for the treatment of glioblastoma. J Control Release. 2019 Jun 26;307:247-260. doi: 10.1016/j.jconrel.2019.06.033. [Epub ahead of print]

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Bhaskara RM, Grumati P, Garcia-Pardo J, Kalayil S, Covarrubias-Pinto A, Chen W, Kudryashev M, Dikic I, Hummer G. Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy. Nat Commun. 2019 May 30;10(1):2370. doi: 10.1038/s41467-019-10345-3.

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Chiang CL, Goswami S, Frissora FW, Xie Z, Yan PS, Bundschuh R, Walker LA, Huang X, Mani R, Mo XM, Baskar S, Rader C, Phelps MA, Marcucci G, Byrd JC, Lee LJ, Muthusamy N. ROR1-targeted delivery of miR-29b induces cell cycle arrest and therapeutic benefit in vivo in CLL mouse model. Blood. 2019 May 31. pii: blood.2018882290. doi: 10.1182/blood.2018882290. [Epub ahead of print]

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Hibino M, Yamada Y, Fujishita N, Sato Y, Maeki M, Tokeshi M, Harashima H. The Use of a Microfluidic Device to Encapsulate a Poorly Water-Soluble Drug CoQ10 in Lipid Nanoparticles and an Attempt to Regulate Intracellular Trafficking to Reach Mitochondria. J Pharm Sci. 2019 Apr 5. pii: S0022-3549(19)30214-X. doi: 10.1016/j.xphs.2019.04.001. [Epub ahead of print]

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Velasco-Olmo A, Ormaetxea Gisasola J, Martinez Galvez JM, Vera Lillo J, Shnyrova AV. Combining patch-clamping and fluorescence microscopy for quantitative reconstitution of cellular membrane processes with Giant Suspended Bilayers. Sci Rep. 2019 May 10;9(1):7255. doi: 10.1038/s41598-019-43561-4.

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Wagle S, Georgiev VN, Robinson T, Dimova R, Lipowsky R, Grafmüller A. Interaction of SNARE Mimetic Peptides with Lipid bilayers: Effects of Secondary Structure, Bilayer Composition and Lipid Anchoring. Sci Rep. 2019 May 22;9(1):7708. doi: 10.1038/s41598-019-43418-w.

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Lopes-de-Campos D, Pinto RM, Lima SAC, Santos T, Sarmento B, Nunes C, Reis S. Delivering amoxicillin at the infection site - a rational design through lipid nanoparticles. Int J Nanomedicine. 2019 Apr 23;14:2781-2795. doi: 10.2147/IJN.S193992. eCollection 2019.

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Li H, Liu Q, Crielaard BJ, de Vries JW, Loznik M, Meng Z, Yang X, Göstl R, Herrmann A. Fast, Efficient, and Targeted Liposome Delivery Mediated by DNA Hybridization. Adv Healthc Mater. 2019 May 13:e1900389. doi: 10.1002/adhm.201900389. [Epub ahead of print]

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Liu Z, Wang C, Yang J, Zhou B, Yang R, Ramachandran R, Abbott DW, Xiao TS. Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization. Immunity. 2019 May 8. pii: S1074-7613(19)30197-9. doi: 10.1016/j.immuni.2019.04.017. [Epub ahead of print]

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Silvestre-Roig C, Braster Q, Wichapong K, Lee EY, Teulon JM, Berrebeh N, Winter J, Adrover JM, Santos GS, Froese A, Lemnitzer P, Ortega-Gómez A, Chevre R, Marschner J, Schumski A, Winter C, Perez-Olivares L, Pan C, Paulin N, Schoufour T, Hartwig H, González-Ramos S, Kamp F, Megens RTA, Mowen KA, Gunzer M, Maegdefessel L, Hackeng T, Lutgens E, Daemen M, von Blume J, Anders HJ, Nikolaev VO, Pellequer JL, Weber C, Hidalgo A, Nicolaes GAF, Wong GCL, Soehnlein O. Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death. Nature. 2019 May;569(7755):236-240. doi: 10.1038/s41586-019-1167-6. Epub 2019 May 1.

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Mozaffari S, Bousoik E, Amirrad F, Lamboy R, Coyle M, Hall R, Alasmari A, Mahdipoor P, Parang K, Montazeri Aliabadi H. Amphiphilic Peptides for Efficient siRNA Delivery. Polymers (Basel). 2019 Apr 17;11(4). pii: E703. doi: 10.3390/polym11040703.

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Yao Y, Wang T, Liu Y, Zhang N. Co-delivery of sorafenib and VEGF-siRNA via pH-sensitive liposomes for the synergistic treatment of hepatocellular carcinoma. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):1374-1383. doi: 10.1080/21691401.2019.1596943.

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Izzo L, Matrella S, Mella M, Benvenuto G, Vigliotta G. Escherichia coli as a Model for the Description of the Antimicrobial Mechanism of a Cationic Polymer Surface: Cellular Target and Bacterial Contrast Response. ACS Appl Mater Interfaces. 2019 May 1;11(17):15332-15343. doi: 10.1021/acsami.9b02903. Epub 2019 Apr 19.

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Malekkhaiat Häffner S, Nyström L, Browning KL, Mörck Nielsen H, Strömstedt AA, van der Plas MJA, Schmidtchen A, Malmsten M. Interaction of Laponite with Membrane Components-Consequences for Bacterial Aggregation and Infection Confinement. ACS Appl Mater Interfaces. 2019 May 1;11(17):15389-15400. doi: 10.1021/acsami.9b03527. Epub 2019 Apr 17.

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Zamani P, Navashenaq JG, Nikpoor AR, Hatamipour M, Oskuee RK, Badiee A, Jaafari MR. MPL nano-liposomal vaccine containing P5 HER2/neu-derived peptide pulsed PADRE as an effective vaccine in a mice TUBO model of breast cancer. J Control Release. 2019 Apr 15;303:223-236. doi: 10.1016/j.jconrel.2019.04.019. [Epub ahead of print]

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Lakomek NA, Yavuz H, Jahn R, Pérez-Lara Á. Structural dynamics and transient lipid binding of synaptobrevin-2 tune SNARE assembly and membrane fusion. Proc Natl Acad Sci U S A. 2019 Apr 30;116(18):8699-8708. doi: 10.1073/pnas.1813194116. Epub 2019 Apr 11.

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Blakney AK, McKay PF, Ibarzo Yus B, Hunter JE, Dex EA, Shattock RJ. The Skin You're In: Design of Experiments Optimization of Lipid Nanoparticle Self-Amplifying RNA Formulations in Human Skin Explants. ACS Nano. 2019 May 2. doi: 10.1021/acsnano.9b01774. [Epub ahead of print]

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Bessodes M, Dhotel H, Mignet N. Lipids for Nucleic Acid Delivery: Cationic or Neutral Lipoplexes, Synthesis, and Particle Formation. Methods Mol Biol. 2019;1943:123-139. doi: 10.1007/978-1-4939-9092-4_8.

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Dewitte H, Roovers S, De Smedt SC, Lentacker I. Enhancing Nucleic Acid Delivery with Ultrasound and Microbubbles. Methods Mol Biol. 2019;1943:241-251. doi: 10.1007/978-1-4939-9092-4_16.

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Rhys NH, Duffy IB, Sowden CL, Lorenz CD, McLain SE. On the hydration of DOPE in solution. J Chem Phys. 2019 Mar 21;150(11):115104. doi: 10.1063/1.5085736.

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Maqbool F, Moyle PM, Thurecht KJ, Falconer JR. Dispersibility of phospholipids and their optimization for the efficient production of liposomes using supercritical fluid technology. Int J Pharm. 2019 Mar 30;563:174-183. doi: 10.1016/j.ijpharm.2019.03.053. [Epub ahead of print]

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Möuts A, Yamamoto T, Nyholm TKM, Murata M, Slotte JP. Nonlamellar-Phase-Promoting Colipids Enhance Segregation of Palmitoyl Ceramide in Fluid Bilayers. Biophys J. 2019 Mar 19. pii: S0006-3495(19)30190-0. doi: 10.1016/j.bpj.2019.03.004. [Epub ahead of print]

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Tassler S, Dobner B, Lampp L, Ziółkowski R, Malinowska E, Wölk C, Brezesinski G. DNA Delivery Systems Based on Peptide-Mimicking Cationic Lipids-The Effect of the Co-Lipid on the Structure and DNA Binding Capacity. Langmuir. 2019 Apr 2;35(13):4613-4625. doi: 10.1021/acs.langmuir.8b04139. Epub 2019 Mar 19.

PubMed ID: 30840475